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Digital exercise interventions to improve physical functioning of people with breast cancer: Protocol for a scoping review

  • Katherine A. Mankelow
  • , Sean O’Connor
  • , Olinda Santin
  • , Nicole E. Blackburn
  • , Iseult M. Wilson
  • , LS Katrina Li (Editor)

Research output: Contribution to journalArticlepeer-review

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Abstract

Introduction: Breast cancer incidence rates are rising due to early detection, improved screening methods and advances in treatment options. As mortality rates reduce, there is a growing population living longer with treatment side-effects who require assistance. Prevalent issues arising after breast cancer treatment include pain, fatigue, lymphoedema and arm and shoulder mobility issues. Evidence demonstrates that upper limb exercises help reduce these common side effects and improve day-to-day functioning and quality of life. However, access to physiotherapy and rehabilitation services remains limited due to resource and access constraints. Despite a growing interest in digital health resources, little is known about the effectiveness of using digital exercise interventions to help resolve this problem. Methods and analysis: A scoping review of available literature will be undertaken to explore what digital or online prehabilitation or rehabilitation interventions exist for people with breast cancer that incorporate an exercise component aimed at improving physical function or mobility. Peer-reviewed studies in English will be eligible for inclusion. A systematic search of Medline ALL, Embase, CINAHL, and Web of Science will be conducted and any relevant grey literature form trusted sources will also be included in our review. The Arksey and O’Malley framework will be applied together with updated guidance from other authors. To enhance rigour, the Joanna Briggs Institute methodology for scoping reviews will also be used to ensure accurate reporting. Articles will be screened by title and abstract against eligibility criteria before independent full text screening by two researchers. Arising conflicts will be resolved by consulting a third reviewer. To summarise the available evidence, data will be extracted using a tailored charting template and a descriptive narrative synthesis will follow. Ethics and dissemination: As this research involves the analysis of already published, peer-reviewed literature, ethical approval is not required. The results of this scoping review will be submitted for publication in a peer-reviewed journal. Any significant deviations from the original protocol will be transparently reported and justified.
Original languageEnglish
Article numbere0350300
Pages (from-to)1-8
Number of pages8
JournalPLoS One
Volume21
Issue number6
Early online date1 Jun 2026
DOIs
Publication statusPublished online - 1 Jun 2026

Bibliographical note

Publisher Copyright:
© 2026 Mankelow et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

Data Availability Statement

This paper reports
a study protocol. No data have yet been gen
erated. All data resulting from the completed
review will be made fully available in a public
repository at the time of publication.

Funding

The Department for the Economy (DfE) in Northern Ireland - CAST (Co-operative Awards in Science and Technology) Studentship.

Funders
Department for the Economy

    UN SDGs

    This output contributes to the following UN Sustainable Development Goals (SDGs)

    1. SDG 3 - Good Health and Well-being
      SDG 3 Good Health and Well-being

    Keywords

    • Breast Neoplasms
    • Digital Health
    • Exercise
    • Exercise Therapy
    • Female
    • Humans
    • Quality of Life
    • Research Design
    • Scoping Reviews As Topic
    • Breast Neoplasms/rehabilitation
    • Scoping Reviews as Topic
    • Exercise Therapy/methods

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