Consideration-of-concept of EvolvRehab-Body for upper limb virtual rehabilitation at home for people late after stroke.

Fiona Ellis; Nicola Hancock; Niamh Kennedy; Allan Clark; Jacob Wells; Elizabeth Chandler; David Payne; Valerie Pomeroy

doi:10.1016/j.physio.2022.03.004

Consideration-of-concept of EvolvRehab-Body for upper limb virtual rehabilitation at home for people late after stroke.

Fiona Ellis
, Nicola Hancock
, Niamh Kennedy
, Allan Clark
, Jacob Wells
, Elizabeth Chandler
, David Payne
, Valerie Pomeroy

University of East Anglia

Research output: Contribution to journal › Article › peer-review

8 Citations (Scopus)

37 Downloads (Pure)

Abstract

Objective
EvolvRehab-Body is a non-immersive virtual rehabilitation system that could provide high-dose, exercise-based upper limb therapy after stroke. This consideration-of-concept study investigated: adherence rate to prescribed repetitions; viability of repeated measures in preparation for a dose-articulation study; and preliminary signal of potential benefit.

Methods
Pre-post and repeated measures with people at least six months after stroke. Twelve-week intervention: exercise-based therapy via EvolvRehab-Body. Pre-post-intervention measures: Wolf Motor Function Test (WMFT); hand grip force. Repeated-during-intervention measures: Motricity Index (MI) and Action Research Arm Test (ARAT). Analysis: adherence rate (%) to set repetitions; percentage of total possible measures collected; pre-to-post-intervention change estimated in relation to published minimally detectable changes of WMFT and hand grip force; and slope of plotted data for MI and ARAT (linear regression).

Results
Eight of twelve participants completed the 12-week intervention phase. Adherence: 88% (1710–9377 repetitions performed). Viability repeated measures: 88 of 96 (92%) ARAT and MI scores collected. Preliminary signal of potential benefit was observed in five participants but not always for the same measures. Three participants improved WMFT-time (−7.9 to −27.2 s/item), four improved WMFT-function (0.2–1.1 points/item), and nobody changed grip force. Slope of plotted data over the 12-week intervention ranged from: − 1.42 (p = 0.26) to 1.36 (p = 0.24) points-per-week for MI and − 0.30 (p = 0.40) to 1.71 (p < 0.001) points-per-week for ARAT.

Conclusion
Findings of good adherence rate in home settings and preliminary signal of benefit for some participants gives support to proceed to a dose-articulation study. These findings cannot inform clinical practice.

Original language	English
Pages (from-to)	97-107
Number of pages	11
Journal	Physiotherapy
Volume	116
Early online date	8 Apr 2022
DOIs	https://doi.org/10.1016/j.physio.2022.03.004
Publication status	Published (in print/issue) - 1 Sept 2022

Bibliographical note

Funding Information:
We are grateful to Evolv Rehabilitation Technologies for providing part of the funding of the University of East Anglia PhD studentship held by Fiona Ellis, first author of this scientific report. We are also grateful for the support for the last author’s research provided by the National Institute for Health Research (NIHR) Brain Injury MedTech Co-operative based at Cambridge University Hospitals NHS Foundation Trust and University of Cambridge. The views expressed are those of the authors and not necessarily those of the NHS, the NIHR or the Department of Health and Social Care.

Funding Information:
Fiona Ellis was funded by a University of East Anglia (UEA) PhD Fellowship. Funding for the PhD Fellowship was provided by the UEA and Evolv Rehabilitation Technologies.

Publisher Copyright:
© 2022 Chartered Society of Physiotherapy

Funding

Funding Information: We are grateful to Evolv Rehabilitation Technologies for providing part of the funding of the University of East Anglia PhD studentship held by Fiona Ellis, first author of this scientific report. We are also grateful for the support for the last author’s research provided by the National Institute for Health Research (NIHR) Brain Injury MedTech Co-operative based at Cambridge University Hospitals NHS Foundation Trust and University of Cambridge. The views expressed are those of the authors and not necessarily those of the NHS, the NIHR or the Department of Health and Social Care. Funding Information: Fiona Ellis was funded by a University of East Anglia (UEA) PhD Fellowship. Funding for the PhD Fellowship was provided by the UEA and Evolv Rehabilitation Technologies. Publisher Copyright: © 2022 Chartered Society of Physiotherapy

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Virtual Rehabilitation
Virtual Reality
User-led design
Stroke

Access to Document

10.1016/j.physio.2022.03.004

Manuscript Accepted Version Ellis et al R1Author Accepted Manuscript, 7.17 MB

Cite this

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title = "Consideration-of-concept of EvolvRehab-Body for upper limb virtual rehabilitation at home for people late after stroke.",

abstract = "Objective EvolvRehab-Body is a non-immersive virtual rehabilitation system that could provide high-dose, exercise-based upper limb therapy after stroke. This consideration-of-concept study investigated: adherence rate to prescribed repetitions; viability of repeated measures in preparation for a dose-articulation study; and preliminary signal of potential benefit. Methods Pre-post and repeated measures with people at least six months after stroke. Twelve-week intervention: exercise-based therapy via EvolvRehab-Body. Pre-post-intervention measures: Wolf Motor Function Test (WMFT); hand grip force. Repeated-during-intervention measures: Motricity Index (MI) and Action Research Arm Test (ARAT). Analysis: adherence rate (\%) to set repetitions; percentage of total possible measures collected; pre-to-post-intervention change estimated in relation to published minimally detectable changes of WMFT and hand grip force; and slope of plotted data for MI and ARAT (linear regression). Results Eight of twelve participants completed the 12-week intervention phase. Adherence: 88\% (1710–9377 repetitions performed). Viability repeated measures: 88 of 96 (92\%) ARAT and MI scores collected. Preliminary signal of potential benefit was observed in five participants but not always for the same measures. Three participants improved WMFT-time (−7.9 to −27.2 s/item), four improved WMFT-function (0.2–1.1 points/item), and nobody changed grip force. Slope of plotted data over the 12-week intervention ranged from: − 1.42 (p = 0.26) to 1.36 (p = 0.24) points-per-week for MI and − 0.30 (p = 0.40) to 1.71 (p < 0.001) points-per-week for ARAT. Conclusion Findings of good adherence rate in home settings and preliminary signal of benefit for some participants gives support to proceed to a dose-articulation study. These findings cannot inform clinical practice.",

keywords = "Virtual Rehabilitation, Virtual Reality, User-led design, Stroke",

author = "Fiona Ellis and Nicola Hancock and Niamh Kennedy and Allan Clark and Jacob Wells and Elizabeth Chandler and David Payne and Valerie Pomeroy",

note = "Funding Information: We are grateful to Evolv Rehabilitation Technologies for providing part of the funding of the University of East Anglia PhD studentship held by Fiona Ellis, first author of this scientific report. We are also grateful for the support for the last author{\textquoteright}s research provided by the National Institute for Health Research (NIHR) Brain Injury MedTech Co-operative based at Cambridge University Hospitals NHS Foundation Trust and University of Cambridge. The views expressed are those of the authors and not necessarily those of the NHS, the NIHR or the Department of Health and Social Care. Funding Information: Fiona Ellis was funded by a University of East Anglia (UEA) PhD Fellowship. Funding for the PhD Fellowship was provided by the UEA and Evolv Rehabilitation Technologies. Publisher Copyright: {\textcopyright} 2022 Chartered Society of Physiotherapy",

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doi = "10.1016/j.physio.2022.03.004",

language = "English",

volume = "116",

pages = "97--107",

journal = "Physiotherapy",

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}

TY - JOUR

T1 - Consideration-of-concept of EvolvRehab-Body for upper limb virtual rehabilitation at home for people late after stroke.

AU - Ellis, Fiona

AU - Hancock, Nicola

AU - Kennedy, Niamh

AU - Clark, Allan

AU - Wells, Jacob

AU - Chandler, Elizabeth

AU - Payne, David

AU - Pomeroy, Valerie

N1 - Funding Information: We are grateful to Evolv Rehabilitation Technologies for providing part of the funding of the University of East Anglia PhD studentship held by Fiona Ellis, first author of this scientific report. We are also grateful for the support for the last author’s research provided by the National Institute for Health Research (NIHR) Brain Injury MedTech Co-operative based at Cambridge University Hospitals NHS Foundation Trust and University of Cambridge. The views expressed are those of the authors and not necessarily those of the NHS, the NIHR or the Department of Health and Social Care. Funding Information: Fiona Ellis was funded by a University of East Anglia (UEA) PhD Fellowship. Funding for the PhD Fellowship was provided by the UEA and Evolv Rehabilitation Technologies. Publisher Copyright: © 2022 Chartered Society of Physiotherapy

PY - 2022/9/1

Y1 - 2022/9/1

N2 - Objective EvolvRehab-Body is a non-immersive virtual rehabilitation system that could provide high-dose, exercise-based upper limb therapy after stroke. This consideration-of-concept study investigated: adherence rate to prescribed repetitions; viability of repeated measures in preparation for a dose-articulation study; and preliminary signal of potential benefit. Methods Pre-post and repeated measures with people at least six months after stroke. Twelve-week intervention: exercise-based therapy via EvolvRehab-Body. Pre-post-intervention measures: Wolf Motor Function Test (WMFT); hand grip force. Repeated-during-intervention measures: Motricity Index (MI) and Action Research Arm Test (ARAT). Analysis: adherence rate (%) to set repetitions; percentage of total possible measures collected; pre-to-post-intervention change estimated in relation to published minimally detectable changes of WMFT and hand grip force; and slope of plotted data for MI and ARAT (linear regression). Results Eight of twelve participants completed the 12-week intervention phase. Adherence: 88% (1710–9377 repetitions performed). Viability repeated measures: 88 of 96 (92%) ARAT and MI scores collected. Preliminary signal of potential benefit was observed in five participants but not always for the same measures. Three participants improved WMFT-time (−7.9 to −27.2 s/item), four improved WMFT-function (0.2–1.1 points/item), and nobody changed grip force. Slope of plotted data over the 12-week intervention ranged from: − 1.42 (p = 0.26) to 1.36 (p = 0.24) points-per-week for MI and − 0.30 (p = 0.40) to 1.71 (p < 0.001) points-per-week for ARAT. Conclusion Findings of good adherence rate in home settings and preliminary signal of benefit for some participants gives support to proceed to a dose-articulation study. These findings cannot inform clinical practice.

AB - Objective EvolvRehab-Body is a non-immersive virtual rehabilitation system that could provide high-dose, exercise-based upper limb therapy after stroke. This consideration-of-concept study investigated: adherence rate to prescribed repetitions; viability of repeated measures in preparation for a dose-articulation study; and preliminary signal of potential benefit. Methods Pre-post and repeated measures with people at least six months after stroke. Twelve-week intervention: exercise-based therapy via EvolvRehab-Body. Pre-post-intervention measures: Wolf Motor Function Test (WMFT); hand grip force. Repeated-during-intervention measures: Motricity Index (MI) and Action Research Arm Test (ARAT). Analysis: adherence rate (%) to set repetitions; percentage of total possible measures collected; pre-to-post-intervention change estimated in relation to published minimally detectable changes of WMFT and hand grip force; and slope of plotted data for MI and ARAT (linear regression). Results Eight of twelve participants completed the 12-week intervention phase. Adherence: 88% (1710–9377 repetitions performed). Viability repeated measures: 88 of 96 (92%) ARAT and MI scores collected. Preliminary signal of potential benefit was observed in five participants but not always for the same measures. Three participants improved WMFT-time (−7.9 to −27.2 s/item), four improved WMFT-function (0.2–1.1 points/item), and nobody changed grip force. Slope of plotted data over the 12-week intervention ranged from: − 1.42 (p = 0.26) to 1.36 (p = 0.24) points-per-week for MI and − 0.30 (p = 0.40) to 1.71 (p < 0.001) points-per-week for ARAT. Conclusion Findings of good adherence rate in home settings and preliminary signal of benefit for some participants gives support to proceed to a dose-articulation study. These findings cannot inform clinical practice.

KW - Virtual Rehabilitation

KW - Virtual Reality

KW - User-led design

KW - Stroke

UR - https://www.scopus.com/pages/publications/85130790678

U2 - 10.1016/j.physio.2022.03.004

DO - 10.1016/j.physio.2022.03.004

M3 - Article

SN - 0031-9406

VL - 116

SP - 97

EP - 107

JO - Physiotherapy

JF - Physiotherapy

ER -

Consideration-of-concept of EvolvRehab-Body for upper limb virtual rehabilitation at home for people late after stroke.

Abstract

Bibliographical note

Funding

UN SDGs

Keywords

Access to Document

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