Carbon fibre composites: Integrated electrochemical sensors for wound management

D Sharp, S Forsythe, J Davis

Research output: Contribution to journalArticlepeer-review

20 Citations (Scopus)

Abstract

The applicability of employing a carbon fibre mesh as an electrochemical sensing substructure for assessing urate transformations within wound exudates is evaluated. Prototype sensor assemblies have been designed and their response characteristics towards uric acid and other common physiological components are detailed. Modification of the carbon fibre sensor through surface anodization and the application of cellulose acetate permselective barriers have been shown to lead to optimized responses and much greater sensitivity (1440% increase) and specificity. These could enable the accurate periodic monitoring of uric acid in wound fluid. The performance characteristics of the composite sensors in whole blood, serum and blister fluid have been investigated.
Original languageEnglish
Pages (from-to)87-93
JournalJournal of Biochemistry
Volume144
Issue number1
DOIs
Publication statusPublished (in print/issue) - Jul 2008

Keywords

  • carbon fibre
  • smart bandage
  • urate
  • uric acid
  • wound infection

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