Allosteric Modulation of the Calcium-sensing Receptor Rectifies Signaling Abnormalities Associated with G-protein α-11 Mutations Causing Hypercalcemic and Hypocalcemic Disorders

Valerie N. Babinsky, Fadil M. Hannan, Caroline M. Gorvin, Sarah A. Howles, M. Andrew Nesbit, Nigel Rust, Aylin C. Hanyaloglu, Jianxin Hu, Allen M. Spiegel, Rajesh V. Thakker

Research output: Contribution to journalArticlepeer-review

34 Citations (Scopus)
49 Downloads (Pure)
Original languageEnglish
Pages (from-to)10876-10885
JournalJournal of Biological Chemistry
Issue number20
Publication statusPublished (in print/issue) - 13 May 2016


  • Calcium-sensing Receptor
  • Hypercalcaemia
  • hypocalcaemia

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