Characterization of Lemongrass Extract (Cymbopagon citratus) Nanoemulsion and Its Application as an Antibiofilm Agent in Acrylic Resin

Vinna K. Sugiaman, Rosalina I. Saputri, Silvia Naliani, Jane A.V. Wibisono, Jeffrey, Wayan L. Demolsky, Wahyu Widowati, Agung Novianto

Research output: Contribution to journalArticlepeer-review

Abstract

Background: An antimicrobial agent is needed for denture cleaning, such as lemongrass (LG), which has a bioactive antimicrobial component. Methods: This research analyzed LG extract nanoparticles with a particle size analyzer, ZPA, and biofilm formation inhibition on resin acrylic surfaces. Results: We found that there is high stability in nanoparticle size, while other concentrations, including chlorhexidine as a positive control, did not show any statistical differences. Conclusion: Lemongrass oil nanoemulsion has proved to be an antibiofilm and effective as a denture cleaning agent because of its ability to inhibit Streptococcus mutans and Candida albicans growth.

Original languageEnglish
Pages (from-to)S2715-S2717
Number of pages3
JournalJournal of Pharmacy And Bioallied Sciences
Volume16
Issue number3
Early online date31 Jul 2024
DOIs
Publication statusPublished online - 31 Jul 2024

Bibliographical note

Publisher Copyright:
© 2024 Journal of Pharmacy and Bioallied Sciences.

Keywords

  • Acrylic resin
  • antibiofilm
  • Candida albicans
  • Cymbopogon citratus
  • nanoemulsion
  • Streptococcus mutans

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