TY - JOUR
T1 - Ag-silica composite nanotube with controlled wall structures for biomedical applications
AU - He, Haiyan
AU - Wang, Juan
AU - Gao, Qian
AU - Chang, Mingwei
AU - Ren, Zhaohui
AU - Zhang, Xiwen
AU - Li, Xiang
AU - Weng, Wenjian
AU - Han, Gaorong
PY - 2013/11/1
Y1 - 2013/11/1
N2 - A range of Ag-silica composite nanotubes with tailored wall structures were successfully synthesized in situ by single-nozzle electrospinning. By increasing AgNO3 concentration, the wall structure of Ag-silica tubes changes from dense to porous, and eventually turns into a 'lace-like' structure. This is attributed to Ag ions doping into the SiOSi network of precursors, as illustrated in FTIR study. More importantly, Ag-silica composite nanotubes show robust antibacterial activity against both Gram-positive Staphylococcus aureus and Gram-negative Escherichia coli microorganisms. Therefore, it is a breakthrough of the nanostructure biomaterial research for future medical applications that require strong antibacterial properties.
AB - A range of Ag-silica composite nanotubes with tailored wall structures were successfully synthesized in situ by single-nozzle electrospinning. By increasing AgNO3 concentration, the wall structure of Ag-silica tubes changes from dense to porous, and eventually turns into a 'lace-like' structure. This is attributed to Ag ions doping into the SiOSi network of precursors, as illustrated in FTIR study. More importantly, Ag-silica composite nanotubes show robust antibacterial activity against both Gram-positive Staphylococcus aureus and Gram-negative Escherichia coli microorganisms. Therefore, it is a breakthrough of the nanostructure biomaterial research for future medical applications that require strong antibacterial properties.
KW - Ag-silica nanotube
KW - Antibacterial
KW - Controlled wall-structure
KW - Electrospinning
UR - http://www.scopus.com/inward/record.url?scp=84881256214&partnerID=8YFLogxK
U2 - 10.1016/j.colsurfb.2013.07.015
DO - 10.1016/j.colsurfb.2013.07.015
M3 - Article
C2 - 23907057
AN - SCOPUS:84881256214
SN - 0927-7765
VL - 111
SP - 693
EP - 698
JO - Colloids and Surfaces B: Biointerfaces
JF - Colloids and Surfaces B: Biointerfaces
ER -