TY - JOUR
T1 - Application of nanotechnology to herbal antioxidants as improved phytomedicine
T2 - An expanding horizon
AU - Mishra, Yachana
AU - Amin, Hawraz Ibrahim M.
AU - Mishra, Vijay
AU - Vyas, Manish
AU - Prabhakar, Pranav Kumar
AU - Gupta, Mukta
AU - Kanday, Rajeev
AU - Sudhakar, Kalvatala
AU - Saini, Sumant
AU - Hromić-Jahjefendić, Altijana
AU - Aljabali, Alaa A.A.
AU - El-Tanani, Mohamed
AU - Serrano-Aroca, Ãngel
AU - Bakshi, Hamid
AU - Tambuwala, Murtaza M.
N1 - Publisher Copyright:
© 2022 The Authors
PY - 2022/9/1
Y1 - 2022/9/1
N2 - Phytotherapy, based on medicinal plants, have excellent potential in managing several diseases. A vital part of the healthcare system is herbal medicines, consisting of therapeutic agents with high safety profile and no or least adverse effects. Herbs or medicinal plants show anticancer, antioxidant, and gene-protective activity, which is useful for pharmaceutical industries. In vitro, the extract of antioxidant compounds prevents the growth of colon and liver cancer cells, followed by a dose-dependent method. The screening of extracts is done by using in vitro models. Reactive oxygen species (ROS) and free radicals lead to diseases based on age which promotes oxidative stress. Different types of ROSs available have central roles in the normal physiology and functioning of processes. Herbal or traditional plant medicines have rich antioxidant activity. Despite the limited literature on the health effect of herbal extract or spices. There are many studies examining the encouraging health effects of single phytochemicals instigating from the medicinal plant. This review provides a detailed overview on herbal antioxidants and how application of nanotechnology can improve its biological activity in managing several major diseases, and having no reported side effects.
AB - Phytotherapy, based on medicinal plants, have excellent potential in managing several diseases. A vital part of the healthcare system is herbal medicines, consisting of therapeutic agents with high safety profile and no or least adverse effects. Herbs or medicinal plants show anticancer, antioxidant, and gene-protective activity, which is useful for pharmaceutical industries. In vitro, the extract of antioxidant compounds prevents the growth of colon and liver cancer cells, followed by a dose-dependent method. The screening of extracts is done by using in vitro models. Reactive oxygen species (ROS) and free radicals lead to diseases based on age which promotes oxidative stress. Different types of ROSs available have central roles in the normal physiology and functioning of processes. Herbal or traditional plant medicines have rich antioxidant activity. Despite the limited literature on the health effect of herbal extract or spices. There are many studies examining the encouraging health effects of single phytochemicals instigating from the medicinal plant. This review provides a detailed overview on herbal antioxidants and how application of nanotechnology can improve its biological activity in managing several major diseases, and having no reported side effects.
KW - Herbal antioxidants
KW - Oxidative stress
KW - Reactive oxygen species
KW - Cancer
KW - Disease
UR - http://www.scopus.com/inward/record.url?scp=85135908870&partnerID=8YFLogxK
U2 - 10.1016/j.biopha.2022.113413
DO - 10.1016/j.biopha.2022.113413
M3 - Article
C2 - 36076482
SN - 0753-3322
VL - 153
SP - 1
EP - 23
JO - Biomedicine and Pharmacotherapy
JF - Biomedicine and Pharmacotherapy
M1 - 113413
ER -
