Associations between whole-blood serotonin and subjective mood in healthy male volunteers

E Williams, B Stewart-Knox, A Helander, Christopher McConville, I Bradbury, I Rowland

Research output: Contribution to journalArticle

21 Citations (Scopus)

Abstract

Little is known regarding the relationship between how mood is experienced and biochemical factors. This research has explored potential relationships between whole-blood serotonin (5-HT) and subjective mood, measured using the Positive and Negative Affect Schedule (PANAS), in healthy males (n = 23). Univariate linear regression analysis indicated that 5-HT levels were positively related to positive affect (P = 0.002) but not negative affect. Whole-blood 5-HT concentrations therefore appear to predict mood in healthy males. More research using larger samples and including females is needed to explore further associations between biomarkers and subjective measures of mood. (c) 2005 Elsevier B.V. All rights reserved.
LanguageEnglish
Pages171-174
JournalBiological Psychology
Volume71
Issue number2
DOIs
Publication statusPublished - Feb 2006

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Serotonin
Healthy Volunteers
Research
Linear Models
Appointments and Schedules
Biomarkers
Regression Analysis

Cite this

Williams, E ; Stewart-Knox, B ; Helander, A ; McConville, Christopher ; Bradbury, I ; Rowland, I. / Associations between whole-blood serotonin and subjective mood in healthy male volunteers. In: Biological Psychology. 2006 ; Vol. 71, No. 2. pp. 171-174.
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Associations between whole-blood serotonin and subjective mood in healthy male volunteers. / Williams, E; Stewart-Knox, B; Helander, A; McConville, Christopher; Bradbury, I; Rowland, I.

In: Biological Psychology, Vol. 71, No. 2, 02.2006, p. 171-174.

Research output: Contribution to journalArticle

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