Research output per year
Research output per year
Personal profile
Biography
Professor Tony Bjourson is Director of the Northern Ireland Centre for Stratified Medicine which he established at Altnagelvin (C-TRIC) in 2013 with an award of £11.5M. He is PI on a multicentre grant that established an €8.6M (EU SEUPB) Centre for Personalised Medicine Patient Safety and Clinical Decision Making. He was a Co-applicant on a jointly funded MRC award to Belfast City Hospital to establish a Northern Ireland Centre for Genomic Medicine. He is also Co-PI on a £0.7M Personalised Medicine Mental Health Project recently awarded. He obtained his MSc in Molecular Biosciences from the University of Ulster and PhD from Queen’s University Belfast. He has published extensively and has >30 years of research experience. Prior to joining Ulster in 2001, he established and managed genomic programmes for the DARDNI and Queens University Belfast and participated in the first international eukaryotic genome project (EU Yeast Genome sequencing program 1994-1996). After joining Ulster he led the Pharmaceutical Biotechnology Research Group and subsequently established and led the Biomedical Genomics Research Group. He was founder and serves as a Director on the board of the Clinical Translation Research & Innovation Centre (C-TRIC) based in L/Derry aimed at translating biomedical research outputs from laboratory bench to patient bedside. He also served on the Board of Directors of the Ulster venture company Innovation Ulster Ltd. He is a Steering Committee member of the Northern Ireland Biobank, a Council Member of the Irish Society for Human Genetics. He has personally secured in excess of £28M in research grants and has supervised >25 PhD students to successful completion. His own current research is focused on stratified and personalised medicine in the area of multi-morbid diseases with an inflammatory aetiology. He is currently leading the further expansion of an expanded £24M personalised medicine Health Research Institute funded by the UK Government City Deals (awarded to Derry City and Strabane District Council).
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Research Funding (Focused on Stratified Personalised medicine):
Professor Bjourson has secured > £30 M to support Research and he is currently PI on grants >£20M solely relating to Stratified /Personalised Medicine/Clinical Decision Making.
2017-2018 The Genomic Basis of Multiple Sclerosis in Ireland, Genomics Medicine Ireland (GMI) £100,000 (Bjourson, PI) 2017-2018 The Genomic Basis of Inflammatory Bowel Disease in Ireland, Genomics Medicine Ireland (GMI) £100,000 (Bjourson, PI) 2017-2022 Centre for Clinical Decision Making and Patient Safety, EU (ERDF/SEUPB) €8.6M. (Bjourson PI with Co-PI multidisciplinary team. 2015-2018 Northern Ireland Genomic Medicine Centre (Genome England 100K Genome Project) Bjourson Co Applicant with Belfast Health & Social Care Trust and QUB) £3.3M (£0.75M MRC; 2.55 M Public Health Agency) 2014-2018, Technology Strategy Board, £249,580, Extraction and Modelling of Alzheimer's Disease Data for Patient Stratification; K Wong-Lin, AJ Bjourson, DH Glass, HY Wang, G Prasad, H Wang, L Maguire 2014-2016 Invest NI - Proof of Concept: £105,227, Development of three novel incretin-based peptide agonists for disease therapy Co-PI. 2013-2018. Northern Ireland Centre for Stratified Medicine – £11.5M (InvestNI, HSCR&D) Bjourson Sole PI. 2013-2018. NI Functional Brain Mapping Facility, £2.6M TM McGinnity, AJ, Bjourson, & P Devine 2011-2013, Stratified medicines programme: Inflammatory biomarkers for more effective drugs, UK Technology Strategy Board (TSB) -Medical Research Council (MRC); Multiplex SNP array for the stratification of therapy response in rheumatoid arthritis patients; Total Project Cost: £809,574 (£324,561 awarded to Bjourson, Prof AJ as PI) 2010-2013. Breast Cancer Personalised Medicine Biomarkers, Randox Research Fellowship in Personalised Medicine: £284,000. Randox Laboratories Ltd. Bjourson, Prof AJ (Sole PI) 2011-2016 Norbrook Laboratories Chair In Pharmaceutical Sciences, (University of Ulster team: Barnett, R.; McClenaghan, N; Bjourson, A.J.) £1M 2010-2013 Funding for Technician within C-TRIC, Western Health & Social Care Trust (WHSCT) £85,000 Strategic Initiatives Award for Biomedical Science. 2009-2011 – Department of Education & Learning Research Infrastructure Fund (DEL RIF); £2,7M; Bjourson, Prof AJ (Sole PI) 2008 Academia-Business-Clinical Research Facility (ABC-RF) now established as C-TRIC –Altnagelvin Hospital Site (Bjourson, Prof AJ (Co- PI), partnership between the Western Health and Social Care Trust, University of Ulster and Derry City Council) - £1.764 M (£1.3 M INI Intereg IIIa Programme; £464 K ILEX Integrated Development Fund-IDF). Personalised Medicine in Breast Cancer: Predicting metastases-free survival in lymph-node negative breast cancer patients InvestNI Proof of Concept Grant:, £79,000,Bjourson, Prof AJ (Sole PI) 2004-2009. NUGO - Impact of Food on Health - Linking Genomics, Nutrition and Health Research. C.E.C. – EU Framework 6 Food Quality & Safety NOE £15,536 (Bjourson, Prof AJ (Co PI with Prof. S. Train et al) 2004-2007, BRCA1 and BRCA2 Status Breast/Ovarian Cancer Families in Northern Ireland (Bjourson, Prof AJ (PI); Co-Applicants Barnett, Prof YA Garsin, Mr I Morrison, Prof P ). HPSS R&D Office (Cancer Recognised Research Group). £145,000. 2002-2007 Late cell cycle checkpoints in cancer. R&D Office HPSS RRG, £613,013., Downes, Prof CS , Bjourson, Prof AJ McGlynn, Dr HG |
Web sites:
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Master, Contemporary Biological Sciences
2000 → 2002
Award Date: 1 Sept 2002
PhD, PhD Molecular Signalling, Queens University Belfast, Northern Ireland
1992 → 1996
Award Date: 1 Jun 1996
External positions
Director of C-TRIC (Clinical Translational Research & Innovation Centre)
Jun 2008 → …
Keywords
- RZ Other systems of medicine
- Personalised Medicine
- Stratified Medicine
- Precision Medicine
- Q Science (General)
- Genomics
- Personalised Medicine
- Precision Medicine
- Stratified Medicine
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Collaborations and top research areas from the last five years
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Methylome profiling of young adults with depression supports a link with immune response and psoriasis
Lapsley, C., Irwin, R. E., Mc Lafferty, M., Thursby, S.-J., O'Neill, S., Bjourson, A., Walsh, C. & Murray, E., 2 Jul 2020, In: Clinical Epigenetics. 12, 1, 16 p., 85.Research output: Contribution to journal › Article › peer-review
Open AccessFile9 Citations (Scopus)125 Downloads (Pure) -
An exploratory analysis investigating blood protein biomarkers to augment ECG diagnosis of ACS
McGilligan, V. E., Watterson, S., Rjoob, K., El Chemaly, M., Bond, R., Iftikhar, A., Knoery, C., Leslie, S., McShane, A. & Bjourson, A., 31 Dec 2019, In: Journal of Electrocardiology. 57, p. S92-S97Research output: Contribution to journal › Article › peer-review
Open AccessFile4 Citations (Scopus)171 Downloads (Pure) -
The NLRP3 Inflammasome as a promising target for Coronary Artery Disease: Current and Pipeline NLRP3 Inhibitors
McGilligan, V. E., Mcallister, R., Chemaly, M., Bjourson, A. & Peace, A., 13 Nov 2019, In: Online Journal of Cardiovascular Research. 2, 3, p. 1 7 p.Research output: Contribution to journal › Literature review › peer-review
File278 Downloads (Pure) -
A systematic review of suggested molecular strata, biomarkers and their tissue sources in ALS
Vijayakumar, G., Milla, V., Stafford, C., Bjourson, A., Duddy, W. & Duguez, S., 14 May 2019, In: Frontiers in Neurology. 10, MAY, 17 p., 400.Research output: Contribution to journal › Review article › peer-review
Open AccessFile59 Citations (Scopus)81 Downloads (Pure) -
Anti-tumour necrosis factor-alpha response associated with combined CD226 and HLA-DRB1*0404 haplotype in rheumatoid arthritis.
Gibson, D. S., McGeough, C. M., Watterson, S., Blayney, J., Wright, G. D., Pendleton, A., Gardiner, P., Small, D., Eakin, A. J., Ahmed, T., Murray, H. A., Latten, M. J., Crockard, M. A., Lamont, J. V., Zhang, S. D. & Bjourson, A. J., 9 Apr 2021, In: Clinical and Experimental Rheumatology. 39, 2, p. 385-392 8 p.Research output: Contribution to journal › Article › peer-review
Open AccessFile5 Citations (Scopus)119 Downloads (Pure)
Prizes
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Ulster University Research Excellence Award - Business Category (Under 50 employees)
Bucholc, M. (Recipient), Ding, X. (Recipient), Wong-Lin, K. (Recipient), Maguire, L. (Recipient), Devine, P. (Recipient), Wang, H. /. H. (Recipient), Glass, D. H. (Recipient), Wang, H. (Recipient), Prasad, G. (Recipient), Bjourson, A. (Recipient), Dowey, L. (Recipient) & Price, R. (Recipient), 9 May 2019
Prize