Design of a G-Quadruplex Topology through Glycosidic Bond Angles

Mateus Webba da Silva; Marko Trajkovski; Yuta Sannohe; Nason Hessari; Hiroshi Sugiyama; Janez Plavec

doi:10.1002/anie.200902454

Design of a G-Quadruplex Topology through Glycosidic Bond Angles

Mateus Webba da Silva, Marko Trajkovski, Yuta Sannohe, Nason Hessari, Hiroshi Sugiyama, Janez Plavec

Research output: Contribution to journal › Article › peer-review

69 Citations (Scopus)

Abstract

To realize a programmed build up of DNA objects, devices,and materials, a systematization of the principles that formthe basis of control for the assembly process is necessary. Thusfar the discovery of four-stranded DNA architecturesdenominated G quadruplexes was either serendipitous orthrough coincidental emergence. Herein we utilize a rationalapproach for the design of G quadruplexes based on the twostatedisposition of the glycosidic bond angle.

Original language	English
Journal	Angewandte Chemie International Edition
Volume	48
DOIs	https://doi.org/10.1002/anie.200902454
Publication status	Published (in print/issue) - 2009

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http://www3.interscience.wiley.com/journal/26737/home/2002_authors.html

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title = "Design of a G-Quadruplex Topology through Glycosidic Bond Angles",

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AU - Hessari, Nason

AU - Sugiyama, Hiroshi

AU - Plavec, Janez

PY - 2009

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AB - To realize a programmed build up of DNA objects, devices,and materials, a systematization of the principles that formthe basis of control for the assembly process is necessary. Thusfar the discovery of four-stranded DNA architecturesdenominated G quadruplexes was either serendipitous orthrough coincidental emergence. Herein we utilize a rationalapproach for the design of G quadruplexes based on the twostatedisposition of the glycosidic bond angle.

U2 - 10.1002/anie.200902454

DO - 10.1002/anie.200902454

M3 - Article

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VL - 48

JO - Angewandte Chemie International Edition

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ER -

Design of a G-Quadruplex Topology through Glycosidic Bond Angles

Abstract

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