Abstract
| Language | English |
|---|---|
| Pages | 1186-1198 |
| Journal | ACS Sustainable Chemistry and Engineering |
| Volume | 5 |
| Issue number | 1 |
| Early online date | 22 Dec 2016 |
| DOIs | |
| Publication status | Published - 10 Jan 2017 |
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Keywords
- Starmerella bombicola
- Glycolipids
- Self-assembly
- Life cycle analysis
- Antimicrobial
- Genetic engineering
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Development of a Cradle-to-Grave Approach for Acetylated Acidic Sophorolipid Biosurfactants. / Mitchell, CA; Banat, Ibrahim; Marchant, R.
In: ACS Sustainable Chemistry and Engineering, Vol. 5, No. 1, 10.01.2017, p. 1186-1198.Research output: Contribution to journal › Article
TY - JOUR
T1 - Development of a Cradle-to-Grave Approach for Acetylated Acidic Sophorolipid Biosurfactants
AU - Mitchell, CA
AU - Banat, Ibrahim
AU - Marchant, R
N1 - Not compliant in UIR; not deposited within time frame
PY - 2017/1/10
Y1 - 2017/1/10
N2 - Microbial production of biosurfactants represents one of the most interesting alternatives to classical petrol-based compounds due to their low toxicity, high biodegradability, and biological production processes from renewable bioresources. However, some of the main drawbacksgenerally encountered are the low productivities and the small number of chemical structures available, which limit widespread application of biosurfactants. Although chemical derivatization of (microbial) biosurfactants offers opportunities to broaden the panel of available molecules, direct microbial synthesis is still the preferred option and the use of engineered strains is becoming a valid alternative. In this multidisciplinary work we show the entire process of conception, upscaling of fermentation (150 L) and sustainable purification (filtration), application (foaming, solubilization, antibacterial), and life cycle analysis of acetylated acidic sophorolipids, directly produced by the Starmerella bombicola esterase knock out yeast strain, rather than purified using chromatography from the classical, but complex, mixture of acidic and lactonic sophorolipids.
AB - Microbial production of biosurfactants represents one of the most interesting alternatives to classical petrol-based compounds due to their low toxicity, high biodegradability, and biological production processes from renewable bioresources. However, some of the main drawbacksgenerally encountered are the low productivities and the small number of chemical structures available, which limit widespread application of biosurfactants. Although chemical derivatization of (microbial) biosurfactants offers opportunities to broaden the panel of available molecules, direct microbial synthesis is still the preferred option and the use of engineered strains is becoming a valid alternative. In this multidisciplinary work we show the entire process of conception, upscaling of fermentation (150 L) and sustainable purification (filtration), application (foaming, solubilization, antibacterial), and life cycle analysis of acetylated acidic sophorolipids, directly produced by the Starmerella bombicola esterase knock out yeast strain, rather than purified using chromatography from the classical, but complex, mixture of acidic and lactonic sophorolipids.
KW - Starmerella bombicola
KW - Glycolipids
KW - Self-assembly
KW - Life cycle analysis
KW - Antimicrobial
KW - Genetic engineering
U2 - 10.1021/acssuschemeng.6b02570
DO - 10.1021/acssuschemeng.6b02570
M3 - Article
VL - 5
SP - 1186
EP - 1198
JO - ACS Sustainable Chemistry and Engineering
T2 - ACS Sustainable Chemistry and Engineering
JF - ACS Sustainable Chemistry and Engineering
SN - 2168-0485
IS - 1
ER -