An Overview of Matrix-Assisted Laser Desorption/Ionization (MALDI) Mass Spectrometry and Some of Its Applications

Mark W Duncan; David Gibson; Ryan Walsh; Afsham Massod; Hicham Benabdelkamel

doi:10.1007/978-94-017-9238-7_5

An Overview of Matrix-Assisted Laser Desorption/Ionization (MALDI) Mass Spectrometry and Some of Its Applications

Mark W Duncan
, David Gibson
, Ryan Walsh
, Afsham Massod
, Hicham Benabdelkamel

UCDenver

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

1 Citation (Scopus)

Abstract

Matrix-assisted laser desorption/ionization time-of-flight (TOF) mass spectrometry (MS) is a powerful tool for both the qualitative and quantitative analysis of wide array of analytes. MALDI-TOF MS is simple, both in design and practice, and offers the advantages that analysis times are very short, the mass range is virtually unlimited, and sensitivity is high. This chapter describes the theory and practice of MALDI and illustrates the utility of approach by reviewing its commonapplications.

Original language	English
Title of host publication	Detection of Chemical, Biological, Radiological and Nuclear Agents for the Prevention of Terrorism, NATO Science for Peace and Security Series A: Chemistry and Biology
Place of Publication	Dordrecht, Germany
Publisher	Springer
Pages	69-81
ISBN (Print)	978-94-017-9237-0
DOIs	https://doi.org/10.1007/978-94-017-9238-7_5
Publication status	Published (in print/issue) - 18 Sept 2014

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This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1007/978-94-017-9238-7_5

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Duncan, M. W., Gibson, D., Walsh, R., Massod, A., & Benabdelkamel, H. (2014). An Overview of Matrix-Assisted Laser Desorption/Ionization (MALDI) Mass Spectrometry and Some of Its Applications. In Detection of Chemical, Biological, Radiological and Nuclear Agents for the Prevention of Terrorism, NATO Science for Peace and Security Series A: Chemistry and Biology (pp. 69-81). Springer. https://doi.org/10.1007/978-94-017-9238-7_5

Duncan, Mark W ; Gibson, David ; Walsh, Ryan et al. / An Overview of Matrix-Assisted Laser Desorption/Ionization (MALDI) Mass Spectrometry and Some of Its Applications. Detection of Chemical, Biological, Radiological and Nuclear Agents for the Prevention of Terrorism, NATO Science for Peace and Security Series A: Chemistry and Biology. Dordrecht, Germany : Springer, 2014. pp. 69-81

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Duncan, MW, Gibson, D, Walsh, R, Massod, A & Benabdelkamel, H 2014, An Overview of Matrix-Assisted Laser Desorption/Ionization (MALDI) Mass Spectrometry and Some of Its Applications. in Detection of Chemical, Biological, Radiological and Nuclear Agents for the Prevention of Terrorism, NATO Science for Peace and Security Series A: Chemistry and Biology. Springer, Dordrecht, Germany, pp. 69-81. https://doi.org/10.1007/978-94-017-9238-7_5

An Overview of Matrix-Assisted Laser Desorption/Ionization (MALDI) Mass Spectrometry and Some of Its Applications. / Duncan, Mark W; Gibson, David; Walsh, Ryan et al.
Detection of Chemical, Biological, Radiological and Nuclear Agents for the Prevention of Terrorism, NATO Science for Peace and Security Series A: Chemistry and Biology. Dordrecht, Germany: Springer, 2014. p. 69-81.

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

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PY - 2014/9/18

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AB - Matrix-assisted laser desorption/ionization time-of-flight (TOF) mass spectrometry (MS) is a powerful tool for both the qualitative and quantitative analysis of wide array of analytes. MALDI-TOF MS is simple, both in design and practice, and offers the advantages that analysis times are very short, the mass range is virtually unlimited, and sensitivity is high. This chapter describes the theory and practice of MALDI and illustrates the utility of approach by reviewing its commonapplications.

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EP - 81

BT - Detection of Chemical, Biological, Radiological and Nuclear Agents for the Prevention of Terrorism, NATO Science for Peace and Security Series A: Chemistry and Biology

PB - Springer

CY - Dordrecht, Germany

ER -

Duncan MW, Gibson D, Walsh R, Massod A, Benabdelkamel H. An Overview of Matrix-Assisted Laser Desorption/Ionization (MALDI) Mass Spectrometry and Some of Its Applications. In Detection of Chemical, Biological, Radiological and Nuclear Agents for the Prevention of Terrorism, NATO Science for Peace and Security Series A: Chemistry and Biology. Dordrecht, Germany: Springer. 2014. p. 69-81 doi: 10.1007/978-94-017-9238-7_5

An Overview of Matrix-Assisted Laser Desorption/Ionization (MALDI) Mass Spectrometry and Some of Its Applications

Abstract

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