Cognitive function in healthy older European adults: the ZENITH study

EEA Simpson; E Maylor; G Rae; N Meunier; M Andriollo-Sanchez; G Catasta; Christopher McConville; M Ferry; A Polito; B Stewart-Knox; D Secker; C Coudray

Cognitive function in healthy older European adults: the ZENITH study

EEA Simpson, E Maylor, G Rae, N Meunier, M Andriollo-Sanchez, G Catasta, Christopher McConville, M Ferry, A Polito, B Stewart-Knox, D Secker, C Coudray

Research output: Contribution to journal › Article › peer-review

21 Citations (Scopus)

Abstract

Objective: Baseline data are reported from a study of the effects of zinc supplementation on cognitive function in older adults as assessed by the CANTAB computerised test battery. Design: This is a multicentre prospective intervention study employing a randomised double-blind design. Setting: European community-based study. Participants: There are 387 healthy adults aged 55-87 y from centres in France, Italy and Northern Ireland. Interventions: Measures of visual memory, working memory and attention were obtained at baseline (prior to supplementation). Results: Younger adults (<70 y) performed significantly better than older adults (> 70 y) on all tests, with minimal differences between centres. In addition, men outperformed women on tests of spatial span, pattern recognition memory and reaction times, although these gender differences varied somewhat between centres. Conclusions: The results are generally consistent with previous age- and gender-related effects on cognitive functioning.

Original language	English
Pages (from-to)	S26-S30
Journal	European Journal of Clinical Nutrition
Volume	59
Publication status	Published (in print/issue) - 2005

Cite this

@article{cddf35b3ea8e42d89855083038b5c0bf,

title = "Cognitive function in healthy older European adults: the ZENITH study",

abstract = "Objective: Baseline data are reported from a study of the effects of zinc supplementation on cognitive function in older adults as assessed by the CANTAB computerised test battery. Design: This is a multicentre prospective intervention study employing a randomised double-blind design. Setting: European community-based study. Participants: There are 387 healthy adults aged 55-87 y from centres in France, Italy and Northern Ireland. Interventions: Measures of visual memory, working memory and attention were obtained at baseline (prior to supplementation). Results: Younger adults (<70 y) performed significantly better than older adults (> 70 y) on all tests, with minimal differences between centres. In addition, men outperformed women on tests of spatial span, pattern recognition memory and reaction times, although these gender differences varied somewhat between centres. Conclusions: The results are generally consistent with previous age- and gender-related effects on cognitive functioning.",

author = "EEA Simpson and E Maylor and G Rae and N Meunier and M Andriollo-Sanchez and G Catasta and Christopher McConville and M Ferry and A Polito and B Stewart-Knox and D Secker and C Coudray",

year = "2005",

language = "English",

volume = "59",

pages = "S26--S30",

journal = "European Journal of Clinical Nutrition",

issn = "0954-3007",

publisher = "Springer",

}

TY - JOUR

T1 - Cognitive function in healthy older European adults: the ZENITH study

AU - Simpson, EEA

AU - Maylor, E

AU - Rae, G

AU - Meunier, N

AU - Andriollo-Sanchez, M

AU - Catasta, G

AU - McConville, Christopher

AU - Ferry, M

AU - Polito, A

AU - Stewart-Knox, B

AU - Secker, D

AU - Coudray, C

PY - 2005

Y1 - 2005

N2 - Objective: Baseline data are reported from a study of the effects of zinc supplementation on cognitive function in older adults as assessed by the CANTAB computerised test battery. Design: This is a multicentre prospective intervention study employing a randomised double-blind design. Setting: European community-based study. Participants: There are 387 healthy adults aged 55-87 y from centres in France, Italy and Northern Ireland. Interventions: Measures of visual memory, working memory and attention were obtained at baseline (prior to supplementation). Results: Younger adults (<70 y) performed significantly better than older adults (> 70 y) on all tests, with minimal differences between centres. In addition, men outperformed women on tests of spatial span, pattern recognition memory and reaction times, although these gender differences varied somewhat between centres. Conclusions: The results are generally consistent with previous age- and gender-related effects on cognitive functioning.

AB - Objective: Baseline data are reported from a study of the effects of zinc supplementation on cognitive function in older adults as assessed by the CANTAB computerised test battery. Design: This is a multicentre prospective intervention study employing a randomised double-blind design. Setting: European community-based study. Participants: There are 387 healthy adults aged 55-87 y from centres in France, Italy and Northern Ireland. Interventions: Measures of visual memory, working memory and attention were obtained at baseline (prior to supplementation). Results: Younger adults (<70 y) performed significantly better than older adults (> 70 y) on all tests, with minimal differences between centres. In addition, men outperformed women on tests of spatial span, pattern recognition memory and reaction times, although these gender differences varied somewhat between centres. Conclusions: The results are generally consistent with previous age- and gender-related effects on cognitive functioning.

M3 - Article

SN - 0954-3007

VL - 59

SP - S26-S30

JO - European Journal of Clinical Nutrition

JF - European Journal of Clinical Nutrition

ER -

Cognitive function in healthy older European adults: the ZENITH study

Abstract

Fingerprint

Cite this