Associations between whole-blood serotonin and subjective mood in healthy male volunteers

E Williams; B Stewart-Knox; A Helander; Christopher McConville; I Bradbury; I Rowland

doi:10.1016/j.biopsycho.2005.03.002

Associations between whole-blood serotonin and subjective mood in healthy male volunteers

E Williams
, B Stewart-Knox
, A Helander
, Christopher McConville
, I Bradbury
, I Rowland

Research output: Contribution to journal › Article › peer-review

37 Citations (Scopus)

Abstract

Little is known regarding the relationship between how mood is experienced and biochemical factors. This research has explored potential relationships between whole-blood serotonin (5-HT) and subjective mood, measured using the Positive and Negative Affect Schedule (PANAS), in healthy males (n = 23). Univariate linear regression analysis indicated that 5-HT levels were positively related to positive affect (P = 0.002) but not negative affect. Whole-blood 5-HT concentrations therefore appear to predict mood in healthy males. More research using larger samples and including females is needed to explore further associations between biomarkers and subjective measures of mood. (c) 2005 Elsevier B.V. All rights reserved.

Original language	English
Pages (from-to)	171-174
Journal	Biological Psychology
Volume	71
Issue number	2
DOIs	https://doi.org/10.1016/j.biopsycho.2005.03.002
Publication status	Published (in print/issue) - Feb 2006

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title = "Associations between whole-blood serotonin and subjective mood in healthy male volunteers",

abstract = "Little is known regarding the relationship between how mood is experienced and biochemical factors. This research has explored potential relationships between whole-blood serotonin (5-HT) and subjective mood, measured using the Positive and Negative Affect Schedule (PANAS), in healthy males (n = 23). Univariate linear regression analysis indicated that 5-HT levels were positively related to positive affect (P = 0.002) but not negative affect. Whole-blood 5-HT concentrations therefore appear to predict mood in healthy males. More research using larger samples and including females is needed to explore further associations between biomarkers and subjective measures of mood. (c) 2005 Elsevier B.V. All rights reserved.",

author = "E Williams and B Stewart-Knox and A Helander and Christopher McConville and I Bradbury and I Rowland",

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AU - Williams, E

AU - Stewart-Knox, B

AU - Helander, A

AU - McConville, Christopher

AU - Bradbury, I

AU - Rowland, I

PY - 2006/2

Y1 - 2006/2

N2 - Little is known regarding the relationship between how mood is experienced and biochemical factors. This research has explored potential relationships between whole-blood serotonin (5-HT) and subjective mood, measured using the Positive and Negative Affect Schedule (PANAS), in healthy males (n = 23). Univariate linear regression analysis indicated that 5-HT levels were positively related to positive affect (P = 0.002) but not negative affect. Whole-blood 5-HT concentrations therefore appear to predict mood in healthy males. More research using larger samples and including females is needed to explore further associations between biomarkers and subjective measures of mood. (c) 2005 Elsevier B.V. All rights reserved.

AB - Little is known regarding the relationship between how mood is experienced and biochemical factors. This research has explored potential relationships between whole-blood serotonin (5-HT) and subjective mood, measured using the Positive and Negative Affect Schedule (PANAS), in healthy males (n = 23). Univariate linear regression analysis indicated that 5-HT levels were positively related to positive affect (P = 0.002) but not negative affect. Whole-blood 5-HT concentrations therefore appear to predict mood in healthy males. More research using larger samples and including females is needed to explore further associations between biomarkers and subjective measures of mood. (c) 2005 Elsevier B.V. All rights reserved.

U2 - 10.1016/j.biopsycho.2005.03.002

DO - 10.1016/j.biopsycho.2005.03.002

M3 - Article

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SP - 171

EP - 174

JO - Biological Psychology

JF - Biological Psychology

IS - 2

ER -

Associations between whole-blood serotonin and subjective mood in healthy male volunteers

Abstract

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