Coefficients for the Derivation of an ST Sensitive Patch Based Lead System from the 12 Lead Electrocardiogram

Michael Jennings, Ali Rababah, Daniel Gueldenring, James McLaughlin, D Finlay

Research output: Contribution to conferencePaperpeer-review

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There are limited datasets available to facilitate the evaluation of patch-based lead systems, so the leads must be derived from existing data, mainly the 12-lead ECG. We have previously introduced a short spaced lead (SSL) system consisting of two leads with the largest ST segment changes during ischaemic-type episodes. In this study, we aim to evaluate the derivation of this patch-based lead system from the 12-lead ECG.
Method: Thoracic body surface potential maps (BSPM) were recorded from n=734 patients. Using Laplacian interpolation, each recording was expanded to the 352-node Dalhousie torso. The eight independent channels of the 12-lead ECG were extracted (I, II, V1-V6) with the two leads of the SSL patch
Coefficients were derived using linear regression from the 12-lead ECG to the SSL patch.
Results: The median Pearson correlation coefficients (CC) and root mean square error (RMSE) for each lead were calculated as follows (CC/RMSE): 0.986/74.3 uV (ST monitoring lead); 0.976/65.3 uV (spatially orthogonal lead).
Conclusion: We have developed coefficients that allow the derivation of a patch-based lead system from the 12-lead ECG. Given the high correlation, it is possible to generate short spaced lead systems from existing diagnostic lead systems, however, amplitude errors are introduced in the process.
Original languageEnglish
Number of pages4
Publication statusAccepted/In press - 24 Jun 2021
EventComputing in Cardiology 2021 - Hotel Passage, Brno, Czech Republic
Duration: 12 Sept 202115 Sept 2021


ConferenceComputing in Cardiology 2021
Abbreviated titleCinC21
Country/TerritoryCzech Republic
Internet address


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