Bradykinins and their cDNA from piebald odorous frog, Odorrana schmackeri, skin

L Li, AJ Bjourson, JY He, GX Cai, PF Rao, C Shaw

Research output: Contribution to journalArticle

28 Citations (Scopus)

Abstract

Bradykinin, (des-Arg(9))-bradykinin and bradykinyl-VAPAS, were identified in the skin secretion of the piebald odorous frog, Odorrana schmackeri. Using 3'- and 5'-RACE reactions, bradykinin precursor cDNA was cloned and found to contain an open-reading frame of 311 amino acid residues. The preprobradykinin was found to consist of a putative signal peptide of approximately 20 amino acid residues, followed by seven tandem repeat coding domains of 43-44 amino acids. Bradykinin and its C-terminal extended molecular form were encoded on this single precursor and could be generated by differential post-translational processing. (C) 2003 Elsevier Inc. All rights reserved.
LanguageEnglish
Pages863-872
JournalPEPTIDES
Volume24
Issue number6
DOIs
Publication statusPublished - Jun 2003

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Bradykinin
Skin
Complementary DNA
Amino Acids
Tandem Repeat Sequences
Protein Sorting Signals
Processing

Cite this

Li, L ; Bjourson, AJ ; He, JY ; Cai, GX ; Rao, PF ; Shaw, C. / Bradykinins and their cDNA from piebald odorous frog, Odorrana schmackeri, skin. 2003 ; Vol. 24, No. 6. pp. 863-872.
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Bradykinins and their cDNA from piebald odorous frog, Odorrana schmackeri, skin. / Li, L; Bjourson, AJ; He, JY; Cai, GX; Rao, PF; Shaw, C.

Vol. 24, No. 6, 06.2003, p. 863-872.

Research output: Contribution to journalArticle

TY - JOUR

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AU - Li, L

AU - Bjourson, AJ

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AU - Rao, PF

AU - Shaw, C

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