TY - JOUR
T1 - Atheroprotective effects of (poly) phenols: a focus on cell cholesterol metabolism
AU - Zanotti, Ilaria
AU - Dall'Asta, Margherita
AU - Mena, Pedro
AU - Mele, Laura
AU - Bruni, Renato
AU - Ray, Sumantra
AU - Del Rio, Daniele
PY - 2015/1/1
Y1 - 2015/1/1
N2 - Collated observations from several epidemiological studies have demonstrated that dietary intake of (poly)phenols from nuts, coffee, cocoa, grapes, and berries may protect against the development of atherosclerosis. Whereas this beneficial activity has previously been linked mainly to antioxidant or anti-inflammatory properties, recently emerging data suggest mechanisms by which (poly)phenolic substances can modulate cellular lipid metabolism, thereby mitigating atherosclerotic plaque formation. In this review, both experimental studies and clinical trials investigating the atheroprotective effects of the most relevant dietary (poly)phenols are critically discussed.
AB - Collated observations from several epidemiological studies have demonstrated that dietary intake of (poly)phenols from nuts, coffee, cocoa, grapes, and berries may protect against the development of atherosclerosis. Whereas this beneficial activity has previously been linked mainly to antioxidant or anti-inflammatory properties, recently emerging data suggest mechanisms by which (poly)phenolic substances can modulate cellular lipid metabolism, thereby mitigating atherosclerotic plaque formation. In this review, both experimental studies and clinical trials investigating the atheroprotective effects of the most relevant dietary (poly)phenols are critically discussed.
UR - https://pure.ulster.ac.uk/en/publications/atheroprotective-effects-of-poly-phenols-a-focus-on-cell-choleste
UR - https://www.scopus.com/pages/publications/84922976178
U2 - 10.1039/c4fo00670d
DO - 10.1039/c4fo00670d
M3 - Article
SN - 2042-6469
VL - 6
SP - 13
EP - 31
JO - Food and Function
JF - Food and Function
IS - 1
ER -
