Auditory cueing in Parkinson's patients with freezing of gait. What matters most: action-relevance or cue-continuity?

William R. Young, Lauren Shreve, Emma Jane Quinn, Cathy Craig, Helen Bronte-Stewart

Research output: Contribution to journalArticle

27 Citations (Scopus)

Abstract

Gait disturbances are a common feature of Parkinson's disease, one of the most severe being freezing of gait. Sensory cueing is a common method used to facilitate stepping in people with Parkinson's. Recent work has shown that, compared to walking to a metronome, Parkinson's patients without freezing of gait (nFOG) showed reduced gait variability when imitating recorded sounds of footsteps made on gravel. However, it is not known if these benefits are realised through the continuity of the acoustic information or the action-relevance. Furthermore, no study has examined if these benefits extend to PD with freezing of gait. We prepared four different auditory cues (varying in action-relevance and acoustic continuity) and asked 19 Parkinson's patients (10 nFOG, 9 with freezing of gait (FOG)) to step in place to each cue. Results showed a superiority of action-relevant cues (regardless of cue-continuity) for inducing reductions in Step coefficient of variation (CV). Acoustic continuity was associated with a significant reduction in Swing CV. Neither cue-continuity nor action-relevance was independently sufficient to increase the time spent stepping before freezing. However, combining both attributes in the same cue did yield significant improvements. This study demonstrates the potential of using action-sounds as sensory cues for Parkinson's patients with freezing of gait. We suggest that the improvements shown might be considered audio-motor ‘priming’ (i.e., listening to the sounds of footsteps will engage sensorimotor circuitry relevant to the production of that same action, thus effectively bypassing the defective basal ganglia).
LanguageEnglish
Pages54-62
Number of pages9
JournalNeuropsychologia
Volume87
Early online date6 May 2016
DOIs
Publication statusPublished - 1 Jul 2016

Fingerprint

Gait
Freezing
Cues
Acoustics
Basal Ganglia
Action Potentials
Walking
Parkinson Disease

Keywords

  • Parkinson's
  • Freezing of gait
  • Sensory cueing
  • Imitation
  • Auditory observation
  • Audio-motor priming

Cite this

Young, William R. ; Shreve, Lauren ; Quinn, Emma Jane ; Craig, Cathy ; Bronte-Stewart, Helen. / Auditory cueing in Parkinson's patients with freezing of gait. What matters most: action-relevance or cue-continuity?. In: Neuropsychologia. 2016 ; Vol. 87. pp. 54-62.
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Auditory cueing in Parkinson's patients with freezing of gait. What matters most: action-relevance or cue-continuity? / Young, William R.; Shreve, Lauren; Quinn, Emma Jane; Craig, Cathy; Bronte-Stewart, Helen.

In: Neuropsychologia, Vol. 87, 01.07.2016, p. 54-62.

Research output: Contribution to journalArticle

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