Allosteric Modulation of the Calcium-sensing Receptor Rectifies Signaling Abnormalities Associated with G-protein α-11 Mutations Causing Hypercalcemic and Hypocalcemic Disorders

Valerie N. Babinsky; Fadil M. Hannan; Caroline M. Gorvin; Sarah A. Howles; M. Andrew Nesbit; Nigel Rust; Aylin C. Hanyaloglu; Jianxin Hu; Allen M. Spiegel; Rajesh V. Thakker

doi:10.1074/jbc.M115.696401

Allosteric Modulation of the Calcium-sensing Receptor Rectifies Signaling Abnormalities Associated with G-protein α-11 Mutations Causing Hypercalcemic and Hypocalcemic Disorders

Valerie N. Babinsky, Fadil M. Hannan, Caroline M. Gorvin, Sarah A. Howles, M. Andrew Nesbit, Nigel Rust, Aylin C. Hanyaloglu, Jianxin Hu, Allen M. Spiegel, Rajesh V. Thakker

Research output: Contribution to journal › Article › peer-review

34 Citations (Scopus)

61 Downloads (Pure)

Original language	English
Pages (from-to)	10876-10885
Journal	Journal of Biological Chemistry
Volume	291
Issue number	20
DOIs	https://doi.org/10.1074/jbc.M115.696401
Publication status	Published (in print/issue) - 13 May 2016

Keywords

Calcium-sensing Receptor
Hypercalcaemia
hypocalcaemia

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This output contributes to the following UN Sustainable Development Goals (SDGs)

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Cite this

Babinsky, V. N., Hannan, F. M., Gorvin, C. M., Howles, S. A., Nesbit, M. A., Rust, N., Hanyaloglu, A. C., Hu, J., Spiegel, A. M., & Thakker, R. V. (2016). Allosteric Modulation of the Calcium-sensing Receptor Rectifies Signaling Abnormalities Associated with G-protein α-11 Mutations Causing Hypercalcemic and Hypocalcemic Disorders. Journal of Biological Chemistry, 291(20), 10876-10885. https://doi.org/10.1074/jbc.M115.696401

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keywords = "Calcium-sensing Receptor, Hypercalcaemia, hypocalcaemia",

author = "Babinsky, {Valerie N.} and Hannan, {Fadil M.} and Gorvin, {Caroline M.} and Howles, {Sarah A.} and Nesbit, {M. Andrew} and Nigel Rust and Hanyaloglu, {Aylin C.} and Jianxin Hu and Spiegel, {Allen M.} and Thakker, {Rajesh V.}",

year = "2016",

month = may,

day = "13",

doi = "10.1074/jbc.M115.696401",

language = "English",

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journal = "Journal of Biological Chemistry",

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Babinsky, VN, Hannan, FM, Gorvin, CM, Howles, SA, Nesbit, MA, Rust, N, Hanyaloglu, AC, Hu, J, Spiegel, AM & Thakker, RV 2016, 'Allosteric Modulation of the Calcium-sensing Receptor Rectifies Signaling Abnormalities Associated with G-protein α-11 Mutations Causing Hypercalcemic and Hypocalcemic Disorders', Journal of Biological Chemistry, vol. 291, no. 20, pp. 10876-10885. https://doi.org/10.1074/jbc.M115.696401

Allosteric Modulation of the Calcium-sensing Receptor Rectifies Signaling Abnormalities Associated with G-protein α-11 Mutations Causing Hypercalcemic and Hypocalcemic Disorders. / Babinsky, Valerie N.; Hannan, Fadil M.; Gorvin, Caroline M. et al.
In: Journal of Biological Chemistry, Vol. 291, No. 20, 13.05.2016, p. 10876-10885.

Research output: Contribution to journal › Article › peer-review

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T1 - Allosteric Modulation of the Calcium-sensing Receptor Rectifies Signaling Abnormalities Associated with G-protein α-11 Mutations Causing Hypercalcemic and Hypocalcemic Disorders

AU - Babinsky, Valerie N.

AU - Hannan, Fadil M.

AU - Gorvin, Caroline M.

AU - Howles, Sarah A.

AU - Nesbit, M. Andrew

AU - Rust, Nigel

AU - Hanyaloglu, Aylin C.

AU - Hu, Jianxin

AU - Spiegel, Allen M.

AU - Thakker, Rajesh V.

PY - 2016/5/13

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KW - Calcium-sensing Receptor

KW - Hypercalcaemia

KW - hypocalcaemia

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