Effects of somatostatin, glucagon and insulin on glycogen synthesis in isolated rat hepatocytes

A. J. Bone; S. I.M. Younan; J. M. Conlon

doi:10.1055/s-2007-1014837

Effects of somatostatin, glucagon and insulin on glycogen synthesis in isolated rat hepatocytes

A. J. Bone, S. I.M. Younan, J. M. Conlon

School of Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

The effects of somatostatin on basal and hormone-mediated rates of glycogenesis were studied in isolated rat hepatocytes. Somatostatin (1.5 x 10^-11 - 1.5 x 10^-8 M) had no effect on glycogen synthesis in the presence of 30 mM glucose and did not overcome a glucagon (1.5 x 10^-10 M)-induced inhibition of glycogenesis.

Original language	English
Pages (from-to)	513-515
Number of pages	3
Journal	HORMONE AND METABOLIC RESEARCH
Volume	16
Issue number	10
DOIs	https://doi.org/10.1055/s-2007-1014837
Publication status	Published (in print/issue) - 1984

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title = "Effects of somatostatin, glucagon and insulin on glycogen synthesis in isolated rat hepatocytes",

abstract = "The effects of somatostatin on basal and hormone-mediated rates of glycogenesis were studied in isolated rat hepatocytes. Somatostatin (1.5 x 10-11 - 1.5 x 10-8 M) had no effect on glycogen synthesis in the presence of 30 mM glucose and did not overcome a glucagon (1.5 x 10-10 M)-induced inhibition of glycogenesis.",

author = "Bone, {A. J.} and Younan, {S. I.M.} and Conlon, {J. M.}",

year = "1984",

doi = "10.1055/s-2007-1014837",

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T1 - Effects of somatostatin, glucagon and insulin on glycogen synthesis in isolated rat hepatocytes

AU - Bone, A. J.

AU - Younan, S. I.M.

AU - Conlon, J. M.

PY - 1984

Y1 - 1984

N2 - The effects of somatostatin on basal and hormone-mediated rates of glycogenesis were studied in isolated rat hepatocytes. Somatostatin (1.5 x 10-11 - 1.5 x 10-8 M) had no effect on glycogen synthesis in the presence of 30 mM glucose and did not overcome a glucagon (1.5 x 10-10 M)-induced inhibition of glycogenesis.

AB - The effects of somatostatin on basal and hormone-mediated rates of glycogenesis were studied in isolated rat hepatocytes. Somatostatin (1.5 x 10-11 - 1.5 x 10-8 M) had no effect on glycogen synthesis in the presence of 30 mM glucose and did not overcome a glucagon (1.5 x 10-10 M)-induced inhibition of glycogenesis.

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U2 - 10.1055/s-2007-1014837

DO - 10.1055/s-2007-1014837

M3 - Article

C2 - 6149990

AN - SCOPUS:0021718127

SN - 0018-5043

VL - 16

SP - 513

EP - 515

JO - HORMONE AND METABOLIC RESEARCH

JF - HORMONE AND METABOLIC RESEARCH

IS - 10

ER -

Effects of somatostatin, glucagon and insulin on glycogen synthesis in isolated rat hepatocytes

Abstract

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