A Clear, Delicate, Biocompatible Optical Window for Brain Imaging

Srinivasu Puttaswamy, Aishwarya Bandla, Sam Fishlock, Chengkuo Lee, James McLaughlin

Research output: Chapter in Book/Report/Conference proceedingConference contribution

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Abstract

In this work, we present a single-step method to fabricate transparent, flexible optical windows of biocompatible hydrogel material for repeated, long-term
optical recordings and stroke monitoring of rodent cortex. The main advantage of the proposed method is that the optical window of any desired shape and size can be conveniently fabricated in a short span of time. The fabrication of the optical window is simple and completed in a single step. Biocompatible hydrogel poly (ethylene glycol) diacrylate (PEGDA) in the liquid form before curing conforms well to the required shape and size after cross linking. Being a light, transparent and stretchable material provide a practical solution to long- term optical imaging in the anesthetized rat.
Original languageEnglish
Title of host publication18th International Conference on Nanotechnology, NANO 2018
Place of PublicationCork
Volume2018-July
ISBN (Electronic)9781538653364
DOIs
Publication statusPublished - 24 Jan 2019

Keywords

  • Optical Window
  • Brain Imaging

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  • Research Output

    Versatile microfluidic platform embedded with sidewall three-dimensional electrodes for cell manipulation

    Puttaswamy, S., Fishlock, S., Steele, D., Shi, Q., Lee, C. & McLaughlin, J., 7 Aug 2019, In : Biomedical Physics & Engineering Express. 5, 5, p. 1-37 37 p.

    Research output: Contribution to journalArticle

    Open Access
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    Cite this

    Puttaswamy, S., Bandla, A., Fishlock, S., Lee, C., & McLaughlin, J. (2019). A Clear, Delicate, Biocompatible Optical Window for Brain Imaging. In 18th International Conference on Nanotechnology, NANO 2018 (Vol. 2018-July). [8626270]. https://doi.org/10.1109/NANO.2018.8626270