Algorithms for digital image processing in diabetic retinopathy

John Winder, Philip Morrow, I. N. McRitchie, J. R. Bailie, P. M. Hart

Research output: Contribution to journalArticlepeer-review

227 Citations (Scopus)


This work examined recent literature on digital image processing in the field of diabetic retinopathy. Algorithms were categorized into 5 steps (preprocessing; localization and segmentation of the optic disk; segmentation of the retinal vasculature; localization of the macula and fovea; localization and segmentation of retinopathy). The variety of outcome measures, use of a gold standard or ground truth, data sample sizes and the use of image databases is discussed. It is intended that our classification of algorithms into a small number of categories, definition of terms and discussion of evolving techniques will provide guidance to algorithm designers for diabetic retinopathy. (C) 2009 Elsevier Ltd. All rights reserved.
Original languageEnglish
Pages (from-to)608-622
JournalComputerized Medical Imaging and Graphics
Issue number8
Publication statusPublished (in print/issue) - Dec 2009


  • Diabetic retinopathy
  • Computer-aided diagnosis
  • Digital imaging
  • Image processing


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