A new fluorescent chemosensor for iron(III) based on the beta-aminobisulfonate receptor

Narinder Singh; Navneet Kaur; John Dunn; Martha MacKay; John F. Callan

doi:10.1016/j.tetlet.2008.12.041

A new fluorescent chemosensor for iron(III) based on the beta-aminobisulfonate receptor

Narinder Singh
, Navneet Kaur
, John Dunn
, Martha MacKay
, John F. Callan

Biomedical Sciences Research

Research output: Contribution to journal › Article › peer-review

91 Citations (Scopus)

Abstract

A simple fluorescent sensor 1 has been developed for the determination of Fe(III) in 100% aqueous solution at pH 7.0. The sensor comprises a novel aminobisulfonate receptor joined to a naphthalene fluorophore via a methylene spacer in the fluorophore-spacer-receptor format of photoinduced electron transfer (PET) based sensors. The fluorescence emission of the sensor was quenched upon addition of Fe(III) ions, most likely due to electron/energy transfer between Fe(III) and the excited naphthalene. The sensor displayed good selectivity for Fe(III) over other physiologically relevant metal ions and can estimate Fe(III) concentration between 16 and 63 mu M. Stern Volmer analysis showed the binding stoichiometry to be 1:1 (host-guest) with a binding constant, calculated using the Benesi-Hilderbrand equation, of (7.6 +/- 0.6) x 10(4) M(-1). (C) 2009 Elsevier Ltd. All rights reserved.

Original language	English
Pages (from-to)	953-956
Journal	Tetrahedron Letters
Volume	50
Issue number	8
DOIs	https://doi.org/10.1016/j.tetlet.2008.12.041
Publication status	Published (in print/issue) - Feb 2009

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title = "A new fluorescent chemosensor for iron(III) based on the beta-aminobisulfonate receptor",

abstract = "A simple fluorescent sensor 1 has been developed for the determination of Fe(III) in 100\% aqueous solution at pH 7.0. The sensor comprises a novel aminobisulfonate receptor joined to a naphthalene fluorophore via a methylene spacer in the fluorophore-spacer-receptor format of photoinduced electron transfer (PET) based sensors. The fluorescence emission of the sensor was quenched upon addition of Fe(III) ions, most likely due to electron/energy transfer between Fe(III) and the excited naphthalene. The sensor displayed good selectivity for Fe(III) over other physiologically relevant metal ions and can estimate Fe(III) concentration between 16 and 63 mu M. Stern Volmer analysis showed the binding stoichiometry to be 1:1 (host-guest) with a binding constant, calculated using the Benesi-Hilderbrand equation, of (7.6 +/- 0.6) x 10(4) M(-1). (C) 2009 Elsevier Ltd. All rights reserved.",

author = "Narinder Singh and Navneet Kaur and John Dunn and Martha MacKay and Callan, \{John F.\}",

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T1 - A new fluorescent chemosensor for iron(III) based on the beta-aminobisulfonate receptor

AU - Singh, Narinder

AU - Kaur, Navneet

AU - Dunn, John

AU - MacKay, Martha

AU - Callan, John F.

PY - 2009/2

Y1 - 2009/2

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AB - A simple fluorescent sensor 1 has been developed for the determination of Fe(III) in 100% aqueous solution at pH 7.0. The sensor comprises a novel aminobisulfonate receptor joined to a naphthalene fluorophore via a methylene spacer in the fluorophore-spacer-receptor format of photoinduced electron transfer (PET) based sensors. The fluorescence emission of the sensor was quenched upon addition of Fe(III) ions, most likely due to electron/energy transfer between Fe(III) and the excited naphthalene. The sensor displayed good selectivity for Fe(III) over other physiologically relevant metal ions and can estimate Fe(III) concentration between 16 and 63 mu M. Stern Volmer analysis showed the binding stoichiometry to be 1:1 (host-guest) with a binding constant, calculated using the Benesi-Hilderbrand equation, of (7.6 +/- 0.6) x 10(4) M(-1). (C) 2009 Elsevier Ltd. All rights reserved.

U2 - 10.1016/j.tetlet.2008.12.041

DO - 10.1016/j.tetlet.2008.12.041

M3 - Article

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EP - 956

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 8

ER -

A new fluorescent chemosensor for iron(III) based on the beta-aminobisulfonate receptor

Abstract

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