Development of a Cradle-to-Grave Approach for Acetylated Acidic Sophorolipid Biosurfactants

CA Mitchell, Ibrahim Banat, R Marchant

Research output: Contribution to journal › Article

11 Citations (Scopus)

Abstract

Microbial production of biosurfactants represents one of the most interesting alternatives to classical petrol-based compounds due to their low toxicity, high biodegradability, and biological production processes from renewable bioresources. However, some of the main drawbacksgenerally encountered are the low productivities and the small number of chemical structures available, which limit widespread application of biosurfactants. Although chemical derivatization of (microbial) biosurfactants offers opportunities to broaden the panel of available molecules, direct microbial synthesis is still the preferred option and the use of engineered strains is becoming a valid alternative. In this multidisciplinary work we show the entire process of conception, upscaling of fermentation (150 L) and sustainable purification (filtration), application (foaming, solubilization, antibacterial), and life cycle analysis of acetylated acidic sophorolipids, directly produced by the Starmerella bombicola esterase knock out yeast strain, rather than purified using chromatography from the classical, but complex, mixture of acidic and lactonic sophorolipids.
LanguageEnglish
Pages1186-1198
JournalACS Sustainable Chemistry and Engineering
Volume5
Issue number1
Early online date22 Dec 2016
DOIs
Publication statusPublished - 10 Jan 2017

Fingerprint

life cycle analysis
biological production
upscaling
solubilization
chromatography
fermentation
yeast
purification
toxicity
productivity
chemical structure
chemical
biodegradability
petrol

Keywords

  • Starmerella bombicola
  • Glycolipids
  • Self-assembly
  • Life cycle analysis
  • Antimicrobial
  • Genetic engineering

Cite this

Mitchell, CA ; Banat, Ibrahim ; Marchant, R. / Development of a Cradle-to-Grave Approach for Acetylated Acidic Sophorolipid Biosurfactants. 2017 ; Vol. 5, No. 1. pp. 1186-1198.
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Mitchell, CA, Banat, I & Marchant, R 2017, 'Development of a Cradle-to-Grave Approach for Acetylated Acidic Sophorolipid Biosurfactants', vol. 5, no. 1, pp. 1186-1198. https://doi.org/10.1021/acssuschemeng.6b02570

Development of a Cradle-to-Grave Approach for Acetylated Acidic Sophorolipid Biosurfactants. / Mitchell, CA; Banat, Ibrahim; Marchant, R.

Vol. 5, No. 1, 10.01.2017, p. 1186-1198.

Research output: Contribution to journal › Article

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Mitchell CA, Banat I, Marchant R. Development of a Cradle-to-Grave Approach for Acetylated Acidic Sophorolipid Biosurfactants. 2017 Jan 10;5(1):1186-1198. https://doi.org/10.1021/acssuschemeng.6b02570

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