Associations between DSM-IV mental disorders and subsequent self-reported diagnosis of cancer

Siobhan O'Neill, Jose Posada-Villa, Maria-Elena Medina-Mora, Ali Obaid Al-Hamzawi, Marina Piazza, Histaeru Tachimori, Chiyi Hu, Carmen Lim, Ronny Briffaerts, Jean-Pierre Lepine, Herbert Matschinger, Giovanni di-Gioralamo, Peter de Jonge, Jordi Alonso, Jose Migueal Caldas de Almedia, Silvia Florescu, Andrzej Kiejna, Daphna Levinson, Ron Kessler, Kate Scott

Research output: Contribution to journalArticle

19 Citations (Scopus)

Abstract

Objective
The associations between mental disorders and cancer remain unclear. It is also unknown whether any associations vary according to life stage or gender. This paper examines these research questions using data from the World Mental Health Survey Initiative.

Methods
The World Health Organization Composite International Diagnostic Interview retrospectively assessed the lifetime prevalence of 16 DSM-IV mental disorders in face-to-face household population surveys in nineteen countries (n = 52,095). Cancer was indicated by self-report of diagnosis. Smoking was assessed in questions about current and past tobacco use. Survival analyses estimated associations between first onset of mental disorders and subsequently reported cancer.

Results
After adjustment for comorbidity, panic disorder, specific phobia and alcohol abuse were associated with a subsequently self-reported diagnosis of cancer. There was an association between number of mental disorders and the likelihood of reporting a cancer diagnosis following the onset of the mental disorder.

This suggests that the associations between mental disorders and cancer risk may be generalised, rather than specific to a particular disorder. Depression is more strongly associated with self-reported cancers diagnosed early in life and in women. PTSD is also associated with cancers diagnosed early in life.

Conclusion
This study reports the magnitude of the associations between mental disorders and a self-reported diagnosis of cancer and provides information about the relevance of comorbidity, gender and the impact at different stages of life. The findings point to a link between the two conditions and lend support to arguments for early identification and treatment of mental disorders.
LanguageEnglish
Pages207-212
JournalJournal of Psychosomatic Research
Volume76
Issue number3
Early online date9 Jan 2014
DOIs
Publication statusPublished - 31 Mar 2014

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Mental Disorders
Diagnostic and Statistical Manual of Mental Disorders
Neoplasms
Comorbidity
Panic Disorder
Tobacco Use
Survival Analysis
Post-Traumatic Stress Disorders
Health Surveys
Self Report
Alcoholism
Mental Health
Smoking
Interviews
Depression
Research
Population

Keywords

  • cancer
  • psychiatry
  • mental disorder
  • epidemiology

Cite this

O'Neill, S., Posada-Villa, J., Medina-Mora, M-E., Al-Hamzawi, A. O., Piazza, M., Tachimori, H., ... Scott, K. (2014). Associations between DSM-IV mental disorders and subsequent self-reported diagnosis of cancer. Journal of Psychosomatic Research, 76(3), 207-212. https://doi.org/10.1016/j.jpsychores.2013.12.012
O'Neill, Siobhan ; Posada-Villa, Jose ; Medina-Mora, Maria-Elena ; Al-Hamzawi, Ali Obaid ; Piazza, Marina ; Tachimori, Histaeru ; Hu, Chiyi ; Lim, Carmen ; Briffaerts, Ronny ; Lepine, Jean-Pierre ; Matschinger, Herbert ; di-Gioralamo, Giovanni ; de Jonge, Peter ; Alonso, Jordi ; Caldas de Almedia, Jose Migueal ; Florescu, Silvia ; Kiejna, Andrzej ; Levinson, Daphna ; Kessler, Ron ; Scott, Kate. / Associations between DSM-IV mental disorders and subsequent self-reported diagnosis of cancer. In: Journal of Psychosomatic Research. 2014 ; Vol. 76, No. 3. pp. 207-212.
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abstract = "ObjectiveThe associations between mental disorders and cancer remain unclear. It is also unknown whether any associations vary according to life stage or gender. This paper examines these research questions using data from the World Mental Health Survey Initiative.MethodsThe World Health Organization Composite International Diagnostic Interview retrospectively assessed the lifetime prevalence of 16 DSM-IV mental disorders in face-to-face household population surveys in nineteen countries (n = 52,095). Cancer was indicated by self-report of diagnosis. Smoking was assessed in questions about current and past tobacco use. Survival analyses estimated associations between first onset of mental disorders and subsequently reported cancer.ResultsAfter adjustment for comorbidity, panic disorder, specific phobia and alcohol abuse were associated with a subsequently self-reported diagnosis of cancer. There was an association between number of mental disorders and the likelihood of reporting a cancer diagnosis following the onset of the mental disorder.This suggests that the associations between mental disorders and cancer risk may be generalised, rather than specific to a particular disorder. Depression is more strongly associated with self-reported cancers diagnosed early in life and in women. PTSD is also associated with cancers diagnosed early in life.ConclusionThis study reports the magnitude of the associations between mental disorders and a self-reported diagnosis of cancer and provides information about the relevance of comorbidity, gender and the impact at different stages of life. The findings point to a link between the two conditions and lend support to arguments for early identification and treatment of mental disorders.",
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author = "Siobhan O'Neill and Jose Posada-Villa and Maria-Elena Medina-Mora and Al-Hamzawi, {Ali Obaid} and Marina Piazza and Histaeru Tachimori and Chiyi Hu and Carmen Lim and Ronny Briffaerts and Jean-Pierre Lepine and Herbert Matschinger and Giovanni di-Gioralamo and {de Jonge}, Peter and Jordi Alonso and {Caldas de Almedia}, {Jose Migueal} and Silvia Florescu and Andrzej Kiejna and Daphna Levinson and Ron Kessler and Kate Scott",
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O'Neill, S, Posada-Villa, J, Medina-Mora, M-E, Al-Hamzawi, AO, Piazza, M, Tachimori, H, Hu, C, Lim, C, Briffaerts, R, Lepine, J-P, Matschinger, H, di-Gioralamo, G, de Jonge, P, Alonso, J, Caldas de Almedia, JM, Florescu, S, Kiejna, A, Levinson, D, Kessler, R & Scott, K 2014, 'Associations between DSM-IV mental disorders and subsequent self-reported diagnosis of cancer', Journal of Psychosomatic Research, vol. 76, no. 3, pp. 207-212. https://doi.org/10.1016/j.jpsychores.2013.12.012

Associations between DSM-IV mental disorders and subsequent self-reported diagnosis of cancer. / O'Neill, Siobhan; Posada-Villa, Jose; Medina-Mora, Maria-Elena; Al-Hamzawi, Ali Obaid; Piazza, Marina; Tachimori, Histaeru; Hu, Chiyi; Lim, Carmen; Briffaerts, Ronny; Lepine, Jean-Pierre; Matschinger, Herbert; di-Gioralamo, Giovanni; de Jonge, Peter; Alonso, Jordi; Caldas de Almedia, Jose Migueal; Florescu, Silvia; Kiejna, Andrzej; Levinson, Daphna; Kessler, Ron; Scott, Kate.

In: Journal of Psychosomatic Research, Vol. 76, No. 3, 31.03.2014, p. 207-212.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Associations between DSM-IV mental disorders and subsequent self-reported diagnosis of cancer

AU - O'Neill, Siobhan

AU - Posada-Villa, Jose

AU - Medina-Mora, Maria-Elena

AU - Al-Hamzawi, Ali Obaid

AU - Piazza, Marina

AU - Tachimori, Histaeru

AU - Hu, Chiyi

AU - Lim, Carmen

AU - Briffaerts, Ronny

AU - Lepine, Jean-Pierre

AU - Matschinger, Herbert

AU - di-Gioralamo, Giovanni

AU - de Jonge, Peter

AU - Alonso, Jordi

AU - Caldas de Almedia, Jose Migueal

AU - Florescu, Silvia

AU - Kiejna, Andrzej

AU - Levinson, Daphna

AU - Kessler, Ron

AU - Scott, Kate

PY - 2014/3/31

Y1 - 2014/3/31

N2 - ObjectiveThe associations between mental disorders and cancer remain unclear. It is also unknown whether any associations vary according to life stage or gender. This paper examines these research questions using data from the World Mental Health Survey Initiative.MethodsThe World Health Organization Composite International Diagnostic Interview retrospectively assessed the lifetime prevalence of 16 DSM-IV mental disorders in face-to-face household population surveys in nineteen countries (n = 52,095). Cancer was indicated by self-report of diagnosis. Smoking was assessed in questions about current and past tobacco use. Survival analyses estimated associations between first onset of mental disorders and subsequently reported cancer.ResultsAfter adjustment for comorbidity, panic disorder, specific phobia and alcohol abuse were associated with a subsequently self-reported diagnosis of cancer. There was an association between number of mental disorders and the likelihood of reporting a cancer diagnosis following the onset of the mental disorder.This suggests that the associations between mental disorders and cancer risk may be generalised, rather than specific to a particular disorder. Depression is more strongly associated with self-reported cancers diagnosed early in life and in women. PTSD is also associated with cancers diagnosed early in life.ConclusionThis study reports the magnitude of the associations between mental disorders and a self-reported diagnosis of cancer and provides information about the relevance of comorbidity, gender and the impact at different stages of life. The findings point to a link between the two conditions and lend support to arguments for early identification and treatment of mental disorders.

AB - ObjectiveThe associations between mental disorders and cancer remain unclear. It is also unknown whether any associations vary according to life stage or gender. This paper examines these research questions using data from the World Mental Health Survey Initiative.MethodsThe World Health Organization Composite International Diagnostic Interview retrospectively assessed the lifetime prevalence of 16 DSM-IV mental disorders in face-to-face household population surveys in nineteen countries (n = 52,095). Cancer was indicated by self-report of diagnosis. Smoking was assessed in questions about current and past tobacco use. Survival analyses estimated associations between first onset of mental disorders and subsequently reported cancer.ResultsAfter adjustment for comorbidity, panic disorder, specific phobia and alcohol abuse were associated with a subsequently self-reported diagnosis of cancer. There was an association between number of mental disorders and the likelihood of reporting a cancer diagnosis following the onset of the mental disorder.This suggests that the associations between mental disorders and cancer risk may be generalised, rather than specific to a particular disorder. Depression is more strongly associated with self-reported cancers diagnosed early in life and in women. PTSD is also associated with cancers diagnosed early in life.ConclusionThis study reports the magnitude of the associations between mental disorders and a self-reported diagnosis of cancer and provides information about the relevance of comorbidity, gender and the impact at different stages of life. The findings point to a link between the two conditions and lend support to arguments for early identification and treatment of mental disorders.

KW - cancer

KW - psychiatry

KW - mental disorder

KW - epidemiology

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JF - Journal of Psychosomatic Research

SN - 0022-3999

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