Characterization of Flavonoids and Naphthopyranones in Methanol Extracts of Paepalanthus chiquitensis Herzog by HPLC-ESI-IT-MSn and Their Mutagenic Activity

FABIANA V. Zanutto; Paula Karina Boldrin; Eliana Aparecida Varanda; Samara Fernandes de Souza; Paulo Takeo Sano; Wagner Vilegas; Lourdes Campaner dos Santos

doi:10.3390/molecules18010244

Characterization of Flavonoids and Naphthopyranones in Methanol Extracts of Paepalanthus chiquitensis Herzog by HPLC-ESI-IT-MSn and Their Mutagenic Activity

FABIANA V. Zanutto
, Paula Karina Boldrin
, Eliana Aparecida Varanda
, Samara Fernandes de Souza
, Paulo Takeo Sano
, Wagner Vilegas
, Lourdes Campaner dos Santos

Research output: Contribution to journal › Article › peer-review

21 Citations (Scopus)

10 Downloads (Pure)

Abstract

A HPLC-ESI-IT-MSn method, based on high-performance liquid chromatography coupled to electrospray negative ionization multistage ion trap mass spectrometry, was developed for rapid identification of 24 flavonoid and naphthopyranone compounds. The methanol extracts of the capitulae and scapes of P. chiquitensis exhibited mutagenic activity in the Salmonella/microsome assay, against strain TA97a.

Original language	English
Pages (from-to)	244-262
Number of pages	19
Journal	Molecules
Volume	18
Early online date	27 Dec 2012
DOIs	https://doi.org/10.3390/molecules18010244
Publication status	Published online - 27 Dec 2012

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Paepalanthus
naphthopyranones
flavonoids
mutagenicity

Access to Document

10.3390/molecules18010244

molecules-18-00244Final published version, 427 KBLicence: Other

Cite this

Zanutto, FABIANA. V., Boldrin, P. K., Varanda, E. A., Fernandes de Souza, S., Takeo Sano, P., Vilegas, W., & Campaner dos Santos, L. (2012). Characterization of Flavonoids and Naphthopyranones in Methanol Extracts of Paepalanthus chiquitensis Herzog by HPLC-ESI-IT-MSn and Their Mutagenic Activity. Molecules, 18, 244-262. Advance online publication. https://doi.org/10.3390/molecules18010244

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abstract = "A HPLC-ESI-IT-MSn method, based on high-performance liquid chromatography coupled to electrospray negative ionization multistage ion trap mass spectrometry, was developed for rapid identification of 24 flavonoid and naphthopyranone compounds. The methanol extracts of the capitulae and scapes of P. chiquitensis exhibited mutagenic activity in the Salmonella/microsome assay, against strain TA97a.",

keywords = "Paepalanthus, naphthopyranones, flavonoids, mutagenicity",

author = "Zanutto, \{FABIANA V.\} and Boldrin, \{Paula Karina\} and Varanda, \{Eliana Aparecida\} and \{Fernandes de Souza\}, Samara and \{Takeo Sano\}, Paulo and Wagner Vilegas and \{Campaner dos Santos\}, Lourdes",

year = "2012",

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day = "27",

doi = "10.3390/molecules18010244",

language = "English",

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T1 - Characterization of Flavonoids and Naphthopyranones in Methanol Extracts of Paepalanthus chiquitensis Herzog by HPLC-ESI-IT-MSn and Their Mutagenic Activity

AU - Zanutto, FABIANA V.

AU - Boldrin, Paula Karina

AU - Varanda, Eliana Aparecida

AU - Fernandes de Souza, Samara

AU - Takeo Sano, Paulo

AU - Vilegas, Wagner

AU - Campaner dos Santos, Lourdes

PY - 2012/12/27

Y1 - 2012/12/27

N2 - A HPLC-ESI-IT-MSn method, based on high-performance liquid chromatography coupled to electrospray negative ionization multistage ion trap mass spectrometry, was developed for rapid identification of 24 flavonoid and naphthopyranone compounds. The methanol extracts of the capitulae and scapes of P. chiquitensis exhibited mutagenic activity in the Salmonella/microsome assay, against strain TA97a.

AB - A HPLC-ESI-IT-MSn method, based on high-performance liquid chromatography coupled to electrospray negative ionization multistage ion trap mass spectrometry, was developed for rapid identification of 24 flavonoid and naphthopyranone compounds. The methanol extracts of the capitulae and scapes of P. chiquitensis exhibited mutagenic activity in the Salmonella/microsome assay, against strain TA97a.

KW - Paepalanthus

KW - naphthopyranones

KW - flavonoids

KW - mutagenicity

UR - https://pubmed.ncbi.nlm.nih.gov/23271464/

U2 - 10.3390/molecules18010244

DO - 10.3390/molecules18010244

M3 - Article

SN - 1420-3049

VL - 18

SP - 244

EP - 262

JO - Molecules

JF - Molecules

ER -

Characterization of Flavonoids and Naphthopyranones in Methanol Extracts of Paepalanthus chiquitensis Herzog by HPLC-ESI-IT-MSn and Their Mutagenic Activity

Abstract

UN SDGs

Keywords

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