A network analysis of DSM-5 posttraumatic stress disorder symptoms and correlates in U.S. military veterans

C Armour, Eiko I. Fried, Marie K. Deserno, Jack Tsai, Robert H. Pietrzak

Research output: Contribution to journalArticle

48 Citations (Scopus)

Abstract

Objective
Recent developments in psychometrics enable the application of network models to analyze psychological disorders, such as PTSD. Instead of understanding symptoms as indicators of an underlying common cause, this approach suggests symptoms co-occur in syndromes due to causal interactions. The current study has two goals: (1) examine the network structure among the 20 DSM-5 PTSD symptoms, and (2) incorporate clinically relevant variables to the network to investigate whether PTSD symptoms exhibit differential relationships with suicidal ideation, depression, anxiety, physical functioning/quality of life (QoL), mental functioning/QoL, age, and sex.

Method
We utilized a nationally representative U.S. military veteran’s sample; and analyzed the data from a subsample of 221 veterans who reported clinically significant DSM-5 PTSD symptoms. Networks were estimated using state-of-the-art regularized partial correlation models. Data and code are published along with the paper.

Results
The 20-item DSM-5 PTSD network revealed that symptoms were positively connected within the network. Especially strong connections emerged between nightmares and flashbacks; blame of self or others and negative trauma-related emotions, detachment and restricted affect; and hypervigilance and exaggerated startle response. The most central symptoms were negative trauma-related emotions, flashbacks, detachment, and physiological cue reactivity. Incorporation of clinically relevant covariates into the network revealed paths between self-destructive behavior and suicidal ideation; concentration difficulties and anxiety, depression, and mental QoL; and depression and restricted affect.

Conclusion
These results demonstrate the utility of a network approach in modeling the structure of DSM-5 PTSD symptoms, and suggest differential associations between specific DSM-5 PTSD symptoms and clinical outcomes in trauma survivors. Implications of these results for informing the assessment and treatment of this disorder, are discussed.
LanguageEnglish
Pages49-59
Number of pages10
JournalJournal of Anxiety Disorders
Volume45
Early online date27 Nov 2016
DOIs
Publication statusPublished - Jan 2017

Fingerprint

Veterans
Post-Traumatic Stress Disorders
Suicidal Ideation
Anxiety
Quality of Life
Depression
Wounds and Injuries
Startle Reflex
Emotions
Self-Injurious Behavior
Ego
Psychometrics
Cues
Survivors
Psychology

Keywords

  • PTSD
  • Depression
  • DSM-5
  • Veterans
  • Network analysis
  • Functioning
  • Quality of Life
  • Suicide

Cite this

Armour, C ; Fried, Eiko I. ; Deserno, Marie K. ; Tsai, Jack ; Pietrzak, Robert H. / A network analysis of DSM-5 posttraumatic stress disorder symptoms and correlates in U.S. military veterans. In: Journal of Anxiety Disorders. 2017 ; Vol. 45. pp. 49-59.
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abstract = "ObjectiveRecent developments in psychometrics enable the application of network models to analyze psychological disorders, such as PTSD. Instead of understanding symptoms as indicators of an underlying common cause, this approach suggests symptoms co-occur in syndromes due to causal interactions. The current study has two goals: (1) examine the network structure among the 20 DSM-5 PTSD symptoms, and (2) incorporate clinically relevant variables to the network to investigate whether PTSD symptoms exhibit differential relationships with suicidal ideation, depression, anxiety, physical functioning/quality of life (QoL), mental functioning/QoL, age, and sex.MethodWe utilized a nationally representative U.S. military veteran’s sample; and analyzed the data from a subsample of 221 veterans who reported clinically significant DSM-5 PTSD symptoms. Networks were estimated using state-of-the-art regularized partial correlation models. Data and code are published along with the paper.ResultsThe 20-item DSM-5 PTSD network revealed that symptoms were positively connected within the network. Especially strong connections emerged between nightmares and flashbacks; blame of self or others and negative trauma-related emotions, detachment and restricted affect; and hypervigilance and exaggerated startle response. The most central symptoms were negative trauma-related emotions, flashbacks, detachment, and physiological cue reactivity. Incorporation of clinically relevant covariates into the network revealed paths between self-destructive behavior and suicidal ideation; concentration difficulties and anxiety, depression, and mental QoL; and depression and restricted affect.ConclusionThese results demonstrate the utility of a network approach in modeling the structure of DSM-5 PTSD symptoms, and suggest differential associations between specific DSM-5 PTSD symptoms and clinical outcomes in trauma survivors. Implications of these results for informing the assessment and treatment of this disorder, are discussed.",
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A network analysis of DSM-5 posttraumatic stress disorder symptoms and correlates in U.S. military veterans. / Armour, C; Fried, Eiko I.; Deserno, Marie K.; Tsai, Jack; Pietrzak, Robert H.

In: Journal of Anxiety Disorders, Vol. 45, 01.2017, p. 49-59.

Research output: Contribution to journalArticle

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N2 - ObjectiveRecent developments in psychometrics enable the application of network models to analyze psychological disorders, such as PTSD. Instead of understanding symptoms as indicators of an underlying common cause, this approach suggests symptoms co-occur in syndromes due to causal interactions. The current study has two goals: (1) examine the network structure among the 20 DSM-5 PTSD symptoms, and (2) incorporate clinically relevant variables to the network to investigate whether PTSD symptoms exhibit differential relationships with suicidal ideation, depression, anxiety, physical functioning/quality of life (QoL), mental functioning/QoL, age, and sex.MethodWe utilized a nationally representative U.S. military veteran’s sample; and analyzed the data from a subsample of 221 veterans who reported clinically significant DSM-5 PTSD symptoms. Networks were estimated using state-of-the-art regularized partial correlation models. Data and code are published along with the paper.ResultsThe 20-item DSM-5 PTSD network revealed that symptoms were positively connected within the network. Especially strong connections emerged between nightmares and flashbacks; blame of self or others and negative trauma-related emotions, detachment and restricted affect; and hypervigilance and exaggerated startle response. The most central symptoms were negative trauma-related emotions, flashbacks, detachment, and physiological cue reactivity. Incorporation of clinically relevant covariates into the network revealed paths between self-destructive behavior and suicidal ideation; concentration difficulties and anxiety, depression, and mental QoL; and depression and restricted affect.ConclusionThese results demonstrate the utility of a network approach in modeling the structure of DSM-5 PTSD symptoms, and suggest differential associations between specific DSM-5 PTSD symptoms and clinical outcomes in trauma survivors. Implications of these results for informing the assessment and treatment of this disorder, are discussed.

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