Addressing the Silent Spread of Monkeypox Disease with Advanced Analytical Tools

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Monkeypox disease is caused by a virus which belongs to the orthopoxvirus genus of the poxviridae family. This disease has recently spread out to several non‐endemic countries. While some cases have been linked to travel from endemic regions, more recent infections are thought to have spread in the community without any travel links, raising the risks of a wider outbreak. This state of public health represents a highly unusual event which requires urgent surveillance. In this context, the opportunities and technological challenges of current bio/chemical sensors, nanomaterials, nanomaterial characterization instruments, and artificially intelligent biosystems collectively called “advanced analytical tools” are reviewed here, which will allow early detection, characterization, and inhibition of the monkeypox virus (MPXV) in the community and limit its expansion from endemic to pandemic. A summary of background information is also provided from biological and epidemiological perspective of monkeypox to support the scientific case for its holistic management using advanced analytical tools.
Original languageEnglish
Article number2206633
Pages (from-to)1-24
Number of pages24
Issue number9
Early online date14 Dec 2022
Publication statusPublished (in print/issue) - 1 Mar 2023

Bibliographical note

Publisher Copyright:
© 2022 The Authors. Small published by Wiley-VCH GmbH.


  • Review
  • Reviews
  • atomic force microscopy
  • biosensors
  • monkeypox
  • nanomaterials
  • viruses


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