Common transcription factors between Hepatitis B virus (HBV) and Interleukin-8 (IL-8)

    Research output: Non-textual formWeb publication/site

    Abstract

    The immune system is connected by many signalling proteins known as cytokines and chemokines. These proteins are encoded by genes of the immune system which can be activated by many stimuli such as viral infection. It is therefore conceivable that control of gene regulation in both host and virus, may employ common mechanisms. Here we look at Interleukin-8 (IL-8) and Hepatitis B virus (HBV). The transcription factors that bind to the selected promoters and enhancers were identified from an extensive literature base. The data provided by the literature regarding each promoter or enhancer was recorded in a database. This data was then assembled to produce a map for both a host gene promoter and a viral promoter or enhancer region using the Systems Biology Genomic Notation (SBGN). These maps define how theses factors interact and the position at which this interaction occurs within the region of interest.
    LanguageEnglish
    DOIs
    Publication statusPublished - 21 Aug 2013

    Fingerprint

    Hepatitis B virus
    interleukin-8
    transcription factors
    promoter regions
    immune system
    genes
    chemokines
    cytokines
    proteins
    genomics
    Biological Sciences
    viruses
    infection

    Keywords

    • sbgn
    • il8
    • hbv

    Cite this

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    title = "Common transcription factors between Hepatitis B virus (HBV) and Interleukin-8 (IL-8)",
    abstract = "The immune system is connected by many signalling proteins known as cytokines and chemokines. These proteins are encoded by genes of the immune system which can be activated by many stimuli such as viral infection. It is therefore conceivable that control of gene regulation in both host and virus, may employ common mechanisms. Here we look at Interleukin-8 (IL-8) and Hepatitis B virus (HBV). The transcription factors that bind to the selected promoters and enhancers were identified from an extensive literature base. The data provided by the literature regarding each promoter or enhancer was recorded in a database. This data was then assembled to produce a map for both a host gene promoter and a viral promoter or enhancer region using the Systems Biology Genomic Notation (SBGN). These maps define how theses factors interact and the position at which this interaction occurs within the region of interest.",
    keywords = "sbgn, il8, hbv",
    author = "Steven Watterson",
    year = "2013",
    month = "8",
    day = "21",
    doi = "10.6084/m9.figshare.776903",
    language = "English",

    }

    TY - ADVS

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    AU - Watterson, Steven

    PY - 2013/8/21

    Y1 - 2013/8/21

    N2 - The immune system is connected by many signalling proteins known as cytokines and chemokines. These proteins are encoded by genes of the immune system which can be activated by many stimuli such as viral infection. It is therefore conceivable that control of gene regulation in both host and virus, may employ common mechanisms. Here we look at Interleukin-8 (IL-8) and Hepatitis B virus (HBV). The transcription factors that bind to the selected promoters and enhancers were identified from an extensive literature base. The data provided by the literature regarding each promoter or enhancer was recorded in a database. This data was then assembled to produce a map for both a host gene promoter and a viral promoter or enhancer region using the Systems Biology Genomic Notation (SBGN). These maps define how theses factors interact and the position at which this interaction occurs within the region of interest.

    AB - The immune system is connected by many signalling proteins known as cytokines and chemokines. These proteins are encoded by genes of the immune system which can be activated by many stimuli such as viral infection. It is therefore conceivable that control of gene regulation in both host and virus, may employ common mechanisms. Here we look at Interleukin-8 (IL-8) and Hepatitis B virus (HBV). The transcription factors that bind to the selected promoters and enhancers were identified from an extensive literature base. The data provided by the literature regarding each promoter or enhancer was recorded in a database. This data was then assembled to produce a map for both a host gene promoter and a viral promoter or enhancer region using the Systems Biology Genomic Notation (SBGN). These maps define how theses factors interact and the position at which this interaction occurs within the region of interest.

    KW - sbgn

    KW - il8

    KW - hbv

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    DO - 10.6084/m9.figshare.776903

    M3 - Web publication/site

    ER -