• Cromore Road, Coleraine Campus

    BT52 1SA Coleraine

    United Kingdom

  • 1025 Citations
  • 20 h-Index
1985 …2020

Research output per year

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Personal profile

Biography

Professor Tony Bjourson  is Director of the Northern Ireland Centre for Stratified Medicine which he established at Altnagelvin (C-TRIC) in 2013 with an award of £11.5M. He is PI on a multicentre grant that established an €8.6M (EU SEUPB) Centre for Personalised Medicine Patient Safety and Clinical Decision Making.  He was a Co-applicant on a jointly funded MRC award to Belfast City Hospital to establish a Northern Ireland Centre for Genomic Medicine.  He is also Co-PI on a £0.7M Personalised Medicine Mental Health Project recently awarded.  He obtained his MSc in Molecular Biosciences from the University of Ulster and PhD from Queen’s University Belfast.  He has published extensively and has >30 years of research experience.  Prior to joining Ulster in 2001, he established and managed genomic programmes for the DARDNI and Queens University Belfast and participated in the first international eukaryotic genome project (EU Yeast Genome sequencing program 1994-1996).  After joining Ulster he led the Pharmaceutical Biotechnology Research Group and subsequently established and led the Biomedical Genomics Research Group.   He was founder and serves as a Director on the board of the Clinical Translation Research & Innovation Centre (C-TRIC) based in L/Derry aimed at translating biomedical research outputs from laboratory bench to patient bedside.  He also served on the Board of Directors of the Ulster venture company Innovation Ulster Ltd.  He is a Steering Committee member of the Northern Ireland Biobank, a Council Member of the Irish Society for Human Genetics. He has personally secured in excess of £28M in research grants and has supervised >25 PhD students to successful completion.  His own current research is focused on stratified and personalised medicine in the area of multi-morbid diseases with an inflammatory aetiology.  He is currently leading the further expansion of an expanded £24M personalised medicine Health Research Institute funded by the UK Government City Deals (awarded to Derry City and Strabane District Council).

 

Research Funding (Focused on Stratified Personalised medicine):

 

Professor Bjourson has secured > £30 M to support Research and he is currently PI on grants >£20M solely relating to Stratified /Personalised Medicine/Clinical Decision Making. 


2018-2022 2018-2022 Improving mental health among at-risk young people in a challenging border region CHITIN INTERREG (Special EU Programms Body-SEUPB) €0.7M (Elaine Murray PI, Bjourson C0-PI)

2017-2018 The Genomic Basis of Multiple Sclerosis in Ireland, Genomics Medicine Ireland (GMI) £100,000 (Bjourson, PI)

2017-2018 The Genomic Basis of Inflammatory Bowel Disease in Ireland, Genomics Medicine Ireland (GMI) £100,000 (Bjourson, PI)

2017-2022 Centre for Clinical Decision Making and Patient Safety, EU (ERDF/SEUPB) €8.6M. (Bjourson PI with Co-PI multidisciplinary team.

2015-2018 Northern Ireland Genomic Medicine Centre (Genome England 100K Genome Project) Bjourson Co Applicant with Belfast Health & Social Care Trust and QUB) £3.3M (£0.75M MRC; 2.55 M Public Health Agency)

2014-2018, Technology Strategy Board, £249,580, Extraction and Modelling of Alzheimer's Disease Data for Patient Stratification; K Wong-Lin, AJ Bjourson, DH Glass, HY Wang,  G Prasad, H Wang, L Maguire

2014-2016 Invest NI - Proof of Concept:  £105,227, Development of three novel incretin-based peptide agonists for disease therapy Co-PI.

2013-2018. Northern Ireland Centre for Stratified Medicine – £11.5M (InvestNI, HSCR&D) Bjourson Sole PI. 

2013-2018. NI Functional Brain Mapping Facility,  £2.6M TM McGinnity, AJ, Bjourson, & P Devine

2011-2013, Stratified medicines programme: Inflammatory biomarkers for more effective drugs,  UK Technology Strategy Board (TSB) -Medical Research Council (MRC); Multiplex SNP array for the stratification of therapy response in rheumatoid arthritis patients; Total Project Cost: £809,574 (£324,561 awarded to  Bjourson, Prof AJ as PI)

2010-2013. Breast Cancer Personalised Medicine Biomarkers, Randox Research Fellowship in Personalised Medicine:  £284,000.  Randox Laboratories Ltd. Bjourson, Prof AJ (Sole PI)

2011-2016 Norbrook Laboratories Chair In Pharmaceutical Sciences, (University of Ulster team: Barnett, R.; McClenaghan, N; Bjourson, A.J.) £1M 

2010-2013 Funding for Technician within C-TRIC, Western Health & Social Care Trust (WHSCT) £85,000

Strategic Initiatives Award for Biomedical Science. 2009-2011 – Department of Education & Learning Research Infrastructure Fund (DEL RIF); £2,7M;  Bjourson, Prof AJ (Sole PI)

2008 Academia-Business-Clinical Research Facility (ABC-RF) now established as C-TRIC –Altnagelvin Hospital Site (Bjourson, Prof AJ (Co- PI), partnership between the Western Health and Social Care Trust, University of Ulster and Derry City Council) -  £1.764 M (£1.3 M INI Intereg IIIa Programme; £464 K ILEX Integrated Development Fund-IDF).

Personalised Medicine in Breast Cancer: Predicting metastases-free survival in lymph-node negative breast cancer patients InvestNI Proof of Concept Grant:, £79,000,Bjourson, Prof AJ (Sole PI)

2004-2009. NUGO - Impact of Food on Health - Linking Genomics, Nutrition and Health Research.  C.E.C. – EU Framework 6 Food Quality & Safety NOE   £15,536  (Bjourson, Prof AJ (Co PI with Prof. S. Train et al)

2004-2007,  BRCA1 and BRCA2 Status Breast/Ovarian Cancer Families in Northern Ireland (Bjourson, Prof AJ (PI); Co-Applicants Barnett, Prof YA Garsin, Mr I Morrison, Prof P ).  HPSS R&D Office (Cancer Recognised Research Group).  £145,000.

2002-2007 Late cell cycle checkpoints in cancer. R&D Office HPSS RRG, £613,013., Downes, Prof CS , Bjourson, Prof AJ McGlynn, Dr HG

Web sites:

https://www.ulster.ac.uk/research/institutes/biomedical-sciences/research/northern-ireland-centre-for-stratified-medicine

https://www.ulster.ac.uk/research/institutes/biomedical-sciences/research/centre-for-personalised-medicine

Education/Academic qualification

Master

20002002

PhD, Queens University Belfast, Northern Ireland

19921996

External positions

Director of C-TRIC (Clinical Translational Research & Innovation Centre)

Jun 2008 → …

Keywords

  • RZ Other systems of medicine
  • Personalised Medicine
  • Stratified Medicine
  • Precision Medicine
  • Q Science (General)
  • Genomics
  • Personalised Medicine
  • Precision Medicine
  • Stratified Medicine

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Research Output

Open Access
File
  • Open Access
    File
  • An exploratory analysis investigating blood protein biomarkers to augment ECG diagnosis of ACS

    McGilligan, V. E., Watterson, S., Rjoob, K., El Chemaly, M., Bond, RR., Iftikhar, A., Knoery, C., Leslie, S., McShane, A. & Bjourson, AJ., 31 Dec 2019, In : Journal of Electrocardiology. 57, p. S92-S97

    Research output: Contribution to journalArticle

  • Open Access
    File
  • 1 Citation (Scopus)
    12 Downloads (Pure)

    A systematic review of suggested molecular strata, biomarkers and their tissue sources in ALS

    Vijayakumar, G., Milla, V., Stafford, M. Y. C., Bjourson, AJ., Duddy, W. & Duguez, S., 14 May 2019, In : Frontiers in Neurology. 10, MAY, 400.

    Research output: Contribution to journalReview article

    Open Access
  • 5 Citations (Scopus)

    Prizes

    Ulster University Research Excellence Award - Business Category (Under 50 employees)

    Magda Bucholc (Recipient), Xuemei Ding (Recipient), Kongfatt Wong-Lin (Recipient), Liam Maguire (Recipient), Peter Devine (Recipient), Haiying / HY Wang (Recipient), David H. Glass (Recipient), H. Wang (Recipient), Girijesh Prasad (Recipient), AJ Bjourson (Recipient), L Dowey (Recipient) & RK Price (Recipient), 9 May 2019

    Prize

    Thesis

    Discovery of circulating DMARD response biomarkers in rheumatoid arthritis

    Author: Eakin, A., Apr 2018

    Supervisor: Gibson, D. (Supervisor) & Bjourson, A. (Supervisor)

    Student thesis: Doctoral Thesis

    File

    Identifying drivers of glycaemic control in response to sulphonylurea treatment

    Author: McGuigan, D., May 2018

    Supervisor: Kelly, C. (Supervisor), Bjourson, A. (Supervisor) & Mc Clean, P. (Supervisor)

    Student thesis: Doctoral Thesis

    File

    Investigating known and novel biomarkers for risk stratification in cardiovascular disease

    Author: Chemaly, M., May 2018

    Supervisor: Mc Gilligan, V. E. (Supervisor), Bjourson, A. (Supervisor) & Peace, A. (External person) (Supervisor)

    Student thesis: Doctoral Thesis

    File

    Secretion of neurotoxic vesicles by muscle cells of ALS patients

    Author: Le Gall, L., Sep 2019

    Supervisor: Duguez, S. (Supervisor) & Bjourson, A. (Supervisor)

    Student thesis: Doctoral Thesis

    Stratified medicine approaches to identify candidate markers associated with mental health disorders

    Author: Lapsley, C., Jun 2018

    Supervisor: Bjourson, A. (Supervisor) & Murray, E. (Supervisor)

    Student thesis: Doctoral Thesis