Convergence of multidrug resistance with biofilm formation and hypermucoviscosity in Klebsiella pneumoniae from tertiary-care hospitals in Northwestern Pakistan

Aiman Waheed; Taj Ali Khan; Sajjad Ahmad; Fahad Ahmed; Zahoor Khan

doi:10.1017/ash.2026.10405

Convergence of multidrug resistance with biofilm formation and hypermucoviscosity in Klebsiella pneumoniae from tertiary-care hospitals in Northwestern Pakistan

Aiman Waheed
, Taj Ali Khan
, Sajjad Ahmad
, Fahad Ahmed
, Zahoor Khan

Research output: Contribution to journal › Article › peer-review

6 Downloads (Pure)

Abstract

This multicenter study describes the convergence of multidrug resistance, biofilm formation, and hypermucoviscosity in Klebsiella pneumoniae clinical isolates from tertiary-care hospitals in Pakistan. The high prevalence of these phenotypes highlights significant therapeutic challenges and underscores the need for strengthened surveillance, infection control, and antimicrobial stewardship.

Original language	English
Article number	e143
Pages (from-to)	1-3
Number of pages	3
Journal	Antimicrobial Stewardship & Healthcare Epidemiology
Volume	6
Issue number	1
Early online date	13 May 2026
DOIs	https://doi.org/10.1017/ash.2026.10405
Publication status	Published online - 13 May 2026

Bibliographical note

Publisher Copyright:
© The Author(s), 2026. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America.

Rights Retention Statement

This Author Accepted Manuscript has been made open access under a Creative Commons Attribution 4.0 International licence (CC BY 4.0) under the terms of Ulster University Rights Retention Policy for Scholarly Works. To view a copy of this licence, visit https://creativecommons.org/licenses/by/4.0/.

Data Availability Statement

The data supporting the findings of this study are available within the article.

Funding

No external funding was received for the conduct of this research.

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being
SDG 11 Sustainable Cities and Communities
SDG 15 Life on Land
SDG 17 Partnerships for the Goals

Keywords

Klebsiella pneumoniae
multidrug-resistant
extensively drug-resistant
hypermucoviscosity
biofilm formation

Access to Document

10.1017/ash.2026.10405Licence: CC BY

Convergence of MDR R1Author Accepted Manuscript, 574 KBLicence: CC BY

Cite this

Waheed, A., Khan, T. A., Ahmad, S., Ahmed, F., & Khan, Z. (2026). Convergence of multidrug resistance with biofilm formation and hypermucoviscosity in Klebsiella pneumoniae from tertiary-care hospitals in Northwestern Pakistan. Antimicrobial Stewardship & Healthcare Epidemiology, 6(1), 1-3. Article e143. Advance online publication. https://doi.org/10.1017/ash.2026.10405

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abstract = "This multicenter study describes the convergence of multidrug resistance, biofilm formation, and hypermucoviscosity in Klebsiella pneumoniae clinical isolates from tertiary-care hospitals in Pakistan. The high prevalence of these phenotypes highlights significant therapeutic challenges and underscores the need for strengthened surveillance, infection control, and antimicrobial stewardship.",

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author = "Aiman Waheed and Khan, \{Taj Ali\} and Sajjad Ahmad and Fahad Ahmed and Zahoor Khan",

note = "Publisher Copyright: {\textcopyright} The Author(s), 2026. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America.",

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doi = "10.1017/ash.2026.10405",

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Convergence of multidrug resistance with biofilm formation and hypermucoviscosity in Klebsiella pneumoniae from tertiary-care hospitals in Northwestern Pakistan. / Waheed, Aiman; Khan, Taj Ali; Ahmad, Sajjad et al.
In: Antimicrobial Stewardship & Healthcare Epidemiology, Vol. 6, No. 1, e143, 13.05.2026, p. 1-3.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Convergence of multidrug resistance with biofilm formation and hypermucoviscosity in Klebsiella pneumoniae from tertiary-care hospitals in Northwestern Pakistan

AU - Waheed, Aiman

AU - Khan, Taj Ali

AU - Ahmad, Sajjad

AU - Ahmed, Fahad

AU - Khan, Zahoor

PY - 2026/5/13

Y1 - 2026/5/13

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AB - This multicenter study describes the convergence of multidrug resistance, biofilm formation, and hypermucoviscosity in Klebsiella pneumoniae clinical isolates from tertiary-care hospitals in Pakistan. The high prevalence of these phenotypes highlights significant therapeutic challenges and underscores the need for strengthened surveillance, infection control, and antimicrobial stewardship.

KW - Klebsiella pneumoniae

KW - multidrug-resistant

KW - extensively drug-resistant

KW - hypermucoviscosity

KW - biofilm formation

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DO - 10.1017/ash.2026.10405

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JO - Antimicrobial Stewardship & Healthcare Epidemiology

JF - Antimicrobial Stewardship & Healthcare Epidemiology

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ER -

Convergence of multidrug resistance with biofilm formation and hypermucoviscosity in Klebsiella pneumoniae from tertiary-care hospitals in Northwestern Pakistan

Abstract

Bibliographical note

Rights Retention Statement

Data Availability Statement

Funding

UN SDGs

Keywords

Access to Document

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