Ag-silica composite nanotube with controlled wall structures for biomedical applications

Haiyan He, Juan Wang, Qian Gao, Mingwei Chang, Zhaohui Ren, Xiwen Zhang, Xiang Li, Wenjian Weng, Gaorong Han

Research output: Contribution to journalArticlepeer-review

10 Citations (Scopus)


A range of Ag-silica composite nanotubes with tailored wall structures were successfully synthesized in situ by single-nozzle electrospinning. By increasing AgNO3 concentration, the wall structure of Ag-silica tubes changes from dense to porous, and eventually turns into a 'lace-like' structure. This is attributed to Ag ions doping into the SiOSi network of precursors, as illustrated in FTIR study. More importantly, Ag-silica composite nanotubes show robust antibacterial activity against both Gram-positive Staphylococcus aureus and Gram-negative Escherichia coli microorganisms. Therefore, it is a breakthrough of the nanostructure biomaterial research for future medical applications that require strong antibacterial properties.

Original languageEnglish
Pages (from-to)693-698
Number of pages6
JournalColloids and Surfaces B: Biointerfaces
Publication statusPublished (in print/issue) - 1 Nov 2013


  • Ag-silica nanotube
  • Antibacterial
  • Controlled wall-structure
  • Electrospinning


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