Effects of hypertonic saline and/or carbocisteine on sputum rheology in bronchiectasis (CLEAR-EME)

Michael C. McKelvey; Gisli G. Einarsson; Jack Carson; Aram Kadoom; Ryan R. Brown; Christina Campbell; Andrew Jackson; Cliona McDowell; Mike Clarke; Fiona Copeland; Kathryn Ferguson; Rebecca H. McLeese; Rory Convery; Adam T. Hill; Anthony De Soyza; Mitra Shahidi; Martin Kelly; Mary Carroll; Timothy Gatheral; Muhammed Anwar; Jamie Duckers; William Flight; John R. Hurst; A Alina Ionescu; Michael R. Loebinger; Anita L. Sullivan; James D. Chalmers; Damian G. Downey; Michael M. Tunney; Brenda O'Neill; Daniel F. McAuley; J Stuart Elborn; Judy M. Bradley; Clifford C. Taggart

doi:10.1183/23120541.00202-2026

Effects of hypertonic saline and/or carbocisteine on sputum rheology in bronchiectasis (CLEAR-EME)

Michael C. McKelvey
, Gisli G. Einarsson
, Jack Carson
, Aram Kadoom
, Ryan R. Brown
, Christina Campbell
, Andrew Jackson
, Cliona McDowell
, Mike Clarke
, Fiona Copeland
, Kathryn Ferguson
, Rebecca H. McLeese
, Rory Convery
, Adam T. Hill
, Anthony De Soyza
, Mitra Shahidi
, Martin Kelly
, Mary Carroll
, Timothy Gatheral
, Muhammed Anwar

Jamie Duckers, William Flight, John R. Hurst, A Alina Ionescu, Michael R. Loebinger, Anita L. Sullivan, James D. Chalmers, Damian G. Downey, Michael M. Tunney, Brenda O'Neill, Daniel F. McAuley, J Stuart Elborn, Judy M. Bradley, Clifford C. Taggart

Research output: Contribution to journal › Article › peer-review

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Original language	English
Pages (from-to)	00202-2026
Journal	ERJ Open Research
DOIs	https://doi.org/10.1183/23120541.00202-2026
Publication status	Published (in print/issue) - 16 Apr 2026

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SDG 3 Good Health and Well-being

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10.1183/23120541.00202-2026Licence: CC BY

ERJ Open Res-2026-McKelvey-23120541.00202-2026Final published version, 1.91 MBLicence: CC BY

Cite this

McKelvey, M. C., Einarsson, G. G., Carson, J., Kadoom, A., Brown, R. R., Campbell, C., Jackson, A., McDowell, C., Clarke, M., Copeland, F., Ferguson, K., McLeese, R. H., Convery, R., Hill, A. T., De Soyza, A., Shahidi, M., Kelly, M., Carroll, M., Gatheral, T., ... Taggart, C. C. (2026). Effects of hypertonic saline and/or carbocisteine on sputum rheology in bronchiectasis (CLEAR-EME). ERJ Open Research, 00202-2026. https://doi.org/10.1183/23120541.00202-2026

@article{18e2d68a71f74957870f54bc40a7f1af,

title = "Effects of hypertonic saline and/or carbocisteine on sputum rheology in bronchiectasis (CLEAR-EME)",

author = "McKelvey, \{Michael C.\} and Einarsson, \{Gisli G.\} and Jack Carson and Aram Kadoom and Brown, \{Ryan R.\} and Christina Campbell and Andrew Jackson and Cliona McDowell and Mike Clarke and Fiona Copeland and Kathryn Ferguson and McLeese, \{Rebecca H.\} and Rory Convery and Hill, \{Adam T.\} and \{De Soyza\}, Anthony and Mitra Shahidi and Martin Kelly and Mary Carroll and Timothy Gatheral and Muhammed Anwar and Jamie Duckers and William Flight and Hurst, \{John R.\} and Ionescu, \{A Alina\} and Loebinger, \{Michael R.\} and Sullivan, \{Anita L.\} and Chalmers, \{James D.\} and Downey, \{Damian G.\} and Tunney, \{Michael M.\} and Brenda O'Neill and McAuley, \{Daniel F.\} and Elborn, \{J Stuart\} and Bradley, \{Judy M.\} and Taggart, \{Clifford C.\}",

year = "2026",

month = apr,

day = "16",

doi = "10.1183/23120541.00202-2026",

language = "English",

pages = "00202--2026",

journal = "ERJ Open Research",

issn = "2312-0541",

publisher = "European Respiratory Society",

}

McKelvey, MC, Einarsson, GG, Carson, J, Kadoom, A, Brown, RR, Campbell, C, Jackson, A, McDowell, C, Clarke, M, Copeland, F, Ferguson, K, McLeese, RH, Convery, R, Hill, AT, De Soyza, A, Shahidi, M, Kelly, M, Carroll, M, Gatheral, T, Anwar, M, Duckers, J, Flight, W, Hurst, JR, Ionescu, AA, Loebinger, MR, Sullivan, AL, Chalmers, JD, Downey, DG, Tunney, MM, O'Neill, B, McAuley, DF, Elborn, JS, Bradley, JM & Taggart, CC 2026, 'Effects of hypertonic saline and/or carbocisteine on sputum rheology in bronchiectasis (CLEAR-EME)', ERJ Open Research, pp. 00202-2026. https://doi.org/10.1183/23120541.00202-2026

TY - JOUR

T1 - Effects of hypertonic saline and/or carbocisteine on sputum rheology in bronchiectasis (CLEAR-EME)

AU - McKelvey, Michael C.

AU - Einarsson, Gisli G.

AU - Carson, Jack

AU - Kadoom, Aram

AU - Brown, Ryan R.

AU - Campbell, Christina

AU - Jackson, Andrew

AU - McDowell, Cliona

AU - Clarke, Mike

AU - Copeland, Fiona

AU - Ferguson, Kathryn

AU - McLeese, Rebecca H.

AU - Convery, Rory

AU - Hill, Adam T.

AU - De Soyza, Anthony

AU - Shahidi, Mitra

AU - Kelly, Martin

AU - Carroll, Mary

AU - Gatheral, Timothy

AU - Anwar, Muhammed

AU - Duckers, Jamie

AU - Flight, William

AU - Hurst, John R.

AU - Ionescu, A Alina

AU - Loebinger, Michael R.

AU - Sullivan, Anita L.

AU - Chalmers, James D.

AU - Downey, Damian G.

AU - Tunney, Michael M.

AU - O'Neill, Brenda

AU - McAuley, Daniel F.

AU - Elborn, J Stuart

AU - Bradley, Judy M.

AU - Taggart, Clifford C.

PY - 2026/4/16

Y1 - 2026/4/16

U2 - 10.1183/23120541.00202-2026

DO - 10.1183/23120541.00202-2026

M3 - Article

SN - 2312-0541

SP - 202

EP - 2026

JO - ERJ Open Research

JF - ERJ Open Research

ER -