Connectivity mapping (ssCMap) to predict A20-inducing drugs and their antiinflammatory action in cystic fibrosis

Beth Malcomson, Hollie Wilson, Eleonora Veglia, Gayathri Thillaiyampalam, Ruth Barsden, Shauna Donegan, Amal El Banna, Joseph S. Elborn, Madeleine Ennis, Catriona Kelly, Shu-Dong Zhang, Bettina C. Schock

Research output: Contribution to journalArticle

18 Citations (Scopus)
LanguageEnglish
PagesE3725-E3734
JournalProceedings of the National Academy of Sciences
Volume113
Issue number26
Early online date10 Jun 2016
DOIs
Publication statusPublished - 28 Jun 2016

Keywords

  • A20
  • NF-κB
  • connectivity mapping
  • drug repositioning
  • CF airway inflammation

Cite this

Malcomson, B., Wilson, H., Veglia, E., Thillaiyampalam, G., Barsden, R., Donegan, S., ... Schock, B. C. (2016). Connectivity mapping (ssCMap) to predict A20-inducing drugs and their antiinflammatory action in cystic fibrosis. Proceedings of the National Academy of Sciences, 113(26), E3725-E3734. https://doi.org/10.1073/pnas.1520289113
Malcomson, Beth ; Wilson, Hollie ; Veglia, Eleonora ; Thillaiyampalam, Gayathri ; Barsden, Ruth ; Donegan, Shauna ; El Banna, Amal ; Elborn, Joseph S. ; Ennis, Madeleine ; Kelly, Catriona ; Zhang, Shu-Dong ; Schock, Bettina C. / Connectivity mapping (ssCMap) to predict A20-inducing drugs and their antiinflammatory action in cystic fibrosis. In: Proceedings of the National Academy of Sciences. 2016 ; Vol. 113, No. 26. pp. E3725-E3734.
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author = "Beth Malcomson and Hollie Wilson and Eleonora Veglia and Gayathri Thillaiyampalam and Ruth Barsden and Shauna Donegan and {El Banna}, Amal and Elborn, {Joseph S.} and Madeleine Ennis and Catriona Kelly and Shu-Dong Zhang and Schock, {Bettina C.}",
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Malcomson, B, Wilson, H, Veglia, E, Thillaiyampalam, G, Barsden, R, Donegan, S, El Banna, A, Elborn, JS, Ennis, M, Kelly, C, Zhang, S-D & Schock, BC 2016, 'Connectivity mapping (ssCMap) to predict A20-inducing drugs and their antiinflammatory action in cystic fibrosis', Proceedings of the National Academy of Sciences, vol. 113, no. 26, pp. E3725-E3734. https://doi.org/10.1073/pnas.1520289113

Connectivity mapping (ssCMap) to predict A20-inducing drugs and their antiinflammatory action in cystic fibrosis. / Malcomson, Beth; Wilson, Hollie; Veglia, Eleonora; Thillaiyampalam, Gayathri; Barsden, Ruth; Donegan, Shauna; El Banna, Amal; Elborn, Joseph S.; Ennis, Madeleine; Kelly, Catriona; Zhang, Shu-Dong; Schock, Bettina C.

In: Proceedings of the National Academy of Sciences, Vol. 113, No. 26, 28.06.2016, p. E3725-E3734.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Connectivity mapping (ssCMap) to predict A20-inducing drugs and their antiinflammatory action in cystic fibrosis

AU - Malcomson, Beth

AU - Wilson, Hollie

AU - Veglia, Eleonora

AU - Thillaiyampalam, Gayathri

AU - Barsden, Ruth

AU - Donegan, Shauna

AU - El Banna, Amal

AU - Elborn, Joseph S.

AU - Ennis, Madeleine

AU - Kelly, Catriona

AU - Zhang, Shu-Dong

AU - Schock, Bettina C.

PY - 2016/6/28

Y1 - 2016/6/28

KW - A20

KW - NF-κB

KW - connectivity mapping

KW - drug repositioning

KW - CF airway inflammation

U2 - 10.1073/pnas.1520289113

DO - 10.1073/pnas.1520289113

M3 - Article

VL - 113

SP - E3725-E3734

JO - Proceedings of the National Academy of Sciences

T2 - Proceedings of the National Academy of Sciences

JF - Proceedings of the National Academy of Sciences

SN - 0027-8424

IS - 26

ER -