Allosteric Modulation of the Calcium-sensing Receptor Rectifies Signaling Abnormalities Associated with G-protein α-11 Mutations Causing Hypercalcemic and Hypocalcemic Disorders

Valerie N. Babinsky; Fadil M. Hannan; Caroline M. Gorvin; Sarah A. Howles; M. Andrew Nesbit; Nigel Rust; Aylin C. Hanyaloglu; Jianxin Hu; Allen M. Spiegel; Rajesh V. Thakker

doi:10.1074/jbc.M115.696401

Allosteric Modulation of the Calcium-sensing Receptor Rectifies Signaling Abnormalities Associated with G-protein α-11 Mutations Causing Hypercalcemic and Hypocalcemic Disorders

Valerie N. Babinsky, Fadil M. Hannan, Caroline M. Gorvin, Sarah A. Howles, M. Andrew Nesbit, Nigel Rust, Aylin C. Hanyaloglu, Jianxin Hu, Allen M. Spiegel, Rajesh V. Thakker

Research output: Contribution to journal › Article › peer-review

37 Citations (Scopus)

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Original language	English
Pages (from-to)	10876-10885
Journal	Journal of Biological Chemistry
Volume	291
Issue number	20
DOIs	https://doi.org/10.1074/jbc.M115.696401
Publication status	Published (in print/issue) - 13 May 2016

Keywords

Calcium-sensing Receptor
Hypercalcaemia
hypocalcaemia

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1074/jbc.M115.696401

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Babinsky, V. N., Hannan, F. M., Gorvin, C. M., Howles, S. A., Nesbit, M. A., Rust, N., Hanyaloglu, A. C., Hu, J., Spiegel, A. M., & Thakker, R. V. (2016). Allosteric Modulation of the Calcium-sensing Receptor Rectifies Signaling Abnormalities Associated with G-protein α-11 Mutations Causing Hypercalcemic and Hypocalcemic Disorders. Journal of Biological Chemistry, 291(20), 10876-10885. https://doi.org/10.1074/jbc.M115.696401

@article{36678fcacbfd4d35bc103e2e0ea045a8,

title = "Allosteric Modulation of the Calcium-sensing Receptor Rectifies Signaling Abnormalities Associated with G-protein α-11 Mutations Causing Hypercalcemic and Hypocalcemic Disorders",

keywords = "Calcium-sensing Receptor, Hypercalcaemia, hypocalcaemia",

author = "Babinsky, \{Valerie N.\} and Hannan, \{Fadil M.\} and Gorvin, \{Caroline M.\} and Howles, \{Sarah A.\} and Nesbit, \{M. Andrew\} and Nigel Rust and Hanyaloglu, \{Aylin C.\} and Jianxin Hu and Spiegel, \{Allen M.\} and Thakker, \{Rajesh V.\}",

year = "2016",

month = may,

day = "13",

doi = "10.1074/jbc.M115.696401",

language = "English",

volume = "291",

pages = "10876--10885",

journal = "Journal of Biological Chemistry",

issn = "1083-351",

publisher = "American Society for Biochemistry and Molecular Biology",

number = "20",

}

Babinsky, VN, Hannan, FM, Gorvin, CM, Howles, SA, Nesbit, MA, Rust, N, Hanyaloglu, AC, Hu, J, Spiegel, AM & Thakker, RV 2016, 'Allosteric Modulation of the Calcium-sensing Receptor Rectifies Signaling Abnormalities Associated with G-protein α-11 Mutations Causing Hypercalcemic and Hypocalcemic Disorders', Journal of Biological Chemistry, vol. 291, no. 20, pp. 10876-10885. https://doi.org/10.1074/jbc.M115.696401

Allosteric Modulation of the Calcium-sensing Receptor Rectifies Signaling Abnormalities Associated with G-protein α-11 Mutations Causing Hypercalcemic and Hypocalcemic Disorders. / Babinsky, Valerie N.; Hannan, Fadil M.; Gorvin, Caroline M. et al.
In: Journal of Biological Chemistry, Vol. 291, No. 20, 13.05.2016, p. 10876-10885.

Research output: Contribution to journal › Article › peer-review

TY - JOUR

T1 - Allosteric Modulation of the Calcium-sensing Receptor Rectifies Signaling Abnormalities Associated with G-protein α-11 Mutations Causing Hypercalcemic and Hypocalcemic Disorders

AU - Babinsky, Valerie N.

AU - Hannan, Fadil M.

AU - Gorvin, Caroline M.

AU - Howles, Sarah A.

AU - Nesbit, M. Andrew

AU - Rust, Nigel

AU - Hanyaloglu, Aylin C.

AU - Hu, Jianxin

AU - Spiegel, Allen M.

AU - Thakker, Rajesh V.

PY - 2016/5/13

Y1 - 2016/5/13

KW - Calcium-sensing Receptor

KW - Hypercalcaemia

KW - hypocalcaemia

UR - https://www.scopus.com/pages/publications/84969249055

U2 - 10.1074/jbc.M115.696401

DO - 10.1074/jbc.M115.696401

M3 - Article

SN - 1083-351

VL - 291

SP - 10876

EP - 10885

JO - Journal of Biological Chemistry

JF - Journal of Biological Chemistry

IS - 20

ER -

Allosteric Modulation of the Calcium-sensing Receptor Rectifies Signaling Abnormalities Associated with G-protein α-11 Mutations Causing Hypercalcemic and Hypocalcemic Disorders

Keywords

UN SDGs

Access to Document

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