TY - JOUR
T1 - Antibacterial properties of sophorolipid-modified gold surfaces against Gram positive and Gram negative pathogens.
AU - Valotteau, Claire
AU - Banat, Ibrahim
AU - Mitchell, Christopher
AU - Lydon, Helen
AU - Marchant, Roger
AU - Babonneau, Florence
AU - Pradier, Claire-Marie
AU - Baccile, Niki
AU - Humblot, Vincent
PY - 2017/6/2
Y1 - 2017/6/2
N2 - Sophorolipids are bioderived glycolipids displaying interesting antimicrobial properties.We show that they can be used to develop biocidal monolayers against Listeria ivanovii, aGram-positive bacterium. The present work points out the dependence between thesurface density and the antibacterial activity of grafted sophorolipids. It also emphasizesthe broad spectrum of activity of these coatings, demonstrating their potential againstboth Gram-positive strains (Enteroccocus faecalis, Staphylococcus epidermidis,Streptococcus pyogenes) and Gram-negative strains (Escherichia coli, Pseudomonasaeruginosa and Salmonella typhymurium). After exposure to sophorolipids grafted ontogold, all these bacterial strains show a significant reduction in viability resulting frommembrane damage as evidenced by fluorescent labelling and SEM-FEG analysis.
AB - Sophorolipids are bioderived glycolipids displaying interesting antimicrobial properties.We show that they can be used to develop biocidal monolayers against Listeria ivanovii, aGram-positive bacterium. The present work points out the dependence between thesurface density and the antibacterial activity of grafted sophorolipids. It also emphasizesthe broad spectrum of activity of these coatings, demonstrating their potential againstboth Gram-positive strains (Enteroccocus faecalis, Staphylococcus epidermidis,Streptococcus pyogenes) and Gram-negative strains (Escherichia coli, Pseudomonasaeruginosa and Salmonella typhymurium). After exposure to sophorolipids grafted ontogold, all these bacterial strains show a significant reduction in viability resulting frommembrane damage as evidenced by fluorescent labelling and SEM-FEG analysis.
KW - Biosurfactant
KW - sophorolipid
KW - gold
KW - antibacterial
UR - https://pure.ulster.ac.uk/en/publications/antibacterial-properties-of-sophorolipid-modified-gold-surfaces-a-2
U2 - 10.1016/j.colsurfb.2017.05.072
DO - 10.1016/j.colsurfb.2017.05.072
M3 - Article
C2 - 28609707
SN - 1873-4367
VL - 157
SP - 325
EP - 334
JO - Colloids and Surfaces B: Biointerfaces
JF - Colloids and Surfaces B: Biointerfaces
ER -
