Aqueous Bark Extracts of Terminalia Arjuna Stimulates Insulin Release, Enhances Insulin Action and Inhibits Starch Digestion and Protein Glycation in Vitro

HAJ Thomson; Opeolu Ojo; Peter Flatt; YHA Abdel-Wahab

Aqueous Bark Extracts of Terminalia Arjuna Stimulates Insulin Release, Enhances Insulin Action and Inhibits Starch Digestion and Protein Glycation in Vitro

HAJ Thomson, Opeolu Ojo, Peter Flatt, YHA Abdel-Wahab

Research output: Contribution to journal › Article › peer-review

Abstract

Scientific evidence for the effects of Terminalia arjuna on diabetes mellitus is lacking. This study investigated the anti-diabetic efficacy and mode of action of the bark extract of Terminalia arjuna. Insulin-release from BRIN-BD11 cells was assessed in the absence or presence of T. arjuna extracts and modulators of insulin-secretion. Insulin concentration and intracellular calcium ([Ca2+]i) were measured by radioimmunoassay and FLEXstationTM respectively. Adipocyte glucose-uptake with 3T3-L1 fibroblasts, starch digestion with α–amylase and protein glycation were assessed in vitro. Terminalia arjuna extract stimulated insulin-release alone (p

Original language	English
Pages (from-to)	1001
Journal	Austin Journal of Endocrinology and Diabetes
Volume	1
Issue number	1
Publication status	Published (in print/issue) - 20 Jan 2014

Keywords

Terminalia arjuna
diabetes
insulin
glucose uptake

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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http://austinpublishinggroup.com/endocrinology-diabetes/fulltext/ajed-v1-id1001.php

Cite this

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Thomson, HAJ, Ojo, O, Flatt, P & Abdel-Wahab, YHA 2014, 'Aqueous Bark Extracts of Terminalia Arjuna Stimulates Insulin Release, Enhances Insulin Action and Inhibits Starch Digestion and Protein Glycation in Vitro', Austin Journal of Endocrinology and Diabetes, vol. 1, no. 1, pp. 1001. <http://austinpublishinggroup.com/endocrinology-diabetes/fulltext/ajed-v1-id1001.php>

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T1 - Aqueous Bark Extracts of Terminalia Arjuna Stimulates Insulin Release, Enhances Insulin Action and Inhibits Starch Digestion and Protein Glycation in Vitro

AU - Thomson, HAJ

AU - Ojo, Opeolu

AU - Flatt, Peter

AU - Abdel-Wahab, YHA

PY - 2014/1/20

Y1 - 2014/1/20

N2 - Scientific evidence for the effects of Terminalia arjuna on diabetes mellitus is lacking. This study investigated the anti-diabetic efficacy and mode of action of the bark extract of Terminalia arjuna. Insulin-release from BRIN-BD11 cells was assessed in the absence or presence of T. arjuna extracts and modulators of insulin-secretion. Insulin concentration and intracellular calcium ([Ca2+]i) were measured by radioimmunoassay and FLEXstationTM respectively. Adipocyte glucose-uptake with 3T3-L1 fibroblasts, starch digestion with α–amylase and protein glycation were assessed in vitro. Terminalia arjuna extract stimulated insulin-release alone (p

AB - Scientific evidence for the effects of Terminalia arjuna on diabetes mellitus is lacking. This study investigated the anti-diabetic efficacy and mode of action of the bark extract of Terminalia arjuna. Insulin-release from BRIN-BD11 cells was assessed in the absence or presence of T. arjuna extracts and modulators of insulin-secretion. Insulin concentration and intracellular calcium ([Ca2+]i) were measured by radioimmunoassay and FLEXstationTM respectively. Adipocyte glucose-uptake with 3T3-L1 fibroblasts, starch digestion with α–amylase and protein glycation were assessed in vitro. Terminalia arjuna extract stimulated insulin-release alone (p

KW - Terminalia arjuna

KW - diabetes

KW - insulin

KW - glucose uptake

M3 - Article

SN - 2381-9200

VL - 1

SP - 1001

JO - Austin Journal of Endocrinology and Diabetes

JF - Austin Journal of Endocrinology and Diabetes

IS - 1

ER -

Aqueous Bark Extracts of Terminalia Arjuna Stimulates Insulin Release, Enhances Insulin Action and Inhibits Starch Digestion and Protein Glycation in Vitro

Abstract

Keywords

UN SDGs

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