Chemical engineering of protein cages and nanoparticles for pharmaceutical applications

Alaa A.a. Aljabali; Mazhar S. Al Zoubi; Lorca Alzoubi; Khalid M. Al-batanyeh; Mohammad A. Obeid; Murtaza M. Tambuwala

doi:10.1016/B978-0-12-820702-4.00017-9

Chemical engineering of protein cages and nanoparticles for pharmaceutical applications

Alaa A.a. Aljabali
, Mazhar S. Al Zoubi
, Lorca Alzoubi
, Khalid M. Al-batanyeh
, Mohammad A. Obeid
, Murtaza M. Tambuwala

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

10 Citations (Scopus)

Abstract

Protein chemical modification is one of the essential tools in protein modifications. Many chemical methods have been developed to impart new functionalities to the protein surface through the reactivity and selectivity of amino acid side chains. Various chemical reactions are available for both biologists and chemists for the chemical and genetic engineering of proteins. This chapter explores the different chemical reactions that are accessible for selective protein modification and targeting methods of nanoparticles (NPs). In addition, it explores some of their main applications in pharmaceutical nanotechnology.

Original language	English
Title of host publication	Nanofabrication for Smart Nanosensor Applications
Publisher	Elsevier
Pages	415-433
ISBN (Print)	9780128207024
DOIs	https://doi.org/10.1016/B978-0-12-820702-4.00017-9
Publication status	Published (in print/issue) - 26 Jun 2020

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1016/B978-0-12-820702-4.00017-9

https://linkinghub.elsevier.com/retrieve/pii/B9780128207024000179

Cite this

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title = "Chemical engineering of protein cages and nanoparticles for pharmaceutical applications",

abstract = "Protein chemical modification is one of the essential tools in protein modifications. Many chemical methods have been developed to impart new functionalities to the protein surface through the reactivity and selectivity of amino acid side chains. Various chemical reactions are available for both biologists and chemists for the chemical and genetic engineering of proteins. This chapter explores the different chemical reactions that are accessible for selective protein modification and targeting methods of nanoparticles (NPs). In addition, it explores some of their main applications in pharmaceutical nanotechnology.",

author = "Aljabali, \{Alaa A.a.\} and \{Al Zoubi\}, \{Mazhar S.\} and Lorca Alzoubi and Al-batanyeh, \{Khalid M.\} and Obeid, \{Mohammad A.\} and Tambuwala, \{Murtaza M.\}",

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T1 - Chemical engineering of protein cages and nanoparticles for pharmaceutical applications

AU - Aljabali, Alaa A.a.

AU - Al Zoubi, Mazhar S.

AU - Alzoubi, Lorca

AU - Al-batanyeh, Khalid M.

AU - Obeid, Mohammad A.

AU - Tambuwala, Murtaza M.

PY - 2020/6/26

Y1 - 2020/6/26

N2 - Protein chemical modification is one of the essential tools in protein modifications. Many chemical methods have been developed to impart new functionalities to the protein surface through the reactivity and selectivity of amino acid side chains. Various chemical reactions are available for both biologists and chemists for the chemical and genetic engineering of proteins. This chapter explores the different chemical reactions that are accessible for selective protein modification and targeting methods of nanoparticles (NPs). In addition, it explores some of their main applications in pharmaceutical nanotechnology.

AB - Protein chemical modification is one of the essential tools in protein modifications. Many chemical methods have been developed to impart new functionalities to the protein surface through the reactivity and selectivity of amino acid side chains. Various chemical reactions are available for both biologists and chemists for the chemical and genetic engineering of proteins. This chapter explores the different chemical reactions that are accessible for selective protein modification and targeting methods of nanoparticles (NPs). In addition, it explores some of their main applications in pharmaceutical nanotechnology.

U2 - 10.1016/B978-0-12-820702-4.00017-9

DO - 10.1016/B978-0-12-820702-4.00017-9

M3 - Chapter

SN - 9780128207024

SP - 415

EP - 433

BT - Nanofabrication for Smart Nanosensor Applications

PB - Elsevier

ER -

Chemical engineering of protein cages and nanoparticles for pharmaceutical applications

Abstract

UN SDGs

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