Dimension Reduction and Dynamics of a Spiking Neural Network Model for Decision Making under Neuromodulation

Philip Eckhoff, KongFatt Wong-Lin, Philip Holmes

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Previous models of neuromodulation in cortical circuits have used either physiologically based networks of spiking neurons or simplified gain adjustments in low-dimensional connectionist models. Here we reduce a high-dimensional spiking neuronal network model, first to a four-population mean-field model and then to a two-population model. This provides a realistic implementation of neuromodulation in low-dimensional decision-making models, speeds up simulations by three orders of magnitude, and allows bifurcation and phase-plane analyses of the reduced models that illuminate neuromodulatory mechanisms. As modulation of excitation-inhibition varies, the network can move from unaroused states, through optimal performance to impulsive states, and eventually lose inhibition-driven winner-take-all behavior: all are clear outcomes of the bifurcation structure. We illustrate the value of reduced models by a study of the speed-accuracy tradeoff in decision making. The ability of such models to recreate neuromodulatory dynamics of the spiking network will accelerate the pace of future experiments linking behavioral data to cellular neurophysiology.
LanguageEnglish
Pages148-188
JournalSIAM Journal on Applied Dynamical Systems
Volume10
Issue number1
DOIs
Publication statusPublished - 22 Feb 2011

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spiking
decision making
neurophysiology
tradeoffs
neurons
adjusting
modulation

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Dimension Reduction and Dynamics of a Spiking Neural Network Model for Decision Making under Neuromodulation. / Eckhoff, Philip; Wong-Lin, KongFatt; Holmes, Philip.

In: SIAM Journal on Applied Dynamical Systems, Vol. 10, No. 1, 22.02.2011, p. 148-188.

Research output: Contribution to journalArticle

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