Delivering Endothelial Keratoplasty Grafts: Modern Day Transplant Devices

Mohit Parekh, Vito Romano, Kareem Hassanin, Valeria Testa, Rintra Wongvisavavit, Stefano Ferrari, Colin Willoughby, Diego Ponzin, Vishal Jhanji, Namrata Sharma, Julie Daniels, Stephen B. Kaye, Sajjad Ahmad, Hannah Levis

Research output: Contribution to journalReview articlepeer-review

Abstract

Purpose
To summarize the graft loading, transporting and delivery devices used for endothelial keratoplasty (EK).
Methods
A literature search of electronic databases was performed.
Results
New techniques and devices have been introduced and implemented to prepare, load, transport and transplant the grafts for EK. The advantages are not only limited to the surgical theatre but also widely spread across the eye banking field. Investigation of advanced materials and designs have been rapidly growing with continuous evolution in the field of eye banking and corneal transplantation. Innovative techniques and modern devices have been evaluated to reduce the endothelial cell loss and increase the precision of the transplant in order to benefit both surgeons and the patients.
Conclusions
It is extremely important to reduce any potential wastage and optimize the use of every available donor cornea due to the limited availability of healthy cadaveric donor corneas required for transplants. As a result, the use of pre-cut and pre-loaded grafts supplied by the eye banks in calibrated devices have been gaining momentum. Innovation in the field of bioengineering for the development of new devices that facilitate excellent clinical outcomes along with reduction in learning curve has shown promising results.
Original languageEnglish
Pages (from-to)1-12
Number of pages12
JournalCurrent Eye Research
Early online date5 Jan 2022
DOIs
Publication statusE-pub ahead of print - 5 Jan 2022

Bibliographical note

Publisher Copyright:
© 2022 Taylor & Francis Group, LLC.

Keywords

  • Cellular and Molecular Neuroscience
  • Sensory Systems
  • Ophthalmology
  • endothelial keratoplasty
  • Cornea
  • devices
  • injectors
  • glides
  • DSAEK
  • DMEK

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