A Clear, Delicate, Biocompatible Optical Window for Brain Imaging

Srinivasu Puttaswamy; Aishwarya  Bandla; Sam Fishlock; Chengkuo  Lee; James McLaughlin

doi:10.1109/NANO.2018.8626270

A Clear, Delicate, Biocompatible Optical Window for Brain Imaging

Srinivasu Puttaswamy, Aishwarya Bandla, Sam Fishlock, Chengkuo Lee, James McLaughlin

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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Abstract

In this work, we present a single-step method to fabricate transparent, flexible optical windows of biocompatible hydrogel material for repeated, long-term
optical recordings and stroke monitoring of rodent cortex. The main advantage of the proposed method is that the optical window of any desired shape and size can be conveniently fabricated in a short span of time. The fabrication of the optical window is simple and completed in a single step. Biocompatible hydrogel poly (ethylene glycol) diacrylate (PEGDA) in the liquid form before curing conforms well to the required shape and size after cross linking. Being a light, transparent and stretchable material provide a practical solution to long- term optical imaging in the anesthetized rat.

Original language	English
Title of host publication	18th International Conference on Nanotechnology, NANO 2018
Place of Publication	Cork
Volume	2018-July
ISBN (Electronic)	9781538653364
DOIs	https://doi.org/10.1109/NANO.2018.8626270
Publication status	Published (in print/issue) - 24 Jan 2019

Keywords

Optical Window
Brain Imaging

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10.1109/NANO.2018.8626270

A Clear, Delicate, Biocompatible Optical Window for Brain ImagingFinal published version, 356 KB

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1 Article

Versatile microfluidic platform embedded with sidewall three-dimensional electrodes for cell manipulation
Puttaswamy, S., Fishlock, S., Steele, D., Shi, Q., Lee, C. & McLaughlin, J., 7 Aug 2019, In: Biomedical Physics & Engineering Express. 5, 5, p. 1-37 37 p.
Research output: Contribution to journal › Article › peer-review

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Cite this

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title = "A Clear, Delicate, Biocompatible Optical Window for Brain Imaging",

abstract = "In this work, we present a single-step method to fabricate transparent, flexible optical windows of biocompatible hydrogel material for repeated, long-term optical recordings and stroke monitoring of rodent cortex. The main advantage of the proposed method is that the optical window of any desired shape and size can be conveniently fabricated in a short span of time. The fabrication of the optical window is simple and completed in a single step. Biocompatible hydrogel poly (ethylene glycol) diacrylate (PEGDA) in the liquid form before curing conforms well to the required shape and size after cross linking. Being a light, transparent and stretchable material provide a practical solution to long- term optical imaging in the anesthetized rat. ",

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author = "Srinivasu Puttaswamy and Aishwarya Bandla and Sam Fishlock and Chengkuo Lee and James McLaughlin",

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language = "English",

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AU - Puttaswamy, Srinivasu

AU - Bandla, Aishwarya

AU - Fishlock, Sam

AU - Lee, Chengkuo

AU - McLaughlin, James

PY - 2019/1/24

Y1 - 2019/1/24

N2 - In this work, we present a single-step method to fabricate transparent, flexible optical windows of biocompatible hydrogel material for repeated, long-term optical recordings and stroke monitoring of rodent cortex. The main advantage of the proposed method is that the optical window of any desired shape and size can be conveniently fabricated in a short span of time. The fabrication of the optical window is simple and completed in a single step. Biocompatible hydrogel poly (ethylene glycol) diacrylate (PEGDA) in the liquid form before curing conforms well to the required shape and size after cross linking. Being a light, transparent and stretchable material provide a practical solution to long- term optical imaging in the anesthetized rat.

AB - In this work, we present a single-step method to fabricate transparent, flexible optical windows of biocompatible hydrogel material for repeated, long-term optical recordings and stroke monitoring of rodent cortex. The main advantage of the proposed method is that the optical window of any desired shape and size can be conveniently fabricated in a short span of time. The fabrication of the optical window is simple and completed in a single step. Biocompatible hydrogel poly (ethylene glycol) diacrylate (PEGDA) in the liquid form before curing conforms well to the required shape and size after cross linking. Being a light, transparent and stretchable material provide a practical solution to long- term optical imaging in the anesthetized rat.

KW - Optical Window

KW - Brain Imaging

U2 - 10.1109/NANO.2018.8626270

DO - 10.1109/NANO.2018.8626270

M3 - Conference contribution

VL - 2018-July

BT - 18th International Conference on Nanotechnology, NANO 2018

CY - Cork

ER -

A Clear, Delicate, Biocompatible Optical Window for Brain Imaging

Abstract

Keywords

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Research output

Versatile microfluidic platform embedded with sidewall three-dimensional electrodes for cell manipulation

Cite this