Differential TERT promoter methylation and response to 5-aza-2'-deoxycytidine in acute myeloid leukemia cell lines: TERT expression, telomerase activity, telomere length, and cell death

K.A. Pettigrew, R.N. Armstrong, H.A.A. Colyer, S.-D. Zhang, I.M. Rea, R.E. Jones, D.M. Baird, K.I. Mills

    Research output: Contribution to journalArticle

    LanguageEnglish
    Pages768-780
    JournalGenes, Chromosomes and Cancer
    Volume51
    Issue number8
    DOIs
    Publication statusPublished - 2012

    Keywords

    • EMTREE drug terms: 5 aza 2' deoxycytidine
    • messenger RNA
    • telomerase reverse transcriptase
    • EMTREE medical terms: acute granulocytic leukemia
    • aged
    • article
    • cancer patient
    • cancer resistance
    • cell death
    • cell strain HL 60
    • cell strain U937
    • cell viability
    • clinical article
    • controlled study
    • CpG island
    • demethylation
    • DNA methylation
    • DNA sequence
    • enzyme activity
    • female
    • gene expression
    • genetic parameters
    • human
    • human cell
    • leukemia cell
    • lymphoma cell
    • male
    • priority journal
    • promoter region
    • protein expression
    • pyrosequencing
    • telomere length
    • MeSH: Aged
    • 80 and over
    • Antimetabolites
    • Antineoplastic
    • Azacitidine
    • Cell Death
    • Cell Line
    • Tumor
    • CpG Islands
    • DNA Methylation
    • Female
    • Gene Expression Regulation
    • Neoplastic
    • HL-60 Cells
    • Humans
    • Leukemia
    • Myeloid
    • Acute
    • Male
    • Promoter Regions
    • Genetic
    • Telomerase
    • Telomere
    • U937 Cells

    Cite this

    Pettigrew, K.A. ; Armstrong, R.N. ; Colyer, H.A.A. ; Zhang, S.-D. ; Rea, I.M. ; Jones, R.E. ; Baird, D.M. ; Mills, K.I. / Differential TERT promoter methylation and response to 5-aza-2'-deoxycytidine in acute myeloid leukemia cell lines: TERT expression, telomerase activity, telomere length, and cell death. In: Genes, Chromosomes and Cancer. 2012 ; Vol. 51, No. 8. pp. 768-780.
    @article{362a84b785ac41fc8c421d48573679b3,
    title = "Differential TERT promoter methylation and response to 5-aza-2'-deoxycytidine in acute myeloid leukemia cell lines: TERT expression, telomerase activity, telomere length, and cell death",
    keywords = "EMTREE drug terms: 5 aza 2' deoxycytidine, messenger RNA, telomerase reverse transcriptase, EMTREE medical terms: acute granulocytic leukemia, aged, article, cancer patient, cancer resistance, cell death, cell strain HL 60, cell strain U937, cell viability, clinical article, controlled study, CpG island, demethylation, DNA methylation, DNA sequence, enzyme activity, female, gene expression, genetic parameters, human, human cell, leukemia cell, lymphoma cell, male, priority journal, promoter region, protein expression, pyrosequencing, telomere length, MeSH: Aged, 80 and over, Antimetabolites, Antineoplastic, Azacitidine, Cell Death, Cell Line, Tumor, CpG Islands, DNA Methylation, Female, Gene Expression Regulation, Neoplastic, HL-60 Cells, Humans, Leukemia, Myeloid, Acute, Male, Promoter Regions, Genetic, Telomerase, Telomere, U937 Cells",
    author = "K.A. Pettigrew and R.N. Armstrong and H.A.A. Colyer and S.-D. Zhang and I.M. Rea and R.E. Jones and D.M. Baird and K.I. Mills",
    note = "cited By 14",
    year = "2012",
    doi = "10.1002/gcc.21962",
    language = "English",
    volume = "51",
    pages = "768--780",
    journal = "Genes, Chromosomes and Cancer",
    issn = "1045-2257",
    number = "8",

    }

    Differential TERT promoter methylation and response to 5-aza-2'-deoxycytidine in acute myeloid leukemia cell lines: TERT expression, telomerase activity, telomere length, and cell death. / Pettigrew, K.A.; Armstrong, R.N.; Colyer, H.A.A.; Zhang, S.-D.; Rea, I.M.; Jones, R.E.; Baird, D.M.; Mills, K.I.

    In: Genes, Chromosomes and Cancer, Vol. 51, No. 8, 2012, p. 768-780.

    Research output: Contribution to journalArticle

    TY - JOUR

    T1 - Differential TERT promoter methylation and response to 5-aza-2'-deoxycytidine in acute myeloid leukemia cell lines: TERT expression, telomerase activity, telomere length, and cell death

    AU - Pettigrew, K.A.

    AU - Armstrong, R.N.

    AU - Colyer, H.A.A.

    AU - Zhang, S.-D.

    AU - Rea, I.M.

    AU - Jones, R.E.

    AU - Baird, D.M.

    AU - Mills, K.I.

    N1 - cited By 14

    PY - 2012

    Y1 - 2012

    KW - EMTREE drug terms: 5 aza 2' deoxycytidine

    KW - messenger RNA

    KW - telomerase reverse transcriptase

    KW - EMTREE medical terms: acute granulocytic leukemia

    KW - aged

    KW - article

    KW - cancer patient

    KW - cancer resistance

    KW - cell death

    KW - cell strain HL 60

    KW - cell strain U937

    KW - cell viability

    KW - clinical article

    KW - controlled study

    KW - CpG island

    KW - demethylation

    KW - DNA methylation

    KW - DNA sequence

    KW - enzyme activity

    KW - female

    KW - gene expression

    KW - genetic parameters

    KW - human

    KW - human cell

    KW - leukemia cell

    KW - lymphoma cell

    KW - male

    KW - priority journal

    KW - promoter region

    KW - protein expression

    KW - pyrosequencing

    KW - telomere length

    KW - MeSH: Aged

    KW - 80 and over

    KW - Antimetabolites

    KW - Antineoplastic

    KW - Azacitidine

    KW - Cell Death

    KW - Cell Line

    KW - Tumor

    KW - CpG Islands

    KW - DNA Methylation

    KW - Female

    KW - Gene Expression Regulation

    KW - Neoplastic

    KW - HL-60 Cells

    KW - Humans

    KW - Leukemia

    KW - Myeloid

    KW - Acute

    KW - Male

    KW - Promoter Regions

    KW - Genetic

    KW - Telomerase

    KW - Telomere

    KW - U937 Cells

    U2 - 10.1002/gcc.21962

    DO - 10.1002/gcc.21962

    M3 - Article

    VL - 51

    SP - 768

    EP - 780

    JO - Genes, Chromosomes and Cancer

    T2 - Genes, Chromosomes and Cancer

    JF - Genes, Chromosomes and Cancer

    SN - 1045-2257

    IS - 8

    ER -