Carbon fibre composites: Integrated electrochemical sensors for wound management

D Sharp, S Forsythe, J Davis

    Research output: Contribution to journalArticle

    10 Citations (Scopus)

    Abstract

    The applicability of employing a carbon fibre mesh as an electrochemical sensing substructure for assessing urate transformations within wound exudates is evaluated. Prototype sensor assemblies have been designed and their response characteristics towards uric acid and other common physiological components are detailed. Modification of the carbon fibre sensor through surface anodization and the application of cellulose acetate permselective barriers have been shown to lead to optimized responses and much greater sensitivity (1440% increase) and specificity. These could enable the accurate periodic monitoring of uric acid in wound fluid. The performance characteristics of the composite sensors in whole blood, serum and blister fluid have been investigated.
    LanguageEnglish
    Pages87-93
    JournalJournal of Biochemistry
    Volume144
    Issue number1
    DOIs
    Publication statusPublished - Jul 2008

    Fingerprint

    Electrochemical sensors
    Uric Acid
    Sensors
    Wounds and Injuries
    Composite materials
    Fluids
    Exudates and Transudates
    Blister
    Blood
    Monitoring
    Serum
    carbon fiber

    Keywords

    • carbon fibre
    • smart bandage
    • urate
    • uric acid
    • wound infection

    Cite this

    @article{e343083e0547422bbd57b5fe2c797a75,
    title = "Carbon fibre composites: Integrated electrochemical sensors for wound management",
    abstract = "The applicability of employing a carbon fibre mesh as an electrochemical sensing substructure for assessing urate transformations within wound exudates is evaluated. Prototype sensor assemblies have been designed and their response characteristics towards uric acid and other common physiological components are detailed. Modification of the carbon fibre sensor through surface anodization and the application of cellulose acetate permselective barriers have been shown to lead to optimized responses and much greater sensitivity (1440{\%} increase) and specificity. These could enable the accurate periodic monitoring of uric acid in wound fluid. The performance characteristics of the composite sensors in whole blood, serum and blister fluid have been investigated.",
    keywords = "carbon fibre, smart bandage, urate, uric acid, wound infection",
    author = "D Sharp and S Forsythe and J Davis",
    year = "2008",
    month = "7",
    doi = "10.1093/jb/mvn045",
    language = "English",
    volume = "144",
    pages = "87--93",
    journal = "Journal of Biochemistry",
    issn = "0021-924X",
    number = "1",

    }

    Carbon fibre composites: Integrated electrochemical sensors for wound management. / Sharp, D; Forsythe, S; Davis, J.

    In: Journal of Biochemistry, Vol. 144, No. 1, 07.2008, p. 87-93.

    Research output: Contribution to journalArticle

    TY - JOUR

    T1 - Carbon fibre composites: Integrated electrochemical sensors for wound management

    AU - Sharp, D

    AU - Forsythe, S

    AU - Davis, J

    PY - 2008/7

    Y1 - 2008/7

    N2 - The applicability of employing a carbon fibre mesh as an electrochemical sensing substructure for assessing urate transformations within wound exudates is evaluated. Prototype sensor assemblies have been designed and their response characteristics towards uric acid and other common physiological components are detailed. Modification of the carbon fibre sensor through surface anodization and the application of cellulose acetate permselective barriers have been shown to lead to optimized responses and much greater sensitivity (1440% increase) and specificity. These could enable the accurate periodic monitoring of uric acid in wound fluid. The performance characteristics of the composite sensors in whole blood, serum and blister fluid have been investigated.

    AB - The applicability of employing a carbon fibre mesh as an electrochemical sensing substructure for assessing urate transformations within wound exudates is evaluated. Prototype sensor assemblies have been designed and their response characteristics towards uric acid and other common physiological components are detailed. Modification of the carbon fibre sensor through surface anodization and the application of cellulose acetate permselective barriers have been shown to lead to optimized responses and much greater sensitivity (1440% increase) and specificity. These could enable the accurate periodic monitoring of uric acid in wound fluid. The performance characteristics of the composite sensors in whole blood, serum and blister fluid have been investigated.

    KW - carbon fibre

    KW - smart bandage

    KW - urate

    KW - uric acid

    KW - wound infection

    U2 - 10.1093/jb/mvn045

    DO - 10.1093/jb/mvn045

    M3 - Article

    VL - 144

    SP - 87

    EP - 93

    JO - Journal of Biochemistry

    T2 - Journal of Biochemistry

    JF - Journal of Biochemistry

    SN - 0021-924X

    IS - 1

    ER -