TY - JOUR
T1 - Characterization of Flavonoids and Naphthopyranones in Methanol Extracts of Paepalanthus chiquitensis Herzog by HPLC-ESI-IT-MSn and Their Mutagenic Activity
AU - Zanutto, FABIANA V.
AU - Boldrin, Paula Karina
AU - Varanda, Eliana Aparecida
AU - Fernandes de Souza, Samara
AU - Takeo Sano, Paulo
AU - Vilegas, Wagner
AU - Campaner dos Santos, Lourdes
PY - 2012/12/27
Y1 - 2012/12/27
N2 - A HPLC-ESI-IT-MSn method, based on high-performance liquid chromatography coupled to electrospray negative ionization multistage ion trap mass spectrometry, was developed for rapid identification of 24 flavonoid and naphthopyranone compounds. The methanol extracts of the capitulae and scapes of P. chiquitensis exhibited mutagenic activity in the Salmonella/microsome assay, against strain TA97a.
AB - A HPLC-ESI-IT-MSn method, based on high-performance liquid chromatography coupled to electrospray negative ionization multistage ion trap mass spectrometry, was developed for rapid identification of 24 flavonoid and naphthopyranone compounds. The methanol extracts of the capitulae and scapes of P. chiquitensis exhibited mutagenic activity in the Salmonella/microsome assay, against strain TA97a.
KW - Paepalanthus
KW - naphthopyranones
KW - flavonoids
KW - mutagenicity
UR - https://pubmed.ncbi.nlm.nih.gov/23271464/
U2 - 10.3390/molecules18010244
DO - 10.3390/molecules18010244
M3 - Article
SN - 1420-3049
VL - 18
SP - 244
EP - 262
JO - Molecules
JF - Molecules
ER -
