Doxorubicin In Vivo Rapidly Alters Expression and Translation of Myocardial Electron Transport Chain Genes, Leads to ATP Loss and Caspase 3 Activation

Amy V. Pointon, Tracy M. Walker, Kate M. Phillips, Jinli Luo, Joan Riley, Shu-Dong Zhang, Joel D. Parry, Jonathan J. Lyon, Emma L. Marczylo, Timothy W. Gant

Research output: Contribution to journalArticle

72 Citations (Scopus)
LanguageEnglish
Pagese12733
JournalPLoS ONE
Volume5
Issue number9
DOIs
Publication statusPublished - 2010

Keywords

  • Doxorubicin
  • Myocardial Electron Transport Chain Genes
  • ATP Loss
  • Caspase 3 Activation
  • cardiotoxicity

Cite this

Pointon, Amy V. ; Walker, Tracy M. ; Phillips, Kate M. ; Luo, Jinli ; Riley, Joan ; Zhang, Shu-Dong ; Parry, Joel D. ; Lyon, Jonathan J. ; Marczylo, Emma L. ; Gant, Timothy W. / Doxorubicin In Vivo Rapidly Alters Expression and Translation of Myocardial Electron Transport Chain Genes, Leads to ATP Loss and Caspase 3 Activation. In: PLoS ONE. 2010 ; Vol. 5, No. 9. pp. e12733.
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title = "Doxorubicin In Vivo Rapidly Alters Expression and Translation of Myocardial Electron Transport Chain Genes, Leads to ATP Loss and Caspase 3 Activation",
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Doxorubicin In Vivo Rapidly Alters Expression and Translation of Myocardial Electron Transport Chain Genes, Leads to ATP Loss and Caspase 3 Activation. / Pointon, Amy V.; Walker, Tracy M.; Phillips, Kate M.; Luo, Jinli; Riley, Joan; Zhang, Shu-Dong; Parry, Joel D.; Lyon, Jonathan J.; Marczylo, Emma L.; Gant, Timothy W.

In: PLoS ONE, Vol. 5, No. 9, 2010, p. e12733.

Research output: Contribution to journalArticle

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AU - Pointon, Amy V.

AU - Walker, Tracy M.

AU - Phillips, Kate M.

AU - Luo, Jinli

AU - Riley, Joan

AU - Zhang, Shu-Dong

AU - Parry, Joel D.

AU - Lyon, Jonathan J.

AU - Marczylo, Emma L.

AU - Gant, Timothy W.

PY - 2010

Y1 - 2010

KW - Doxorubicin

KW - Myocardial Electron Transport Chain Genes

KW - ATP Loss

KW - Caspase 3 Activation

KW - cardiotoxicity

U2 - 10.1371/journal.pone.0012733

DO - 10.1371/journal.pone.0012733

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JO - PLoS ONE

T2 - PLoS ONE

JF - PLoS ONE

SN - 1932-6203

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