Abstract
Language | English |
---|---|
Pages | 863-872 |
Journal | Peptides |
Volume | 24 |
Issue number | 6 |
DOIs | |
Publication status | Published - Jun 2003 |
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Bradykinins and their cDNA from piebald odorous frog, Odorrana schmackeri, skin. / Li, L; Bjourson, AJ; He, JY; Cai, GX; Rao, PF; Shaw, C.
In: Peptides, Vol. 24, No. 6, 06.2003, p. 863-872.Research output: Contribution to journal › Article
TY - JOUR
T1 - Bradykinins and their cDNA from piebald odorous frog, Odorrana schmackeri, skin
AU - Li, L
AU - Bjourson, AJ
AU - He, JY
AU - Cai, GX
AU - Rao, PF
AU - Shaw, C
PY - 2003/6
Y1 - 2003/6
N2 - Bradykinin, (des-Arg(9))-bradykinin and bradykinyl-VAPAS, were identified in the skin secretion of the piebald odorous frog, Odorrana schmackeri. Using 3'- and 5'-RACE reactions, bradykinin precursor cDNA was cloned and found to contain an open-reading frame of 311 amino acid residues. The preprobradykinin was found to consist of a putative signal peptide of approximately 20 amino acid residues, followed by seven tandem repeat coding domains of 43-44 amino acids. Bradykinin and its C-terminal extended molecular form were encoded on this single precursor and could be generated by differential post-translational processing. (C) 2003 Elsevier Inc. All rights reserved.
AB - Bradykinin, (des-Arg(9))-bradykinin and bradykinyl-VAPAS, were identified in the skin secretion of the piebald odorous frog, Odorrana schmackeri. Using 3'- and 5'-RACE reactions, bradykinin precursor cDNA was cloned and found to contain an open-reading frame of 311 amino acid residues. The preprobradykinin was found to consist of a putative signal peptide of approximately 20 amino acid residues, followed by seven tandem repeat coding domains of 43-44 amino acids. Bradykinin and its C-terminal extended molecular form were encoded on this single precursor and could be generated by differential post-translational processing. (C) 2003 Elsevier Inc. All rights reserved.
U2 - 10.1016/S0196-9781(03)00166-9
DO - 10.1016/S0196-9781(03)00166-9
M3 - Article
VL - 24
SP - 863
EP - 872
JO - Peptides
T2 - Peptides
JF - Peptides
SN - 0196-9781
IS - 6
ER -