Design, Facile Synthesis, and Antibacterial Activity of Hybrid 1,3,4-thiadiazole-1,3,5-triazine Derivatives Tethered via -S- Bridge

Vaibhav Dubey; Manish Pathak; Hans R Bhat; Udaya P Singh

doi:10.1111/j.1747-0285.2012.01433.x

Design, Facile Synthesis, and Antibacterial Activity of Hybrid 1,3,4-thiadiazole-1,3,5-triazine Derivatives Tethered via -S- Bridge

Vaibhav Dubey, Manish Pathak, Hans R Bhat, Udaya P Singh

School of Biomedical Sciences

Research output: Contribution to journal › Article › peer-review

Abstract

Some hybrid 1,3,4-thiadiazole-1,3,5-triazine derivatives tethered via –S– bridge were synthesized and characterized with the aid of spectroscopic and elemental analysis. These hybrid conjugates were then investigated for their antibacterial activity against selected Gram-positive and Gram-negative bacteria. Excellent to moderate antibacterial activity was presented by the target compounds.

Original language	English
Pages (from-to)	598-604
Number of pages	7
Journal	Chemical Biology and Drug Design
Volume	80
Issue number	4
Early online date	20 Jun 2012
DOIs	https://doi.org/10.1111/j.1747-0285.2012.01433.x
Publication status	Published (in print/issue) - 31 Oct 2012

Keywords

1,3,4-thiadiazole
1,3,5-triazine
antibacterial
hybrid

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1111/j.1747-0285.2012.01433.x

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abstract = "Some hybrid 1,3,4-thiadiazole-1,3,5-triazine derivatives tethered via –S– bridge were synthesized and characterized with the aid of spectroscopic and elemental analysis. These hybrid conjugates were then investigated for their antibacterial activity against selected Gram-positive and Gram-negative bacteria. Excellent to moderate antibacterial activity was presented by the target compounds.",

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AU - Pathak, Manish

AU - Bhat, Hans R

AU - Singh, Udaya P

PY - 2012/10/31

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AB - Some hybrid 1,3,4-thiadiazole-1,3,5-triazine derivatives tethered via –S– bridge were synthesized and characterized with the aid of spectroscopic and elemental analysis. These hybrid conjugates were then investigated for their antibacterial activity against selected Gram-positive and Gram-negative bacteria. Excellent to moderate antibacterial activity was presented by the target compounds.

KW - 1,3,4-thiadiazole

KW - 1,3,5-triazine

KW - antibacterial

KW - hybrid

UR - http://dx.doi.org/10.1111/j.1747-0285.2012.01433.x

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M3 - Article

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ER -

Design, Facile Synthesis, and Antibacterial Activity of Hybrid 1,3,4-thiadiazole-1,3,5-triazine Derivatives Tethered via -S- Bridge

Abstract

Keywords

UN SDGs

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