Bone Health in Coeliac Disease: Do B-vitamins have a role?

Michelle Clarke, Mary Ward, William Dickey, Helene McNulty

Research output: Other contribution

Abstract

Coeliac Disease (CD) is a common, autoimmune inflammatory condition induced by gluten consumption in genetically susceptible individuals. Patients with CD are at increased risk of osteoporosis, a feature often attributed to chronic calcium and/or vitamin D malabsorption. It is possible however that other nutritional factors also contribute to poor bone health in CD. As previously described in this journal by researchers at our centre, emerging evidence in generally healthy cohorts worldwide supports a potential role for certain B-vitamins in bone health. Here we consider the possibility that low B-vitamin status, and/ or elevated concentrations of the closely related metabolite homocysteine, may contribute to osteoporosis in CD.
LanguageEnglish
TypeReview article in Osteoporosis Review
Number of pages4
Publication statusPublished - 2013

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Vitamin B Complex
Celiac Disease
Bone and Bones
Health
Osteoporosis
Glutens
Homocysteine
Vitamin D
Research Personnel
Calcium

Cite this

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title = "Bone Health in Coeliac Disease: Do B-vitamins have a role?",
abstract = "Coeliac Disease (CD) is a common, autoimmune inflammatory condition induced by gluten consumption in genetically susceptible individuals. Patients with CD are at increased risk of osteoporosis, a feature often attributed to chronic calcium and/or vitamin D malabsorption. It is possible however that other nutritional factors also contribute to poor bone health in CD. As previously described in this journal by researchers at our centre, emerging evidence in generally healthy cohorts worldwide supports a potential role for certain B-vitamins in bone health. Here we consider the possibility that low B-vitamin status, and/ or elevated concentrations of the closely related metabolite homocysteine, may contribute to osteoporosis in CD.",
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Bone Health in Coeliac Disease: Do B-vitamins have a role? / Clarke, Michelle; Ward, Mary; Dickey, William; McNulty, Helene.

4 p. 2013, Review article in Osteoporosis Review.

Research output: Other contribution

TY - GEN

T1 - Bone Health in Coeliac Disease: Do B-vitamins have a role?

AU - Clarke, Michelle

AU - Ward, Mary

AU - Dickey, William

AU - McNulty, Helene

PY - 2013

Y1 - 2013

N2 - Coeliac Disease (CD) is a common, autoimmune inflammatory condition induced by gluten consumption in genetically susceptible individuals. Patients with CD are at increased risk of osteoporosis, a feature often attributed to chronic calcium and/or vitamin D malabsorption. It is possible however that other nutritional factors also contribute to poor bone health in CD. As previously described in this journal by researchers at our centre, emerging evidence in generally healthy cohorts worldwide supports a potential role for certain B-vitamins in bone health. Here we consider the possibility that low B-vitamin status, and/ or elevated concentrations of the closely related metabolite homocysteine, may contribute to osteoporosis in CD.

AB - Coeliac Disease (CD) is a common, autoimmune inflammatory condition induced by gluten consumption in genetically susceptible individuals. Patients with CD are at increased risk of osteoporosis, a feature often attributed to chronic calcium and/or vitamin D malabsorption. It is possible however that other nutritional factors also contribute to poor bone health in CD. As previously described in this journal by researchers at our centre, emerging evidence in generally healthy cohorts worldwide supports a potential role for certain B-vitamins in bone health. Here we consider the possibility that low B-vitamin status, and/ or elevated concentrations of the closely related metabolite homocysteine, may contribute to osteoporosis in CD.

M3 - Other contribution

ER -