• Cromore Road, Coleraine Campus

    BT52 1SA Coleraine

    United Kingdom

  • 1044 Citations
  • 20 h-Index
1985 …2020

Research output per year

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Research Output

2020
Open Access
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1 Downloads (Pure)
Open Access
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2019

An exploratory analysis investigating blood protein biomarkers to augment ECG diagnosis of ACS

McGilligan, V. E., Watterson, S., Rjoob, K., El Chemaly, M., Bond, RR., Iftikhar, A., Knoery, C., Leslie, S., McShane, A. & Bjourson, AJ., 31 Dec 2019, In : Journal of Electrocardiology. 57, p. S92-S97

Research output: Contribution to journalArticle

Open Access
File
2 Citations (Scopus)
15 Downloads (Pure)

A systematic review of suggested molecular strata, biomarkers and their tissue sources in ALS

Vijayakumar, G., Milla, V., Stafford, M. Y. C., Bjourson, AJ., Duddy, W. & Duguez, S., 14 May 2019, In : Frontiers in Neurology. 10, MAY, 400.

Research output: Contribution to journalReview article

Open Access
8 Citations (Scopus)

Can blood biomarkers augment ECG interpretation?

McGilligan, V. E., Bond, RR., Watterson, S., Bjourson, AJ., Rjoob, K., Iftikhar, A., El Chemaly, M., Peace, A., Leslie, S. & Knoery, C., 1 May 2019.

Research output: Contribution to conferenceAbstract

Comparative proteomics analyses in light-chain cardiac amyloidosis and acute coronary syndrome

Harrigan, R., El Chemaly, M., Shukla, P., Egan, P., Drain, S., Elder, P., McGilligan, V. E., Peace, A., Bjourson, AJ. & Alexander, H. D., 11 Sep 2019.

Research output: Contribution to conferencePoster

Open Access
File
12 Downloads (Pure)

InflaMab: A novel NLRP3 Inflammasome inhibitor tested in a mouse model of glaucoma

McGilligan, V. E., El Chemaly, M., Gregory-Ksander, M., Bjourson, AJ. & Peace, A., 31 Oct 2019.

Research output: Contribution to conferenceAbstract

Open Access
File
6 Citations (Scopus)
4 Downloads (Pure)

Readiness to change and barriers to treatment seeking in college students with a mental disorder

Ennis, E., McLafferty, M., Murray, EK., Lapsley, C., Bjourson, AJ., Armour, C., Bunting, B., Murphy, SD. & O'Neill, S., 1 Jun 2019, In : Journal of Affective Disorders. 252, p. 428-434 7 p.

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
7 Downloads (Pure)

Stratification of Type-2 Diabetes comorbidities using genotypic array and Machine Learning

Villikudathil, A., Mc Guigan, D., English, A., Kelly, C., McClean, P., Bjourson, AJ. & Shukla, P., 22 Jan 2019, 21st Meeting of the Irish Society of Human Genetics. Ulster Medical Journal, Vol. 88(1). p. 70

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Open Access

Stratifying patients with inflammatory diseases based on treatment response

Prasad, B., Gibson, D., McGeough, C., Eakin, A., Ahmed, T., Small, D., Gardiner, P., Pendleton, A., Wright, G., Bjourson, AJ. & Shukla, P., 2019.

Research output: Contribution to conferencePoster

The NLRP3 Inflammasome as a promising target for Coronary Artery Disease: Current and Pipeline NLRP3 Inhibitors

McGilligan, V. E., Mcallister, R., Chemaly, M., Bjourson, AJ. & Peace, A., 13 Nov 2019, In : Online Journal of Cardiovascular Research. 2, 3, p. 1 7 p.

Research output: Contribution to journalLiterature review

File
99 Downloads (Pure)
2018

A hybrid computational approach for efficient Alzheimer’s disease classification based on heterogeneous data

Ding, X., Bucholc, M., Wang, H. . HY., Glass, D. H., Wang, H., Clarke, D., Bjourson, AJ., Dowey, L., O'Kane, M., Prasad, G., Maguire, L. & Wong-Lin, K., 27 Jun 2018, In : Scientific Reports. p. 1-10 10 p., 9774 (2018).

Research output: Contribution to journalArticle

Open Access
File
6 Citations (Scopus)
25 Downloads (Pure)

Development of a computer-based clinical decision support tool for identifying individuals with different levels of cognitive impairment

Bucholc, M., Ding, X., Wang, H. . HY., Glass, D. H., Wang, H., Prasad, G., Maguire, L., Bjourson, AJ., McClean, P., Todd, S., Finn, D. & Wong-Lin, K., 20 Mar 2018, Unknown host publication.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Development of a machine learning classifier for stratification of type-2 diabetes based on associated comorbidities

Villikudathil, A., Mc Guigan, D., English, A., Kelly, C., McClean, P., Bjourson, AJ. & Shukla, P., 12 Sep 2018, Development of a machine learning classifier for stratification of type-2 diabetes based on associated comorbidities.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Machine learning based model development for the prediction of miRNAs involved in EMT using NGS data

Doherty, G., Bjourson, AJ. & Shukla, P., 12 Sep 2018, Machine learning based model development for the prediction of miRNAs involved in EMT using NGS data.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Proteomics analyses in light-chain cardiac amyloidosis

Harrigan, R., Shukla, P., Egan, P., Elder, P., Drain, S., El Chemaly, M., Bjourson, AJ. & Alexander, H. D., 12 Sep 2018, Proteomics analyses in light-chain cardiac amyloidosis.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Open Access
File
1 Citation (Scopus)
27 Downloads (Pure)
Open Access
File
14 Citations (Scopus)
207 Downloads (Pure)
2017

Association of baseline cytokine levels with anti-tumour necrosis factor treatment response in rheumatoid arthritis

Gibson, D. S., McGeough, C. M., Slevin, M. M., Wright, G., Gardiner, P., Murray, H. A., Latten, M. J., Crockard, M. A., Lamont, J. V. & Bjourson, T., 1 May 2017, In : JOURNAL OF IMMUNOLOGY. 198, 1 Supp, p. 201.7-201.7

Research output: Contribution to journalArticle

Open Access
File
7 Downloads (Pure)
Open Access
2 Citations (Scopus)

Data analytics and computerised application for predicting Alzheimer’s disease severity and related outlier test scores

Bucholc, M., Ding, X., Wang, H. . HY., Glass, D. H., Wang, H., Bjourson, AJ., Dowey, L., O'Kane, M., Maguire, L., Prasad, G. & Wong-Lin, K., 20 Sep 2017, Unknown host publication.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

KRAS mutant colorectal cancer gene signatures identified angiotensin II receptor blockers as potential therapies

Wen, Q., Dunne, P. D., O’Reilly, P. G., Li, G., Bjourson, T., McArt, D. G., Hamilton, P. W. & Zhang*, S-D., 10 Jan 2017, In : Oncotarget. 8, 2, p. 3206-3225 19 p.

Research output: Contribution to journalArticle

Open Access
File
5 Citations (Scopus)
9 Downloads (Pure)
Open Access
File
24 Citations (Scopus)
11 Downloads (Pure)

Metabolic and neuroprotective effects of dapagliflozin and liraglutide in diabetic mice

Millar, P., Pathak, N., Parthsarathy, V., Bjourson, AJ., O'Kane, M., Pathak, V., Moffett, C., Flatt, P. & Gault, V. A., 23 Jun 2017, (Accepted/In press) In : Journal of Endrocrinology. 234, 3, p. 255-267

Research output: Contribution to journalArticle

Open Access
22 Citations (Scopus)

Role of tumour necrosis factor alphaconverting enzyme (TACE/ADAM17) andassociated proteins in coronary arterydisease and cardiac events

Chemaly, M., McGilligan, VE., Gibson, M., Clauss, M., Watterson, S., Alexander, HD., Bjourson, AJ. & Peace, A., 31 Oct 2017, In : Archives of Cardiovascular Diseases. 110, p. 700-711

Research output: Contribution to journalArticle

4 Citations (Scopus)

Role of tumour necrosis factor alpha converting enzyme (TACE/ADAM17) and associated proteins in coronary artery disease and cardiac events

El Chemaly, M., McGilligan, V. E., Gibson, M., Clauss, M., Watterson, S., Alexander, H. D., Bjourson, AJ. & Peace, A., 31 Oct 2017, In : Archives of Cardiovascular Diseases. 110, 12, p. 700-711 12 p., ACVD-1047.

Research output: Contribution to journalArticle

Open Access
File
8 Downloads (Pure)

The association of monocytes and Tregs with disease activity in rheumatoid arthritis

Eakin, AJ., Ahmed, T., McGeough, C. M., Alexander, H., Wright, G. D., Gardiner, P. V., Bjourson, AJ. & Gibson, DS., 1 May 2017, In : JOURNAL OF IMMUNOLOGY. 198, 1 Supp, p. 55.12-55.12

Research output: Contribution to journalArticle

2016

A Metagenomic Hybrid Classifier for Paediatric Inflammatory Bowel Disease

Wingfield, B., Coleman, SA., McGinnity, T. M. & Bjourson, AJ., 3 Nov 2016, Unknown Host Publication. IEEE, p. 1083-1089 7 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Open Access
File
3 Citations (Scopus)
14 Downloads (Pure)

Beneficial metabolic actions of a stable GIP agonist following pre-treatment with a SGLT2 inhibitor in high fat fed diabetic mice

Millar, PJ., Pathak, V., Moffett, C., Pathak, NM., Bjourson, AJ., OKane, MJ., Flatt, P. & Gault, V., 15 Jan 2016, In : Molecular and Cellular Endocrinology. 420, p. 37-45 9 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Design of a Multiplex Serum Proteome Assay to Monitor Biologic Drug Response in Rheumatoid Arthritis Patients

Callan, N., Butt, A., Pennington, SR., McGeough, C., Gardiner, P., Wright, G., Bjourson, AJ. & Gibson, DS., 28 Sep 2016, In : Arthritis and Rheumatology. 68, Suppl

Research output: Contribution to journalArticle

Open Access
File
1 Downloads (Pure)

Siglec 1 and 2 as potential biomarkers in autoimmune disease

Eakin, A., Bustard, M., McGeough, C., Ahmed, T., Bjourson, AJ. & Gibson, D., 1 Jun 2016, In : PROTEOMICS - Clinical Applications. TBC

Research output: Contribution to journalArticle

Open Access
3 Citations (Scopus)

Towards Stratified Medicine in Plasma Cell Myeloma

Egan, P., Drain, S., Conway, C., Bjourson, T. & Alexander, H. D., 21 Oct 2016, In : International Journal of Molecular Sciences. 17, 10, p. 1760

Research output: Contribution to journalArticle

Open Access
File
4 Citations (Scopus)
21 Downloads (Pure)
2015

Current and future trends in biomarker discovery and development of companion diagnostics for arthritis

Gibson, D., Bustard, M., McGeough, C., Murray, H. A., Crockard, M. A., Mc Dowell, A., Blayney, J., Gardiner, P. & Bjourson, AJ., 2015, In : Expert Review of Molecular Diagnostics. 15, 2

Research output: Contribution to journalArticle

8 Citations (Scopus)
2013

Prevalence of KIR B haplotype in Irish rheumatoid arthritis patients

McGeough, C., Gibson, D., Slevin, M., Wright, G., Gardiner, P., Fitzgerald, O. & Bjourson, AJ., 2013, Annals of Rheumatic Disease. BMJ Publishing Group, Vol. 72. p. A786 1 p.

Research output: Chapter in Book/Report/Conference proceedingConference contribution

Open Access

Purification, characterization and molecular cloning of chymotrypsin inhibitor peptides from the venom of Burmese Daboia russelli siamensis

Guo, C., McClean, S., Shaw, C., Rao, P., Ye, M. & Bjourson, AJ., May 2013, In : Peptides. 43, p. 126- 132

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)

Trypsin and chymotrypsin inhibitor peptides from the venom of Chinese Daboia russellii siamensis

Guo, C., McClean, S., Shaw, C., Rao, P., Ye, M. & Bjourson, AJ., 2013, In : Toxicon. 63, p. 154-164

Research output: Contribution to journalArticle

Open Access
16 Citations (Scopus)
2012
Open Access
File
39 Downloads (Pure)

Killer immunoglobulin-like receptor and human leukocyte antigen-C genotypes in rheumatoid arthritis primary responders and non-responders to anti-TNF-α therapy

McGeough, C., Berrar, D., Wright, G., Mathews, C., Gilmore, P., Cunningham, R. T. & Bjourson, AJ., 2 Jun 2012, In : Rheumatology International. 32, 6, p. 1647-1653

Research output: Contribution to journalArticle

Open Access
17 Citations (Scopus)

Neither P-gp SNP variants, P-gp expression nor functional P-gp activity predicts MDR in a preliminary study of plasma cell myeloma

Drain, S., Catherwood, M. A., Bjourson, AJ., Drake, M. B., Kettle, P. J. & Alexander, H. D., 2012, In : Cytometry Part B: Clinical Cytometry. TBC, p. n/a

Research output: Contribution to journalArticle

Open Access
5 Citations (Scopus)
2011

Killer immunoglobulin-like receptor and human leukocyte antigen-C genotypes in rheumatoid arthritis primary responders and non-responders to anti-TNF-α therapy

McGeough, C., Berrar, D., Wright, G., Mathews, C., Gilmore, P., Cunningham, R. T. & Bjourson, AJ., 2011, In : Rheumatology International. 32, 6, p. 1647

Research output: Contribution to journalArticle

Open Access
File
5 Downloads (Pure)

Multidrug resistance gene expression and ABCB1 SNPs in plasma cell myeloma

Drain, S., Flannely, L., Drake, M. B., Kettle, P., Orr, N., Bjourson, AJ., Catherwood, M. A. & Alexander, H. D., 2011, In : Leukemia Research. 35, 11, p. 1457-1463

Research output: Contribution to journalArticle

Open Access
15 Citations (Scopus)
2010

METHOD OF STRATIFYING BREAST CANCER PATIENTS BASED ON GENE EXPRESSION

Bjourson, AJ., Berrar, D. & McErlean, S., 10 Jun 2010, Patent No. PCT/EP2009/008563, Priority No. WO/2010/063454

Research output: Patent

2009

USE OF KIR GENES FOR PREDICTING RESPONSE TO THERAPY

Bjourson, AJ., Berrar, D. & McGeough, C., 18 Jun 2009, Patent No. PCT/EP2008/010547., Priority No. WO/2009/074326.

Research output: Patent

2007
Open Access
36 Citations (Scopus)
31 Citations (Scopus)

Bradykinin-related peptides, including a novel structural variant, (Val(1))-bradykinin, from the skin secretion of Guenther's frog, Hylarana guentheri and their molecular precursors

Zhou, J. W., Bjourson, AJ., Coulter, D., Chen, T. B., Shaw, C., O'Rourke, M., Hirst, D. G., Zhang, Y. N., Rao, P. F. & McClean, S., Apr 2007, In : Peptides. 28, 4, p. 781-789

Research output: Contribution to journalArticle

6 Citations (Scopus)