Differential TERT promoter methylation and response to 5-aza-2′-deoxycytidine in acute myeloid leukemia cell lines: TERT expression, telomerase activity, telomere length, and cell death

Kerry A. Pettigrew; Richard N. Armstrong; Hilary A. A. Colyer; Shu-Dong Zhang; Irene Maeve Rea; Rhiannon E. Jones; Duncan M. Baird; Ken I. Mills

doi:10.1002/gcc.21962

Differential TERT promoter methylation and response to 5-aza-2′-deoxycytidine in acute myeloid leukemia cell lines: TERT expression, telomerase activity, telomere length, and cell death

Kerry A. Pettigrew
, Richard N. Armstrong
, Hilary A. A. Colyer
, Shu-Dong Zhang
, Irene Maeve Rea
, Rhiannon E. Jones
, Duncan M. Baird
, Ken I. Mills

Faculty Of Life & Health Sciences

Research output: Contribution to journal › Article › peer-review

29 Citations (Scopus)

Original language	English
Pages (from-to)	768-780
Journal	Genes, Chromosomes and Cancer
Volume	51
Issue number	8
DOIs	https://doi.org/10.1002/gcc.21962
Publication status	Published (in print/issue) - 2012

Bibliographical note

cited By 14

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

EMTREE drug terms: 5 aza 2' deoxycytidine
messenger RNA
telomerase reverse transcriptase
EMTREE medical terms: acute granulocytic leukemia
aged
article
cancer patient
cancer resistance
cell death
cell strain HL 60
cell strain U937
cell viability
clinical article
controlled study
CpG island
demethylation
DNA methylation
DNA sequence
enzyme activity
female
gene expression
genetic parameters
human
human cell
leukemia cell
lymphoma cell
male
priority journal
promoter region
protein expression
pyrosequencing
telomere length
MeSH: Aged
80 and over
Antimetabolites
Antineoplastic
Azacitidine
Cell Death
Cell Line
Tumor
CpG Islands
DNA Methylation
Female
Gene Expression Regulation
Neoplastic
HL-60 Cells
Humans
Leukemia
Myeloid
Acute
Male
Promoter Regions
Genetic
Telomerase
Telomere
U937 Cells

Access to Document

10.1002/gcc.21962

https://www.scopus.com/inward/record.uri?eid=2-s2.0-84861661655&doi=10.1002%2fgcc.21962&partnerID=40&md5=30af12678487ae9b3f487cec75bed9df

Cite this

Pettigrew, K. A., Armstrong, R. N., Colyer, H. A. A., Zhang, S.-D., Rea, I. M., Jones, R. E., Baird, D. M., & Mills, K. I. (2012). Differential TERT promoter methylation and response to 5-aza-2′-deoxycytidine in acute myeloid leukemia cell lines: TERT expression, telomerase activity, telomere length, and cell death. Genes, Chromosomes and Cancer, 51(8), 768-780. https://doi.org/10.1002/gcc.21962

@article{f2f7c9b6aaf34a58a0a1e9cdf800922e,

title = "Differential TERT promoter methylation and response to 5-aza-2′-deoxycytidine in acute myeloid leukemia cell lines: TERT expression, telomerase activity, telomere length, and cell death",

keywords = "EMTREE drug terms: 5 aza 2' deoxycytidine, messenger RNA, telomerase reverse transcriptase, EMTREE medical terms: acute granulocytic leukemia, aged, article, cancer patient, cancer resistance, cell death, cell strain HL 60, cell strain U937, cell viability, clinical article, controlled study, CpG island, demethylation, DNA methylation, DNA sequence, enzyme activity, female, gene expression, genetic parameters, human, human cell, leukemia cell, lymphoma cell, male, priority journal, promoter region, protein expression, pyrosequencing, telomere length, MeSH: Aged, 80 and over, Antimetabolites, Antineoplastic, Azacitidine, Cell Death, Cell Line, Tumor, CpG Islands, DNA Methylation, Female, Gene Expression Regulation, Neoplastic, HL-60 Cells, Humans, Leukemia, Myeloid, Acute, Male, Promoter Regions, Genetic, Telomerase, Telomere, U937 Cells",

author = "Pettigrew, \{Kerry A.\} and Armstrong, \{Richard N.\} and Colyer, \{Hilary A. A.\} and Shu-Dong Zhang and Rea, \{Irene Maeve\} and Jones, \{Rhiannon E.\} and Baird, \{Duncan M.\} and Mills, \{Ken I.\}",

note = "cited By 14",

year = "2012",

doi = "10.1002/gcc.21962",

language = "English",

volume = "51",

pages = "768--780",

journal = "Genes, Chromosomes and Cancer",

issn = "1098-2264",

publisher = "Wiley-Liss Inc.",

number = "8",

}

Pettigrew, KA, Armstrong, RN, Colyer, HAA, Zhang, S-D, Rea, IM, Jones, RE, Baird, DM & Mills, KI 2012, 'Differential TERT promoter methylation and response to 5-aza-2′-deoxycytidine in acute myeloid leukemia cell lines: TERT expression, telomerase activity, telomere length, and cell death', Genes, Chromosomes and Cancer, vol. 51, no. 8, pp. 768-780. https://doi.org/10.1002/gcc.21962

Differential TERT promoter methylation and response to 5-aza-2′-deoxycytidine in acute myeloid leukemia cell lines: TERT expression, telomerase activity, telomere length, and cell death. / Pettigrew, Kerry A.; Armstrong, Richard N.; Colyer, Hilary A. A. et al.
In: Genes, Chromosomes and Cancer, Vol. 51, No. 8, 2012, p. 768-780.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Differential TERT promoter methylation and response to 5-aza-2′-deoxycytidine in acute myeloid leukemia cell lines: TERT expression, telomerase activity, telomere length, and cell death

AU - Pettigrew, Kerry A.

AU - Armstrong, Richard N.

AU - Colyer, Hilary A. A.

AU - Zhang, Shu-Dong

AU - Rea, Irene Maeve

AU - Jones, Rhiannon E.

AU - Baird, Duncan M.

AU - Mills, Ken I.

N1 - cited By 14

PY - 2012

Y1 - 2012

KW - EMTREE drug terms: 5 aza 2' deoxycytidine

KW - messenger RNA

KW - telomerase reverse transcriptase

KW - EMTREE medical terms: acute granulocytic leukemia

KW - aged

KW - article

KW - cancer patient

KW - cancer resistance

KW - cell death

KW - cell strain HL 60

KW - cell strain U937

KW - cell viability

KW - clinical article

KW - controlled study

KW - CpG island

KW - demethylation

KW - DNA methylation

KW - DNA sequence

KW - enzyme activity

KW - female

KW - gene expression

KW - genetic parameters

KW - human

KW - human cell

KW - leukemia cell

KW - lymphoma cell

KW - male

KW - priority journal

KW - promoter region

KW - protein expression

KW - pyrosequencing

KW - telomere length

KW - MeSH: Aged

KW - 80 and over

KW - Antimetabolites

KW - Antineoplastic

KW - Azacitidine

KW - Cell Death

KW - Cell Line

KW - Tumor

KW - CpG Islands

KW - DNA Methylation

KW - Female

KW - Gene Expression Regulation

KW - Neoplastic

KW - HL-60 Cells

KW - Humans

KW - Leukemia

KW - Myeloid

KW - Acute

KW - Male

KW - Promoter Regions

KW - Genetic

KW - Telomerase

KW - Telomere

KW - U937 Cells

U2 - 10.1002/gcc.21962

DO - 10.1002/gcc.21962

M3 - Article

SN - 1098-2264

VL - 51

SP - 768

EP - 780

JO - Genes, Chromosomes and Cancer

JF - Genes, Chromosomes and Cancer

IS - 8

ER -