Characterization of Lemongrass Extract (Cymbopagon citratus) Nanoemulsion and Its Application as an Antibiofilm Agent in Acrylic Resin

Vinna K. Sugiaman; Rosalina I. Saputri; Silvia Naliani; Jane A.V. Wibisono; Jeffrey; Wayan L. Demolsky; Wahyu Widowati; Agung Novianto

doi:10.4103/jpbs.jpbs_418_24

Characterization of Lemongrass Extract (Cymbopagon citratus) Nanoemulsion and Its Application as an Antibiofilm Agent in Acrylic Resin

Vinna K. Sugiaman, Rosalina I. Saputri, Silvia Naliani, Jane A.V. Wibisono, Jeffrey, Wayan L. Demolsky, Wahyu Widowati, Agung Novianto

School of Pharm. & Pharmaceut. Sc.

Research output: Contribution to journal › Article › peer-review

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Abstract

Background: An antimicrobial agent is needed for denture cleaning, such as lemongrass (LG), which has a bioactive antimicrobial component. Methods: This research analyzed LG extract nanoparticles with a particle size analyzer, ZPA, and biofilm formation inhibition on resin acrylic surfaces. Results: We found that there is high stability in nanoparticle size, while other concentrations, including chlorhexidine as a positive control, did not show any statistical differences. Conclusion: Lemongrass oil nanoemulsion has proved to be an antibiofilm and effective as a denture cleaning agent because of its ability to inhibit Streptococcus mutans and Candida albicans growth.

Original language	English
Pages (from-to)	S2715-S2717
Number of pages	3
Journal	Journal of Pharmacy And Bioallied Sciences
Volume	16
Issue number	3
Early online date	31 Jul 2024
DOIs	https://doi.org/10.4103/jpbs.jpbs_418_24
Publication status	Published online - 31 Jul 2024

Bibliographical note

Publisher Copyright:
© 2024 Journal of Pharmacy and Bioallied Sciences.

Funding

Funding support from Maranatha Christian University under Grant number 024/SK/ADD/UKM/VII/2022.

Keywords

Acrylic resin
antibiofilm
Candida albicans
Cymbopogon citratus
nanoemulsion
Streptococcus mutans

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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characterization_of_lemongrass_extract__cymbopagon.260Final published version, 879 KBLicence: CC BY-NC-SA

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Sugiaman, V. K., Saputri, R. I., Naliani, S., Wibisono, J. A. V., Jeffrey, Demolsky, W. L., Widowati, W., & Novianto, A. (2024). Characterization of Lemongrass Extract (Cymbopagon citratus) Nanoemulsion and Its Application as an Antibiofilm Agent in Acrylic Resin. Journal of Pharmacy And Bioallied Sciences, 16(3), S2715-S2717. Advance online publication. https://doi.org/10.4103/jpbs.jpbs_418_24

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abstract = "Background: An antimicrobial agent is needed for denture cleaning, such as lemongrass (LG), which has a bioactive antimicrobial component. Methods: This research analyzed LG extract nanoparticles with a particle size analyzer, ZPA, and biofilm formation inhibition on resin acrylic surfaces. Results: We found that there is high stability in nanoparticle size, while other concentrations, including chlorhexidine as a positive control, did not show any statistical differences. Conclusion: Lemongrass oil nanoemulsion has proved to be an antibiofilm and effective as a denture cleaning agent because of its ability to inhibit Streptococcus mutans and Candida albicans growth.",

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AU - Sugiaman, Vinna K.

AU - Saputri, Rosalina I.

AU - Naliani, Silvia

AU - Wibisono, Jane A.V.

AU - Jeffrey,

AU - Demolsky, Wayan L.

AU - Widowati, Wahyu

AU - Novianto, Agung

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AB - Background: An antimicrobial agent is needed for denture cleaning, such as lemongrass (LG), which has a bioactive antimicrobial component. Methods: This research analyzed LG extract nanoparticles with a particle size analyzer, ZPA, and biofilm formation inhibition on resin acrylic surfaces. Results: We found that there is high stability in nanoparticle size, while other concentrations, including chlorhexidine as a positive control, did not show any statistical differences. Conclusion: Lemongrass oil nanoemulsion has proved to be an antibiofilm and effective as a denture cleaning agent because of its ability to inhibit Streptococcus mutans and Candida albicans growth.

KW - Acrylic resin

KW - antibiofilm

KW - Candida albicans

KW - Cymbopogon citratus

KW - nanoemulsion

KW - Streptococcus mutans

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ER -

Characterization of Lemongrass Extract (Cymbopagon citratus) Nanoemulsion and Its Application as an Antibiofilm Agent in Acrylic Resin

Abstract

Bibliographical note

Funding

Keywords

UN SDGs

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