Carbon fibre composites: Integrated electrochemical sensors for wound management

D Sharp; S Forsythe; J Davis

doi:10.1093/jb/mvn045

Carbon fibre composites: Integrated electrochemical sensors for wound management

D Sharp, S Forsythe, J Davis

Research output: Contribution to journal › Article › peer-review

10 Citations (Scopus)

Abstract

The applicability of employing a carbon fibre mesh as an electrochemical sensing substructure for assessing urate transformations within wound exudates is evaluated. Prototype sensor assemblies have been designed and their response characteristics towards uric acid and other common physiological components are detailed. Modification of the carbon fibre sensor through surface anodization and the application of cellulose acetate permselective barriers have been shown to lead to optimized responses and much greater sensitivity (1440% increase) and specificity. These could enable the accurate periodic monitoring of uric acid in wound fluid. The performance characteristics of the composite sensors in whole blood, serum and blister fluid have been investigated.

Original language	English
Pages (from-to)	87-93
Journal	Journal of Biochemistry
Volume	144
Issue number	1
DOIs	https://doi.org/10.1093/jb/mvn045
Publication status	Published - Jul 2008

Keywords

carbon fibre
smart bandage
urate
uric acid
wound infection

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10.1093/jb/mvn045

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abstract = "The applicability of employing a carbon fibre mesh as an electrochemical sensing substructure for assessing urate transformations within wound exudates is evaluated. Prototype sensor assemblies have been designed and their response characteristics towards uric acid and other common physiological components are detailed. Modification of the carbon fibre sensor through surface anodization and the application of cellulose acetate permselective barriers have been shown to lead to optimized responses and much greater sensitivity (1440% increase) and specificity. These could enable the accurate periodic monitoring of uric acid in wound fluid. The performance characteristics of the composite sensors in whole blood, serum and blister fluid have been investigated.",

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AB - The applicability of employing a carbon fibre mesh as an electrochemical sensing substructure for assessing urate transformations within wound exudates is evaluated. Prototype sensor assemblies have been designed and their response characteristics towards uric acid and other common physiological components are detailed. Modification of the carbon fibre sensor through surface anodization and the application of cellulose acetate permselective barriers have been shown to lead to optimized responses and much greater sensitivity (1440% increase) and specificity. These could enable the accurate periodic monitoring of uric acid in wound fluid. The performance characteristics of the composite sensors in whole blood, serum and blister fluid have been investigated.

KW - carbon fibre

KW - smart bandage

KW - urate

KW - uric acid

KW - wound infection

U2 - 10.1093/jb/mvn045

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JO - Journal of Biochemistry

JF - Journal of Biochemistry

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