Design, Facile Synthesis, and Antibacterial Activity of Hybrid 1,3,4-thiadiazole-1,3,5-triazine Derivatives Tethered via -S- Bridge: Antibacterial Activity of 1,3,5-triazines

Vaibhav Dubey, Manish Pathak, Hans R. Bhat, Udaya P. Singh

Research output: Contribution to journalArticlepeer-review

Abstract

Some hybrid 1,3,4-thiadiazole-1,3,5-triazine derivatives tethered via –S– bridge were synthesized and characterized with the aid of spectroscopic and elemental analysis. These hybrid conjugates were then investigated for their antibacterial
activity against selected Gram-positive and Gram-negative bacteria. Excellent to moderate antibacterial activity was presented by the target compounds.
Original languageEnglish
Pages (from-to)598-604
Number of pages7
JournalChemical Biology and Drug Design
Volume80
Issue number4
DOIs
Publication statusPublished - 1 Oct 2012

Keywords

  • 1,3,4-thiadiazole
  • 1,3,5-triazine
  • antibacterial
  • hybrid

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