Abstract
Bradykinin, (des-Arg(9))-bradykinin and bradykinyl-VAPAS, were identified in the skin secretion of the piebald odorous frog, Odorrana schmackeri. Using 3'- and 5'-RACE reactions, bradykinin precursor cDNA was cloned and found to contain an open-reading frame of 311 amino acid residues. The preprobradykinin was found to consist of a putative signal peptide of approximately 20 amino acid residues, followed by seven tandem repeat coding domains of 43-44 amino acids. Bradykinin and its C-terminal extended molecular form were encoded on this single precursor and could be generated by differential post-translational processing. (C) 2003 Elsevier Inc. All rights reserved.
| Original language | English |
|---|---|
| Pages (from-to) | 863-872 |
| Journal | Peptides |
| Volume | 24 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - Jun 2003 |
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Li, L., Bjourson, AJ., He, JY., Cai, GX., Rao, PF., & Shaw, C. (2003). Bradykinins and their cDNA from piebald odorous frog, Odorrana schmackeri, skin. Peptides, 24(6), 863-872. https://doi.org/10.1016/S0196-9781(03)00166-9