Application of nanotechnology to herbal antioxidants as improved phytomedicine: An expanding horizon

Yachana Mishra, Hawraz Ibrahim M. Amin, Vijay Mishra, Manish Vyas, Pranav Kumar Prabhakar, Mukta Gupta, Rajeev Kanday, Kalvatala Sudhakar, Sumant Saini, Altijana Hromić-Jahjefendić, Alaa A.A. Aljabali, Mohamed El-Tanani, Ãngel Serrano-Aroca, Hamid Bakshi, Murtaza M. Tambuwala

Research output: Contribution to journalArticlepeer-review

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Abstract

Phytotherapy, based on medicinal plants, have excellent potential in managing several diseases. A vital part of the healthcare system is herbal medicines, consisting of therapeutic agents with high safety profile and no or least adverse effects. Herbs or medicinal plants show anticancer, antioxidant, and gene-protective activity, which is useful for pharmaceutical industries. In vitro, the extract of antioxidant compounds prevents the growth of colon and liver cancer cells, followed by a dose-dependent method. The screening of extracts is done by using in vitro models. Reactive oxygen species (ROS) and free radicals lead to diseases based on age which promotes oxidative stress. Different types of ROSs available have central roles in the normal physiology and functioning of processes. Herbal or traditional plant medicines have rich antioxidant activity. Despite the limited literature on the health effect of herbal extract or spices. There are many studies examining the encouraging health effects of single phytochemicals instigating from the medicinal plant. This review provides a detailed overview on herbal antioxidants and how application of nanotechnology can improve its biological activity in managing several major diseases, and having no reported side effects.
Original languageEnglish
Article number113413
Pages (from-to)1-23
Number of pages23
JournalBiomedicine and Pharmacotherapy
Volume153
Early online date6 Aug 2022
DOIs
Publication statusE-pub ahead of print - 6 Aug 2022

Keywords

  • Herbal antioxidants
  • Oxidative stress
  • Reactive oxygen species
  • Cancer
  • Disease

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