A Clear, Delicate, Biocompatible Optical Window for Brain Imaging

Srinivasu Puttaswamy, Aishwarya Bandla, Sam Fishlock, Chengkuo Lee, James McLaughlin

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Abstract

In this work, we present a single-step method to fabricate transparent, flexible optical windows of biocompatible hydrogel material for repeated, long-term
optical recordings and stroke monitoring of rodent cortex. The main advantage of the proposed method is that the optical window of any desired shape and size can be conveniently fabricated in a short span of time. The fabrication of the optical window is simple and completed in a single step. Biocompatible hydrogel poly (ethylene glycol) diacrylate (PEGDA) in the liquid form before curing conforms well to the required shape and size after cross linking. Being a light, transparent and stretchable material provide a practical solution to long- term optical imaging in the anesthetized rat.
LanguageEnglish
Title of host publication18th International Conference on Nanotechnology, NANO 2018
Place of PublicationCork
Volume2018-July
ISBN (Electronic)9781538653364
DOIs
Publication statusPublished - 24 Jan 2019

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brain
rodents
transparence
cortexes
curing
strokes
rats
glycols
ethylene
recording
fabrication
liquids

Keywords

  • Optical Window
  • Brain Imaging

Cite this

Puttaswamy, S., Bandla, A., Fishlock, S., Lee, C., & McLaughlin, J. (2019). A Clear, Delicate, Biocompatible Optical Window for Brain Imaging. In 18th International Conference on Nanotechnology, NANO 2018 (Vol. 2018-July). [8626270] Cork. https://doi.org/10.1109/NANO.2018.8626270
Puttaswamy, Srinivasu ; Bandla, Aishwarya ; Fishlock, Sam ; Lee, Chengkuo ; McLaughlin, James. / A Clear, Delicate, Biocompatible Optical Window for Brain Imaging. 18th International Conference on Nanotechnology, NANO 2018. Vol. 2018-July Cork, 2019.
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Puttaswamy, S, Bandla, A, Fishlock, S, Lee, C & McLaughlin, J 2019, A Clear, Delicate, Biocompatible Optical Window for Brain Imaging. in 18th International Conference on Nanotechnology, NANO 2018. vol. 2018-July, 8626270, Cork. https://doi.org/10.1109/NANO.2018.8626270

A Clear, Delicate, Biocompatible Optical Window for Brain Imaging. / Puttaswamy, Srinivasu; Bandla, Aishwarya ; Fishlock, Sam; Lee, Chengkuo ; McLaughlin, James.

18th International Conference on Nanotechnology, NANO 2018. Vol. 2018-July Cork, 2019. 8626270.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

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T1 - A Clear, Delicate, Biocompatible Optical Window for Brain Imaging

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AB - In this work, we present a single-step method to fabricate transparent, flexible optical windows of biocompatible hydrogel material for repeated, long-term optical recordings and stroke monitoring of rodent cortex. The main advantage of the proposed method is that the optical window of any desired shape and size can be conveniently fabricated in a short span of time. The fabrication of the optical window is simple and completed in a single step. Biocompatible hydrogel poly (ethylene glycol) diacrylate (PEGDA) in the liquid form before curing conforms well to the required shape and size after cross linking. Being a light, transparent and stretchable material provide a practical solution to long- term optical imaging in the anesthetized rat.

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Puttaswamy S, Bandla A, Fishlock S, Lee C, McLaughlin J. A Clear, Delicate, Biocompatible Optical Window for Brain Imaging. In 18th International Conference on Nanotechnology, NANO 2018. Vol. 2018-July. Cork. 2019. 8626270 https://doi.org/10.1109/NANO.2018.8626270