Advances on the use of carbon based materials at the biological and surface interface for applications in medical implants

Research output: Contribution to journalArticle

Abstract

One of the setbacks of vascular stents is the potential development of a thick-smooth muscle tissue inside the lumen, which can be so severe as to re-occlude the vessel lumen leading to restenosis. Considerable improvements have been made, including the use of more bio-compatible materials, anti-inflammatory drug-eluting stents, re-sorbable stents, and now plasma coatings are being recognised as a potential way forward. This paper describes the role of 3-D plasma coatings of amorphous carbon and in particular low-stress a-C:H:Si overlayers. The high barrier nature of the amorphous carbon coating is examined by measuring oxygen and water diffusion across the ultra thin film. The stent coating is analysed by Raman Spectroscopy and the ID/IG ratio relates to the coating quality differences inside and outside of the stent cage. Published by Elsevier B.V.
LanguageEnglish
Pages873-877
JournalDiamond and Related Materials
Volume17
Issue number4-5, S
Early online date1 Nov 2007
DOIs
Publication statusPublished - Apr 2008

Fingerprint

Stents
Carbon
Coatings
Amorphous carbon
Plasmas
Ultrathin films
Biomaterials
Muscle
Raman spectroscopy
Anti-Inflammatory Agents
Tissue
Oxygen
Water
Pharmaceutical Preparations

Keywords

  • stent
  • amorphous carbon
  • plasma coated
  • medical device

Cite this

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title = "Advances on the use of carbon based materials at the biological and surface interface for applications in medical implants",
abstract = "One of the setbacks of vascular stents is the potential development of a thick-smooth muscle tissue inside the lumen, which can be so severe as to re-occlude the vessel lumen leading to restenosis. Considerable improvements have been made, including the use of more bio-compatible materials, anti-inflammatory drug-eluting stents, re-sorbable stents, and now plasma coatings are being recognised as a potential way forward. This paper describes the role of 3-D plasma coatings of amorphous carbon and in particular low-stress a-C:H:Si overlayers. The high barrier nature of the amorphous carbon coating is examined by measuring oxygen and water diffusion across the ultra thin film. The stent coating is analysed by Raman Spectroscopy and the ID/IG ratio relates to the coating quality differences inside and outside of the stent cage. Published by Elsevier B.V.",
keywords = "stent, amorphous carbon, plasma coated, medical device",
author = "JAD McLaughlin and PD Maguire",
note = "International Conference on New Diamond and Nano Carbons, Osaka, JAPAN, MAY 28-31, 2007",
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AU - Maguire, PD

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AB - One of the setbacks of vascular stents is the potential development of a thick-smooth muscle tissue inside the lumen, which can be so severe as to re-occlude the vessel lumen leading to restenosis. Considerable improvements have been made, including the use of more bio-compatible materials, anti-inflammatory drug-eluting stents, re-sorbable stents, and now plasma coatings are being recognised as a potential way forward. This paper describes the role of 3-D plasma coatings of amorphous carbon and in particular low-stress a-C:H:Si overlayers. The high barrier nature of the amorphous carbon coating is examined by measuring oxygen and water diffusion across the ultra thin film. The stent coating is analysed by Raman Spectroscopy and the ID/IG ratio relates to the coating quality differences inside and outside of the stent cage. Published by Elsevier B.V.

KW - stent

KW - amorphous carbon

KW - plasma coated

KW - medical device

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