Design of a G-Quadruplex Topology through Glycosidic Bond Angles

Mateus Webba da Silva, Marko Trajkovski, Yuta Sannohe, Nason Hessari, Hiroshi Sugiyama, Janez Plavec

Research output: Contribution to journalArticle

41 Citations (Scopus)

Abstract

To realize a programmed build up of DNA objects, devices,and materials, a systematization of the principles that formthe basis of control for the assembly process is necessary. Thusfar the discovery of four-stranded DNA architecturesdenominated G quadruplexes was either serendipitous orthrough coincidental emergence. Herein we utilize a rationalapproach for the design of G quadruplexes based on the twostatedisposition of the glycosidic bond angle.
LanguageEnglish
JournalAngewandte Chemie International Edition
Volume48
DOIs
Publication statusPublished - 2009

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Topology
DNA

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Webba da Silva, Mateus ; Trajkovski, Marko ; Sannohe, Yuta ; Hessari, Nason ; Sugiyama, Hiroshi ; Plavec, Janez. / Design of a G-Quadruplex Topology through Glycosidic Bond Angles. In: Angewandte Chemie International Edition. 2009 ; Vol. 48.
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Design of a G-Quadruplex Topology through Glycosidic Bond Angles. / Webba da Silva, Mateus; Trajkovski, Marko; Sannohe, Yuta; Hessari, Nason; Sugiyama, Hiroshi; Plavec, Janez.

In: Angewandte Chemie International Edition, Vol. 48, 2009.

Research output: Contribution to journalArticle

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AU - Sugiyama, Hiroshi

AU - Plavec, Janez

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