Connectivity mapping using a combined gene signature from multiple colorectal cancer datasets identified candidate drugs including existing chemotherapies

Qing Wen; Paul O'Reilly; Philip D Dunne; Mark Lawler; Sandra Van Schaeybroeck; Manuel Salto-Tellez; Peter Hamilton; Shu-Dong Zhang

doi:10.1186/1752-0509-9-S5-S4

Connectivity mapping using a combined gene signature from multiple colorectal cancer datasets identified candidate drugs including existing chemotherapies

Qing Wen
, Paul O'Reilly
, Philip D Dunne
, Mark Lawler
, Sandra Van Schaeybroeck
, Manuel Salto-Tellez
, Peter Hamilton
, Shu-Dong Zhang

Research output: Contribution to journal › Article › peer-review

17 Citations (Scopus)

75 Downloads (Pure)

Original language	English
Pages (from-to)	S4
Journal	BMC Systems Biology
Volume	9
Issue number	Suppl
DOIs	https://doi.org/10.1186/1752-0509-9-S5-S4
Publication status	Published (in print/issue) - 2015

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

connectivity mapping
gene signature
systems approach
multiple datasets
colorectal cancer
irinotecan
etoposide

Access to Document

10.1186/1752-0509-9-S5-S4

2015-BMC-Sys-1752-0509-9-S5-S4Final published version, 567 KB

Cite this

@article{0491259045604e25aaf899e2e446fb46,

title = "Connectivity mapping using a combined gene signature from multiple colorectal cancer datasets identified candidate drugs including existing chemotherapies",

keywords = "connectivity mapping, gene signature, systems approach, multiple datasets, colorectal cancer, irinotecan, etoposide",

author = "Qing Wen and Paul O'Reilly and Dunne, \{Philip D\} and Mark Lawler and \{Van Schaeybroeck\}, Sandra and Manuel Salto-Tellez and Peter Hamilton and Shu-Dong Zhang",

year = "2015",

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language = "English",

volume = "9",

pages = "S4",

journal = "BMC Systems Biology",

issn = "1752-0509",

publisher = "BioMed Central Ltd.",

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TY - JOUR

T1 - Connectivity mapping using a combined gene signature from multiple colorectal cancer datasets identified candidate drugs including existing chemotherapies

AU - Wen, Qing

AU - O'Reilly, Paul

AU - Dunne, Philip D

AU - Lawler, Mark

AU - Van Schaeybroeck, Sandra

AU - Salto-Tellez, Manuel

AU - Hamilton, Peter

AU - Zhang, Shu-Dong

PY - 2015

Y1 - 2015

KW - connectivity mapping

KW - gene signature

KW - systems approach

KW - multiple datasets

KW - colorectal cancer

KW - irinotecan

KW - etoposide

U2 - 10.1186/1752-0509-9-S5-S4

DO - 10.1186/1752-0509-9-S5-S4

M3 - Article

SN - 1752-0509

VL - 9

SP - S4

JO - BMC Systems Biology

JF - BMC Systems Biology

IS - Suppl

ER -