Dendrimer based nanoarchitectures in diabetes management: An overview

Vijay Mishra, Nishika Yadav, Gaurav Saraogi, Murtaza M Tambuwala, Namita Giri

Research output: Contribution to journalReview article

1 Citation (Scopus)
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Abstract

Diabetes has turned out to be one of the biggest worldwide health and economic burdens, with its expanded predominance and high complexity proportion. The quantity of diabetic patients is expanding enormously around the world. Several reports have demonstrated the sharp increment in the sufferers. Stable and acceptable blood glucose control is fundamental to diminish diabetes-related complications. Consequently, ceaseless endeavors have been made in antidiabetic drugs, treatment strategies, and nanotechnology based products to accomplish better diabetes control. The nanocarriers pertaining hypoglycaemics provide improved diabetes management with minimum risk of associated side effects. Dendrimers have caught an incredible attention in the field of drug delivery and personalized medicines. Dendrimers are three-dimensional well-defined homogenous nanosized structures consisting tree-like branches. The present review highlights the different aspects of dendrimers including fabrication, surface engineering, toxicological profile as well as delivery of antidiabetic drugs for the effective cure of diabetes.
Original languageEnglish
Pages (from-to)2569-2583
Number of pages15
JournalCurrent Pharmaceutical Design
Volume25
Issue number23
Early online date18 Sep 2019
DOIs
Publication statusE-pub ahead of print - 18 Sep 2019

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Keywords

  • Diabetes
  • nanomedicine
  • Dendrimers
  • toxicity
  • dendrimer
  • nanocarrier
  • drug delivery
  • toxicological profile.
  • toxicological profile

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