An Appraisal of the Current Scenario in Vaccine Research for COVID-19

Wai Chin Chong, Dinesh K. Chellappan, Shakti D. Shukla, Gregory M. Peterson, Rahul P. Patel, Niraj Kumar Jha, Rajaraman D. Eri, Kamal Dua, Murtaza M. Tambuwala, Madhur D. Shastri

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Abstract

The recent coronavirus disease 2019 (COVID-19) outbreak has drawn global attention, affecting millions, disrupting economies and healthcare modalities. With its high infection rate, COVID-19 has caused a colossal health crisis worldwide. While information on the comprehensive nature of this infectious agent, SARS-CoV-2, still remains obscure, ongoing genomic studies have been successful in identifying its genomic sequence and the presenting antigen. These may serve as promising, potential therapeutic targets in the effective management of COVID-19. In an attempt to establish herd immunity, massive efforts have been directed and driven toward developing vaccines against the SARS-CoV-2 pathogen. This review, in this direction, is aimed at providing the current scenario and future perspectives in the development of vaccines against SARS-CoV-2.
Original languageEnglish
Article numbere1397
JournalViruses
Volume13
Issue number7
Early online date18 Jul 2021
DOIs
Publication statusE-pub ahead of print - 18 Jul 2021

Keywords

  • COVID-19
  • SARS-CoV-2
  • vaccines
  • therapeutic targets
  • immunity

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