Effects of somatostatin, glucagon and insulin on glycogen synthesis in isolated rat hepatocytes

A. J. Bone; S. I.M. Younan; J. M. Conlon

doi:10.1055/s-2007-1014837

Effects of somatostatin, glucagon and insulin on glycogen synthesis in isolated rat hepatocytes

A. J. Bone, S. I.M. Younan, J. M. Conlon

School of Biomedical Sciences

Newcastle University

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

The effects of somatostatin on basal and hormone-mediated rates of glycogenesis were studied in isolated rat hepatocytes. Somatostatin (1.5 x 10^-11 - 1.5 x 10^-8 M) had no effect on glycogen synthesis in the presence of 30 mM glucose and did not overcome a glucagon (1.5 x 10^-10 M)-induced inhibition of glycogenesis.

Original language	English
Pages (from-to)	513-515
Number of pages	3
Journal	HORMONE AND METABOLIC RESEARCH
Volume	16
Issue number	10
DOIs	https://doi.org/10.1055/s-2007-1014837
Publication status	Published (in print/issue) - 1984

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title = "Effects of somatostatin, glucagon and insulin on glycogen synthesis in isolated rat hepatocytes",

abstract = "The effects of somatostatin on basal and hormone-mediated rates of glycogenesis were studied in isolated rat hepatocytes. Somatostatin (1.5 x 10-11 - 1.5 x 10-8 M) had no effect on glycogen synthesis in the presence of 30 mM glucose and did not overcome a glucagon (1.5 x 10-10 M)-induced inhibition of glycogenesis.",

author = "Bone, \{A. J.\} and Younan, \{S. I.M.\} and Conlon, \{J. M.\}",

year = "1984",

doi = "10.1055/s-2007-1014837",

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T1 - Effects of somatostatin, glucagon and insulin on glycogen synthesis in isolated rat hepatocytes

AU - Bone, A. J.

AU - Younan, S. I.M.

AU - Conlon, J. M.

PY - 1984

Y1 - 1984

N2 - The effects of somatostatin on basal and hormone-mediated rates of glycogenesis were studied in isolated rat hepatocytes. Somatostatin (1.5 x 10-11 - 1.5 x 10-8 M) had no effect on glycogen synthesis in the presence of 30 mM glucose and did not overcome a glucagon (1.5 x 10-10 M)-induced inhibition of glycogenesis.

AB - The effects of somatostatin on basal and hormone-mediated rates of glycogenesis were studied in isolated rat hepatocytes. Somatostatin (1.5 x 10-11 - 1.5 x 10-8 M) had no effect on glycogen synthesis in the presence of 30 mM glucose and did not overcome a glucagon (1.5 x 10-10 M)-induced inhibition of glycogenesis.

UR - https://www.scopus.com/pages/publications/0021718127

U2 - 10.1055/s-2007-1014837

DO - 10.1055/s-2007-1014837

M3 - Article

C2 - 6149990

AN - SCOPUS:0021718127

SN - 0018-5043

VL - 16

SP - 513

EP - 515

JO - HORMONE AND METABOLIC RESEARCH

JF - HORMONE AND METABOLIC RESEARCH

IS - 10

ER -

Effects of somatostatin, glucagon and insulin on glycogen synthesis in isolated rat hepatocytes

Abstract

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